Selective estrogen receptor modulators and the management of male hypoandrogenism – a systematic analysis
Authors:
M. Kathrins; H. Wadhwa; C. Niederberger
Authors place of work:
University of Pennsylvania Medical Center
Published in the journal:
Urol List 2015; 13(3): 22-26
Summary
Selective estrogen receptor modulators, such as clomiphene citrate, have been used as an off-label treatment of hypoandrogenism and idiopathic male infertility for over 30 years. We performed a systematic analysis of selective estrogen receptor modulators use in men with hypoandrogenism to examine issues related to dosage, hormonal and symptomatic efficacy, and adverse events. Our analysis indicates that treatment is well-tolerated and efficacious when compared to traditional exogenous testosterone supplementation. However the ideal dosage of clomiphene citrate has yet to be elucidated. We also provide a review of our institutional practices on the use and safety monitoring of clomiphene citrate.
Key words:
clomiphene citratemale infertility hypoandrogenism selective estrogen receptor modulators hormonal therapy
Zdroje
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Štítky
Paediatric urologist UrologyČlánok vyšiel v časopise
Urological Journal
2015 Číslo 3
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