#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Potential anticancer agent hypericin and its model compound emodin: interaction with DNA


Autoři: Jana Staničová 1,2;  Valéria Verebová 1;  Alena Strejčková 1
Působiště autorů: The University of Veterinary Medicine & Pharmacy, Košice, Slovakia 1;  First Faculty of Medicine, Charles University, Prague, Czech Republic 2
Vyšlo v časopise: Čes. slov. Farm., 2016; 65, 28-31
Kategorie: 44<sup>th</sup> Conference drug synthesis and analysis

*Part 1: Čes. slov. Farm. 2015; 64, 200–225.
*Part 2: Čes. slov. Farm. 2015; 64, 269–304.


Zdroje

1. Lopez-Bazzocchi I., Hudson J. B., Towers G. H. N. Antiviral activity of the photoactive plant pigment hypericin. Photochem. Photobiol. 1991; 54, 95–98.

2. Andreoni A., Colasanti A., Colasanti P., Mastrocinque M., Riccio P., Roberti G. Laser photosensitization of cells by hypericin. Photochem. Photobiol. 1994; 59, 529–533.

3. Miškovský P. Hypericin – A new antiviral and antitumor photosensitizer: mechanism of action and interaction with biological macromolecules. Current Drug Targets 2002; 3, 55–84.

4. Dougherty T. J., Gomer C. J., Henderson B. W., Jori G., Kessel D., Korbelik M., Peng Q. J. Photodynamic therapy. Natl. Cancer Inst. 1998; 90, 889–905.

5. Kiesslich T., Krammer B., Plaetzer K. Cellular mechanisms and prospective applications of hypericin in photodynamic therapy. Curr. Med. Chem. 2006; 13, 2189–20201.

6. Karioti A., Bilia A. R. Hypericins as potential leads for new therapeutics. Int. J. Mol. Sci. 2010; 11, 562–594.

7. Radovic J., Maksimovic-Ivanic D., Timotijevic G., Popadic S., Ramic Z., Trajkovic V., Miljkovic D., Stosic-Grujicic S., Mijatovic S. Cell-type dependent response of melanoma cells to aloe emodin. Food and chemical toxicology 2012; 50(9), 3181–3189.

8. Poliaček I., Stránsky A., Jakuš J., Baráni H., Tomori Z., Halašová E. Activity of the laryngeal abductor and adductor muscles during cough, expiration and aspiration reflexes in cats. Physiological Research 2003; 52(6), 749–762.

9. Copeland R. A. Enzymes – a practical introduction to structure, mechanism, and data analysis. 2nd edition. New York – Chichester – Weinheim – Brisbane – Singapore – Toronto: John Wiley & Sons INC 2000.

10. Ciolkowski M. L., Fang M. M., Lund M. E. A surface plasmon resonance method for detecting multiple modes of DNA-ligand interactions. J. Pharm. Biomed. Anal. 2000; 22, 6.

11. Agarwal S., Jangir D. K., Mehrotra R. Spectroscopis studies of the effects of anticancer drug mitoxantrone interaction with calf-thymus DNA. J. Photochem. Photobiol. B 2013; 120, 177–182.

12. Gholivand M. B., Kashanian S., Peyman H., Roshanfekr H. DNA-binding study of anthraquinone derivatives using Chemometrics methods. European Journal of Medicinal Chemistry 2011; 46, 2630–2638.

13. Verebová V., Adamčík J., Danko P., Podhradský D., Miškovský P., Staničová J.Anthraquinones quinizarin and danthron unwind negatively supercoiled DNA and lengthen linear DNA. Biochemical and Biophysical Research Communication 2014; 444, 50–55.

14. Kočišová E., Chinsky L., Miškovský P. Sequence specific interaction of the photoactive drug hypericin depends on the structural arrangement and the stability of the structure containing its specific 5 ‘ AG3 ‘ target: A resonance Raman spectroscopy study J. Biomol. Structure Dynamics 1999; 17(1), 51–59.

15. Kumar C. V., Turner R. S., Asuncion E. H. Groove binding of astyrylcyanine dye to the DNA double helix: the salt effect. Journal of Photochemistry and Photobiology A: Chemistry 1993; 74(2–3), 231–238.

16. Bi S., Zhang H., Qiao C., Sun Y., Liu C. Studies of interaction of emodin and DNA in the presence of ethidium bromide by spectroscopic method. Spectrochimica Acta A: Mol. Biomol. Spectrosc. 2008; 69(1), 123–129.

17. Lavery R., Pullman, B. Molecular electrostatic potential on the surface envelopes of macromolecules: B-DNA. International Journal of Quantum Chemistry 1981; 20(1), 259–272.

18. Shahabadi N., Heidari L. Binding studies of the antidiabetic drug, metformin to calf thymus DNA using multispectroscopic methods. Spectrochimica Acta A: Mol. Biomol. Spectrosc. 2012; 97, 406–410.

Štítky
Farmácia Farmakológia

Článok vyšiel v časopise

Česká a slovenská farmacie

Číslo 1

2016 Číslo 1

Najčítanejšie v tomto čísle
Kurzy

Zvýšte si kvalifikáciu online z pohodlia domova

Aktuální možnosti diagnostiky a léčby litiáz
nový kurz
Autori: MUDr. Tomáš Ürge, PhD.

Všetky kurzy
Prihlásenie
Zabudnuté heslo

Zadajte e-mailovú adresu, s ktorou ste vytvárali účet. Budú Vám na ňu zasielané informácie k nastaveniu nového hesla.

Prihlásenie

Nemáte účet?  Registrujte sa

#ADS_BOTTOM_SCRIPTS#