The profile of tibolon with regard to breast safety in long-term therapy
Authors:
MUDr. Petrovičová Zuzana 1; prim. MUDr. Tibor Bielik; Ph.D. 2; MUDr. Milica Piškaninová 3
Authors place of work:
privátna gynekologická ambulancia
Banská Bystrica
1; gyn. -pôr. odd. FNsP FDR
Banská Bystrica
2; Organon, Bratislava
3
Published in the journal:
Prakt Gyn 2006; 10(3): 111-114
Summary
Hormonal substitution during menopause has a dramatic impact on the quality of life of women. Conventional hormonal therapy increases the incidence of mastodynia and MG density. Great stress is therefore laid on the selection of a preparation which has a minimum impact on MG density and on subjective feelings of patients when long-term use of hormone replacement therapy is necessary. The longitudinal retrospective study assessed 25 women taking tibolon for 36–119 months as compared with mammographic findings in women who had finished taking tibolon 36 months before. No difference was found between mammographic findings in women receiving long-term tibolon therapy and those in women who had finished taking tibolon. Tibolon appears to be a modality of postmenopause hormone replacement therapy which is well tolerated by patients even in cases where long-term therapy is necessary.
Key words:
tibolon – mammographic density – mastodynia
Zdroje
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Štítky
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicineČlánok vyšiel v časopise
Practical Gynecology
2006 Číslo 3
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