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Localized renal tumour, epidemiology, aetiology, surgical treatment, operation techniques and their indications, the role of lymphadenectomy


Authors: P. Filipenský;  P. Řehořek;  Z. Oplatek;  R. Hrabec;  M. Krechlerová
Published in the journal: Urol List 2012; 10(3): 24-28

Summary

Renal adenocarcinomas [1] represent approximately 3% of all malignant tumours detected in adult population. Approximately 20% of patients [2] have metastases at the time of cancer diagnosis. Bilateral renal cancers are present in approximately 10% of patients. Adenocarcinomas occur 1,5times more often in males [2]. The availability of ultrasound examination has led to an increase in diagnostics of clinically asymptomatic renal cancers. It should be noted that early diagnosis and treatment of renal cancer increa­ses the chance of cure. In case the tumour is detected in its early stage the cancer specific survival (CSS) ranges from 79 to 100%. Approximately 85–92% of expansive renal processes are malignant; the most common type is the conventional renal carcinoma (90%). It is primarily growing from the cell of proximal tubule [10]. Renal tumours classification is based on the 2004 TNM classification and pathological classification is based on the 1997 Heidelberg classification of renal neoplasia.

Key words:
kidney tumour, kidney resection, nephrectomy


Zdroje

1. American Cancer Society. Cancer Facts and Figures 2012. Atlanta, Ga: American Cancer Society, 2012.

2. www.svod.cz

3. Thoenes W, Storkel S, Rumpelt HJ et al. Cyto­morpho­logical typing of renal cell carcinoma – a new approach. Eur Urol 1990; 18 (Suppl 2): 6–9.

4. Kovacs G, Akhtar M, Beckwith BJ et al. The Heidel­berg classification of renal cell tumours. J Pathol 1997; 183(2): 131–133.

5. Latif F, Duh FM, Gnarra J et al. von Hippel-Lindau syndrome: cloning and identification of the plasma membrane Ca(++)-transporting ATPase isoform 2 gene that resides in the von Hippel-Lindau gene region. Cancer Res 1993; 53(4): 861–867.

6. Lendvay TS, Marshall FF. The tuberous sclerosis complex and its highly variable manifestations. J Urol 2003; 169(5): 1635–1642.

7. Bonné AC, Bodmer D, Schoenmakers EF et al. Chro­mosome 3 translocations and familial renal cell cancer. Curr Mol Med 2004; 4(8): 849–854.

8. Woodward ER. Familial non-syndromic clear cell re­nal cell carcinoma. Curr Mol Med 2004; 4(8): 843–848.

9. Schmidt L, Duh FM, Chen F et al. Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas. Nat Genet 1997; 16(1): 68–73.

10. Nickerson ML, Warren MB, Toro JR et al. Muta­tions in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dube syndrome. Cancer Cell 2002; 2(2): 157–164.

11. Cheville JC, Blute ML, Zincke H et al. Stage pT1 conventional (clear cell) renal cell carcinoma: pathological features associated with cancer specific survival. J Urol 2001; 166(2): 453–456.

12. Grignon DJ, Che M. Clear cell renal cell carcinoma. Clin Lab Med 2005; 25(2): 305–316.

13. Algaba F, Trias I, Scarpelli M et al. Handling and pathology reporting of renal tumor specimens. Eur Urol 2004; 45(4): 437–443.

14. Van Poppel H. Conservative vs radical surgery for renal cell carcinoma. BJU Int 2004; 94(6): 766–748.

15. Kim SP, Thompson RH, Boorijan SA et al. Com­parative Effectiveness for Survival and Renal Function of Partial and Radical Nephrectomy for Localized Re­nal Tumors: A Systematic Review and Meta-Ana­lysis. J Urol 2012; 188(1): 51–57.

16. Kim SP, Leibovich BC, Shah ND et al. The relationship of postoperative complications with in-hospital outcomes and costs after renal surgery for kidney cancer. BJU Int 2012; Epub ahead of print.

17. Marszalek M, Ponholzer A, Brossner C et al. Elec­tive open nephron sparin Sumery for renal masses: single – center experience with 129 consecutive patiens. Urology 2004; 64(1): 38–42.

18. Eret V, Hora M et al. Současné možnosti mini­invazivní léčby nádorů ledvin. Praha: Galén 2011; 100 s., příloha DVD (7 videí).

Štítky
Paediatric urologist Urology
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