The importance of antimicrobial prophylaxis on urgent appendectomy
Authors:
Jakub Jandík
Authors place of work:
Chirurgické oddělení, Oblastní nemocnice Rychnov nad Kněžnou a. s.
Published in the journal:
Hojení ran 7, č. 2: 3-6, 2013
Category:
Summary
Introduction:
Prophylactic antibiotics administration before surgery evidently decreases surgical site infections incidence. Antimicrobial prophylaxis guideline was installed on author´s workplace in 2011. In 2012 we demanded consistently compliance of this guideline especially given to time interval of administration in the same time with premedication ordered by anesthetist, it means 30–60 minutes before surgery.
Target:
Evaluation of surgical site infections incidence after appendectomy as model surgical procedure in dependence to antimicrobial prophylaxis.
Method:
Retrospective analysis of file of 134 patients operated in 24 hours after admission to hospital for suspected acute appendicitis and comparison results with previous years.
Results:
Consistent compliance to antimicrobial prophylaxis guideline including time interval of admission in 94,8 % of patients led to significant decrease of surgical site infections from 7,74 % in 2011 to 0,7 % in 2012.
Conclusion:
Consistent compliance to antimicrobial prophylaxis guideline led in model surgery procedure to significant decrease of surgical site infections incidence. As the most important factor of efficiency appears the time interval of admission 30–60 minutes before surgery starts.
Key words:
acute appendicitis, antimicrobial prophylaxis, surgical site infections
Zdroje
Andersen, B. R., Kallehave, F. L., Andersen, H. K. Antibiotics versus placebo for prevention of postoperative infection after appendicectomy. Cochrane Database Syst Rev 3: CD001439, 2005.
Bratzler, D. W., Houck, P. M., Richards, C. et al. Use of antimicrobial prophylaxis for major surgery: baseline results from the National Surgical Infection Prevention project. Arch Surg 140, 2: 174–182, 2005.
Centers for Disease Control. Infection Control in Healthcare Settings. Dostupné z: http://www.cdc.gov/ncidod/dhqp (DCC 2009)
Centers for Medicare and Medicaid Services. QualityNet. Dostupné z: http://www.qualitynet.org (CMMS 2009)
Craig, S. Acute Appendicitis. eMedicine Apr. 12th 2010.
Cruse, P. J., Foord, R. The epidemiology of wound infection. A 10-year prospective study of 62,939 wounds. Surg Clin North Am 60, 1: 27–40, 1980.
Finklestein, R., Reinhertz, G., Embom, A. Surveillance of the use of antibiotic prophylaxis in surgery. Isr J Med Sci 32, 11: 1093–1097, 1996.
Furnary, A. P., Zerr, K. J., Grunkemeier, G. L., Starr, A. Continuous intravenous insulin infusion reduces the incidence of deep sternal wound infection in diabetic patients after cardiac surgical procedures. Ann Thorac Surg 67, 2: 352–360, 1999.
Greif, R., Akca, O., Horn, E. P. et al. for the outcomes research group. Supplemental perioperative oxygen to reduce the incidence of surgical wound infection. N Engl J Med 342, 2: 161–167, 2000.
Jandík, J. Akutní apendicitis – přehled současných poznatků. Rozhl Chir 90, 10: 568–574, 2011.
Jandík, J. Akutní apendicitis – ranné komplikace a význam antibiotické profylaxe. Rozhl Chir 90, 7: 408–413, 2011.
Kirkland, K. B., Briggs, J. P., Trivette, S. L. et al. The impact of surgical-site infections in the 1990s: attributable mortality, excess lenght od hospitalization, and extra costs. Infect Control Hosp Epidemiol 20, 11: 725–730, 1999.
Knighton, D. R., Halliday, B., Hunt, T. K. Oxygen as an antibiotic. A comparison of the effects of inspired oxygen concentration and antibiotic administration on in vivo bacterial clearance. Arch Surg 121, 2: 191–195, 1986.
Kurz, A., Sessler, D. I., Lenhardt, R. Perioperative normothermia to reduce the incidence of surgical wound-infection and shorten hospitalization. Study of Wound Infection and Temperature Group. N Engl J Med 334, 19: 1209–1215, 1996.
Lee, S. L., Shekgerdimian, S. Vermiform Appendix. eMedicine Specialities, General Surgery. Update Nov. 24th 2008.
Lizán-García, M., García-Caballero, J., Asensio-Vegas, A. Risk factors for surgical wound infection in general surgery: a prospective study. Infect Control Hosp Epidemiol 18, 5: 310–315, 1997.
Mangram, A. J., Horan, T. C., Pearson, M. L. et al. Guideline for prevention of surgical site infections, 1999. Hospital Infection Control Practices Advisory Commitee. Infect Control Hosp Epidemiol 20, 4: 247–275, 1999.
Mazzioti, M. V., Minkes, R. K. Appendicitis, Surgical Treatment. eMedicine, General Surgery. Update Nov. 12th 2008.
Meyhoff, C. S., Wetterslev, J., Jorgensen, L. N. et al. Effect of high perioperative oxygen fraction on surgical site infection and pulmonary complications after abdominal surgery: the PROXI randomized clinical trial. JAMA 302, 14: 1543–1550, 2009.
Santacroce, L., Ochoa, J. B. Appendicitis. eMedicine Specialites, General Surgery. MedScape, Update Apr. 20th 2010.
Sauerland, S., Lefering, R., Neugebauer, E. A. Laparoscopic versus open surgery for suspected appendicitis. Cochrane Database Syst Rev 4: CD001546, 2004.
Shuhatovich, Y., Zuniga, M. R. et al. Appendectomy, Laparoscopic. MedScape, General Surgery, Updated Aug 20th 2010.
Silver, A., Eichorn, A., Kral, J. Timeliness and use of antibiotic prophylaxis in selected inpatient surgical procedures. The Antibiotic Prophylaxis Study Group. Am J Surg 171, 6: 548–552, 1996.
Singhal, H., Kaur, K. Wound Infection. eMedicine Specialities, General Surgery. Update Sep. 15th 2009.
Uckay, I., Harbarth, S., Peter, R. et al. Preventing surgical site infections. Expert Rev Anti Infect Ther 8, 6: 657–670, 2010.
van den Berghe, G., Wouters, P., Weekers, F. et al. Intensive insulin therapy in critically ill patients. N Engl J Med 345, 19: 1359–1367, 2001.
Woods, R. K., Dellinger, E. P. Current guidelines for antibiotic prophylaxis of surgical wounds. Am Fam Physician 57, 11: 2731–2740, 1998.
Štítky
Surgery Nurse Home nurseČlánok vyšiel v časopise
Wound Healing
2013 Číslo 2
- Spasmolytic Effect of Metamizole
- Metamizole at a Glance and in Practice – Effective Non-Opioid Analgesic for All Ages
- Metamizole in perioperative treatment in children under 14 years – results of a questionnaire survey from practice
- Current Insights into the Antispasmodic and Analgesic Effects of Metamizole on the Gastrointestinal Tract
- Obstacle Called Vasospasm: Which Solution Is Most Effective in Microsurgery and How to Pharmacologically Assist It?
Najčítanejšie v tomto čísle
- The complex regional pain syndrome in a wound treatment
- The importance of antimicrobial prophylaxis on urgent appendectomy
- Cellulose materials in the wound healing
- Perinatal traumatism