Chronic pain in interstitial cystitis
Authors:
MUDr. Libor Zámečník; Febu 1; prof. MUDr. Tomáš Hanuš, DrSc. 1,2
Authors place of work:
Urologická klinika VFN a 1. LF UK
1; Katedra urologie IPVZ Praha
2
Published in the journal:
Urol List 2007; 5(2): 41-47
Summary
Intersticial cystitis (IC) is a chronic, non-bacterial inflammatory disorder of the wall of the bladder manifested with very painful and unpleasant symptoms. It may resemble a bacterial inflammation of the urinary bladder, with no response to antibiotic treatment, however. The characteristic symptoms are: pain, urgent and frequent micturition. The pain is usually present in the hypogastrium and small pelvis, sometimes irradiating to the sacral area, vagina, groins and thighs (in men also to the penis, the testicles and the perineum). The urge of micturition is constant and typically persistent. This disorder prevailingly affects women (90 % of cases). About 10 % of patients with IC are men with previous wrongly diagnosed abacterial prostatitis or prostatodynia. IC can also be found in children. Treatment must be individual and also polypragmatic with regard to IC ethiopathogenesis. Response to treatment is highly individual and only a small part of therapeutic procedures can be declared curative. The authors summarise the available knowledge concerning the disorder, its diagnosing and treatment, and report their own experience with this nosologic unit and in the treatment of pain caused by IC..
Key words:
interstitial cystitis, pelvic pain syndrome, intravesical treatment
Zdroje
1. Hunner GL. A rare type of bladder ulcer in women: report of cases. Trans South Surg Gynecol Assoc 1915; 27: 247-292.
2. Oravisto KJ. Epidemiology of interstitial cystitis. Ann Chir Gynaecol Fenn 1975; 64: 75-77.
3. Clemens JQ, Meenan RT, Rosetti MC et al. Prevalence and incidence of interstitial cystitis in a managed care population. J Urol 2005; 173: 98-102.
4. Peeker R, Atanasiu L, Logadottir Y. Intercurrent autoimmune conditions in classic and non-ulcer interstitial cystitis. Scand J Urol Nephrol 2003; 37: 60-63.
5. Kanai A, de Groat W, Birder L et al. Symposium report on urothelial dysfunction: pathophysiology and novel therapies. J Urol 2006; 175: 1624-1629.
6. Anderson VR, Perry CM. Pentosan polysulfate: a review of its use in the relief of bladder pain or discomfort in interstitial cystitis. Drugs 2006; 66: 821-835.
7. Elbadawi A. Interstitial cystitis: a critique of current concepts with a new proposal for pathologic diagnosis and pathogenesis. Urology 1997; 49: 14-40.
8. Parsons M, Toozs-Hobson P. The investigation and management of interstitial cystitis. J Br Menopause Soc 2005; 11: 132-139.
9. Lotenfoe RR, Christie J, Parsons A et al. Absence of neuropathic pelvic pain and favorable psychological profile in the surgical selection of patients with disabling interstitial cystitis. J Urol 1995; 154: 2039-2042.
10. Kozák J, černý R, Vrba I. Neuropatická bolest z pohledu algeziologa. Neurol pro Praxi 2004; 7: 259-263.
11. Propert KJ, Mayer RD, Wang Y et al. Responsiveness of symptom scales for interstitial cystitis. Urology 2006; 67: 55-59.
12. Parsons CL, Stein PC, Bidair M, Lebow D. Abnormal sensitivity to intravesical potassium in interstitial cystitis and radiation cystitis. Neurourol Urodyn 1994; 13: 515-520.
13. Parsons CL, Albo M. Intravesical potassium sensitivity in patients with prostatitis. J Urol 2002; 168: 1054-1057.
14. Hohlbrugger G, Riedl CR. A new direct test of bladder permeability. J Urol 2001; 165: 914-915.
15. Zámečnik L, Hanuš T, Pavlík I et al. Interstitial cystitis-its diagnostics and treatment. čas Lék česk 2005; 144(suppl 2): 23-29.
16. Nordling J, Anjum FH, Bade JJ et al. Primary evaluation of patients suspected of having interstitial cystitis (IC). Eur Urol 2004; 45: 662-669.
17. Keay SK, Zhang CO, Shoenfelt J et al. Sensitivity and specificity of antiproliferative factor, heparin-binding epidermal growth factor-like growth factor, and epidermal growth factor as urine markers for interstitial cystitis. Urology 2001; 57: 9-14.
18. Clemons JL, Arya LA, Myers DL. Diagnosing interstitial cystitis in women with chronic pelvic pain. Obstet Gynecol 2002; 100: 337-341.
Štítky
Paediatric urologist UrologyČlánok vyšiel v časopise
Urological Journal
2007 Číslo 2
Najčítanejšie v tomto čísle
- CHRONIC PELVIC PAIN AND SEXUAL FUNCTIONS AS SEEN BY UROLOGIST AND ANATOMIST
- Chronic pain in interstitial cystitis
- PATHOPHYSIOLOGY OF PELVIC PAIN
- POSTOPERATIVE PAIN