WHAT POSSIBILITIES ARE CURRENTLY AVAILABLE AFTER RENAL CARCINOMA (ORGAN CONFINED) DIAGNOSTICS FAILURE?

Česká verzia

Authors: J. Katolická
Authors place of work: Onkologicko-chirurgické oddělení FN u svaté Anny, Brno
Published in the journal: Urol List 2011; 9(4): 39-42

Summary

Targeted therapy has recently become the skeleton of metastatic renal carcinoma treatment. The major agens for metastatic renal cancer treatment include sunitinib, temsirolimus, pazopanib and bevacizumab/INF as the first line therapy, and everolimus as the second line therapy (after VEGF-TKI inhibitor) and sorafenib (after cytokine therapy); however the optimal sequence of the individual medicaments has not been defined. All the medicaments are associated with specific side effects, therefore before initiating the treatment it is necessary to consider the clinical conditions of the patient, all comorbidities and the toxicity profile of given agens.

Key words:
metastatic renal carcinomatargeted therapy

Zdroje

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