#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

The present view of relationship between hormone replacement therapy and eye diseases


Authors: Tomáš Fait
Authors place of work: Gynekologicko-porodnická klinika 1. LF UK a VFN Praha
Published in the journal: Prakt Gyn 2005; 9(5): 20-23

Summary

The influence of hormone replacement therapy on age-related eye diseases was investigated in several observation studies. Protective primary preventive role for age-related macular degeneration was shown only in Eye Disease Case-Control Study. Blue Mountain Eye Study and Beaver Dam Study did not find significant associations. Protective role of estrogen is on border of significance for cataracta and intraocular pressure. It is in a common knowledge that sexagens increse the risk of tromboembolism. Also ocular vessels are under this danger.

The different effects of pure estrogens, combination of estrogens and gestagens and tibolone are also influenced by the dose, the way of application and the timing of therapy. The prevention of age related eye diseases surely are not indication for hormone therapy along recent findings. On the other side there is no new containdication in this medical branch.

Key words:
hormone replacement therapy, age-related eye diseases


Zdroje

1. Battaglia C, Mancini F, Regnani G et al. Hormone therapy nad ophtalmic artery blood flow changes in women with primary open-angle glaucoma. Menopause 2004; 11(1): 69-77.

2. Benitez del Catillo JM, del Rio T, Garcia-Sanchez J. Effects of estrogen use on lens transmittance in postmenopausal women. Ophtalmology 1997; 104: 970-973.

3. Bressler NM, Bressler SB. Preventive ophthalmology: age-related macular degeneration. Ophthalmology 1995; 102: 1206-1211.

4. Cumming RG, Mitchell P. HRT, reproductive factors and cataract: the Blue Mountain Eye Study. Am J Epidemiol 1997, 145, p. 242-9.

5. Defay R, Pinchinat S, Lumbroso S et al. Sex steroids and age-related macular degeneration older french women: the POLA study. Ann Epidemiol 2004; 14(3): 202-8.

6. Defay R, Pinchinat R, Lumbroso S et al. Relationship between hormonal status and cataract in french postmenopausal women: POLA study group. Ann Epidemiol 2003; 13: 638-644.

7. Eye Disease Case-Control Study Group: Risk factors for neovascular AMD. Arch Ophthalmol 1992; 110: 1701-1708.

8. Fait T, Málková J, Živný J. Vliv hormonální substituční terapie na kardiovaskulární systém. Čes Gynek 2002; 67(5): 285-293.

9. Fait T, Vokrouhlická J, Vrablík M, Jeníček J. Současné postavení hormonální substituční terapie. Čas Lék Čes 2004; 143(7): 447-452.

10. Fernandez LHS, Scassellati-Sforzolini B, Spaide M. Estrogen and visual hallucinations in a patient with Charles Bonnet syndrome. Am J Ophthalmol 2000; 129: 407.

11. Friedman S, Golan A, Shoenfeld A et al. Acute ophtalmologic complication during the use of oral contraceptives. Contraception 1974; 10(6): 685-692.

12. Goldberg J, Flowerdew G, Smith E et al. Factors associated with age-related macular degeneration: an analysis of data from the first national Health and Nutrition Examination Survey. Am J Epidemiol 1988; 128: 700-710.

13. Guaschino S, Grimaldi E, Sartore A et al. Visual function in menopause: the role of HRT. Menopause 2003; 10(1): 53-57.

14. Hales AM, Chamberlain JG, Murphy CR et al. Estrogen protects against cataract induced by TGF-beta. J Exp Med 1997; 185: 273-280.

15. Harding JJ. Estrogens and cataract (letter). Arch Ophtalmol 1994; 112: 1511.

16. Harris-Yitzak M, Harris A, Ben-Refael Z et al. ERT: Effects on retrobulbar hemodynamics. Am J Ophthalmol 2000; 129: 623-628.

17. Kahn HA, Leibowitz HM, Gynley JP et al. The Framingham Eye Study, II: Association of ophtalmic pathology with single variables previously measured in the Framingham Heart Study. Am J Epidemiol 1977; 106: 33-41.

18. Kirwan JF, Tsaloumas MD, Vinall H et al. Sex hormone preparations and retinal vein occlusion. Eye 1997; 1(Pt1): 53-56.

19. Klaver CCW, Wolfs RCW, Vingerling JR et al. Age-specific prevalence and causes of blindness and visual impairment in an older population: the Rotterdam Study. Arch Ophthalmol 1998; 116: 653-658.

20. Klein BEK, Klein R, Lee KE. Reproductive exposures, incident age-related cataracts and age-related maculopathy in women: The Beaver Dam Eye Study. Am J Ophthalmol 2000; 130: 322-326.

21. Knave B, Tengroth B, Voss M. Age and sex distribution of some retinal macular diseases. Acta Ophtalmol 1984; (Suppl 161): 95-103.

22. Kuscu NK, Toprak AB, Vatansever S et al. Tear function changes of postmenopausal women in response to hormone replacement therapy. Maturitas 2003; 44: 63-68.

23. Leske MC, Wu S-Y, Connell AMS et al. Lens opacities, demographic factors and nutritional supplements in the Barbados Eye Study. Int J Epidemiol 1997; 26: 1314-1322.

24. Liu IZ, White L, LaCroix AZ. The association of AMD and lens opacities in the aged. Am J Public Health 1989; 79: 765-769.

25. Rekhi GS, Dheer S. Oral contraceptive – induced central retinal artery occlusion. J Assoc Physicians India 2002; 50: 1084-1085.

26. Sator MO, Akramian J, Joura EA et al. Reduction of intraocular pressure in a galucoma patient undergoing hormone replacement therapy. Maturitas 1998; 29: 93-95.

27. Sator MO, Joura EA, Golaszewski T et al. Treatment of menopausal keratoconjunctivitis sicca with topical oestradiol. Br Jobstet Gynaecol 1998; 105: 100-102.

28. Seddom JM, Ajani UA, Mitchell BM. Familial aggregation of age-related maculopathy. Am J Ophthalmol 1997; 123: 199-206.

29. Seddom JM, Willett WC, Speizer FE et al. A prospective study of cigarette smoking and age related macular degeneration in women. JAMA 1996; 276: 1141-1146.

30. Schaumberg DA, Burington JE, Sullivan DA et al. HRT nad Dry Eye Syndrome. JAMA 2001; 286(17): 2114-2119.

31. Smith W, Mitchell P, Wang JJ. Gender, oestrogen, hormone replacement and AMD: results from the Blue Mountains Eys Study. Austr N Z J Ophthalmol 1997; 25(Suppl 1): 13-15.

32. Snow KK, Seddon JM. Age-Related Eye Disease. Int J Fertil 2000; 45(5): 301-313.

33. Vinding T. Age-related macular degeneration. Macular changes, prevalence and sex ratio. An epidemiological study of 1000 aged individuals. Acta Ophthalmol 1989; 67(6): 606-616.

34. Vingerling JR, Dielemans I, Witteman JCM et al. Macular degeneration and early menopause: a case control study. Br Med J 1995; 310: 1570-1571.

35. Zhengguong Ch, Molykutty J, Saradha S et al. 17beta-estradiol confers a protective effect against tansforming growth factor-beta2- induced cataract in female but not male lenses, Exp. Eye Research 2004; 78: 67-74.

Štítky
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine
Prihlásenie
Zabudnuté heslo

Zadajte e-mailovú adresu, s ktorou ste vytvárali účet. Budú Vám na ňu zasielané informácie k nastaveniu nového hesla.

Prihlásenie

Nemáte účet?  Registrujte sa

#ADS_BOTTOM_SCRIPTS#