19th Annual Meeting of the European Society for Pediatric Clinical Research (ES-PCR)

Bratislava, Slovakia
June 24–26, 2010

Scientific Program

June 25, 2010

• 8.30–10.00

ORAL PRESENTATIONS 1

Chair: Ľudmila Podracká, Tivadar Tulassay

1. (*) Renal transplantation in atypical HUS. Riedl M., Hofer J., Rosales A., Yeutukhova Y., Jungraithmayr T., Zimmerhackl L. B. (Innsbruck)
2. Cardiac magnetic resonance imaging (MR) in children with chronic kidney disease and renal transplantation. Schäfer B., Rusai K., Tóth A., Krekó M., Horváth E., Sallay P., Reusz G. S., Merkely B., Tulassay T., Szabó A. J. (Budapest)
3. The correlation between genotype and phenotype in autosomal dominant polycystic kidney disease (ADPKD) in children. Fencl F., Štekrová J., Bláhová K., Janda J., Seeman T. (Praha)
4. Differentiation of proteinuria in focal segmental glomerulosclerosis using proteomics-analysis. Lackner S., Zimmerhackl L. B., Mischak H., Toenshoff B., Bjerre A., Seeman T., Dötsch J., Jungraithmayr T. C. (Innsbruck)
5. MTHFR gene polymorphism C677T is associated with urinary tract anomalies in girls – sex differences related to methylation? Behunová J., Klimčáková L., Podracká Ľ. (Košice)
6. Toll-like receptor 4 polymorphism is associated with increased risk of urinary tract infection in girls above age 2. Jankó V., Pozsgayová S., Podracká Ľ., Kovács L. (Bratislava)

• 10.00–10.30 COFFEE BREAK

• 10.30-12.00

ORAL PRESENTATIONS 2

Chair: Andrea Heinzmann, Jan Janda

1. (*) Differential methylation in cord blood T-lymphocytes of children prenatally exposed to tobacco smoke compared to controls and risk for asthma. Grychtol R., Heinzmann A., Kreutz C. (Freiburg)
2. (*) Lymphocyte calcium influx characteristics and their modulation by Kv1.3 and IKca1 channel inhibitors in the neonate. Toldi G., Mészáros G., Treszl A., Tulassay T., Vásárhelyi B. (Budapest)
3. Cough characteristics in asthmatic children. Jesenak M., Banovcin P. (Martin)
4. (*) Prophylaxis against birch pollen allergy by neonatal colonization with a Lactobacillus plantarum producing the major birch pollen allergen Bet v 1. Repa A., Schwarzer M., Schabussova I., Daniel C., Hrnčíř T., Pot B., Štěpánková R., Hudcovic T., Pollak A., Tlaskalová-Hogenová H. , Wiedermann U., Kozáková H. (Vienna)
5. Use of the new Amplatzer duct occluder II in comparison with the Amplatzer duct occluder – single centre experience. Venczelová Z., Tittel P., Mašura J. (Bratislava)

• 12.00–13.00 LUNCH

• 13.00–14.00

POSTER PRESENTATIONS – A

Chair: Hana Hrstková, László Kovács, György Reusz

1. (*) Epidemiology of end-stage renal disease in Slovak children. Koľvek G., Reijneveld S. A., Podracká Ľ., Rosenberger J., Van Dijk J. P. (Košice)
2. Shigatoxin and complement activation are toxic to human podocytes. Dettmar A., Binder E., Feifel E., Gstraunthaler G., Karch H., Zimmerhackl L. B. (Innsbruck)
3. Hemolytic Uremic Syndrome associated to sorbitol fermenting O157:H^- Shiga toxin producing Escherichia coli. Rosales A., Hofer J., Riedl M., Jungraithmayr T. C., Würzner R., Karch H., Zimmerhackl L. B. (Innsbruck)
4. Pulse wave velocity and intima-media thickness in renal transplant children. Kerti A., Kis É., Cseprekál O., Horváth T., Szabó A. J., Kollai M., Tulassay T., Reusz S. Gy. (Budapest)
5. The role of bioimpedance analysis in the diagnosis of malnutrition in chronically ill children. Svekusova M., Podracká Ľ. (Košice)
6. Pretreatment plasma folate modulates the pharmacodynamics effect of systemic mtx in children with nhl and all: („folate over rescue“) concept revisited. Bernatiková H., Valik D., Dubská L., Ruzičková P., Domanský J., Krenová Z., Mendelová D., Sterba J. (Brno)
7. (*) Clinical relevance of GGH-401C>T and RFC1 A(80)G polymorphism in treatment of osteosarcoma in childhood. Hegyi M. Z., Semsei Á.F., Cságoly E., Erdélyi D., Szalai C., Kovács G. (Budapest)
8. Transient myeloproliferative disease in children with Down syndrome mosaic. Kolenová A., Reinhardt K., Nathrat M., Rössig C., Pekrun A., Neuhoff C., Reinhardt D. (Bratislava)
9. Parallel development of doxorubicin and paclitaxel resistant cell lines to establish a model for independently evolving resistance. Tegze B., Munkácsy G., Pénzváltó Z., Győrffy B. (Budapest)
10. (*) Molecular analysis of the NF1 gene in a group of Slovak patients. Rybárová A., Nemethová M., Ilenčiková D., Hlinková K., Hlavatá A., Kovács L., Kadasi L., Zaťková A. (Bratislava)
11. Effect of anthracycline therapy on baroreflex sensitivity in children and adolescents between 11 to 20 years. Šťastná J., Hrstková H., Nováková Z., Honzíková N., Fišer B., Závodná E. (Brno)

POSTER PRESENTATIONS – B

Chair: Susanne Greber-Platzer, Magdalena Riedl, András Szabó

1. TLR2 and TLR4 polymorphisms in Kawasaki disease. Kitzmüller E., Sadhegi K., Dangl A., Herkner K., Förster-Waldl E., Greber-Platzer S. (Vienna)
2. (*) Lack of specificity of immunoglobulin D for hyper-IgD syndrome. Dallos T., Hlavatá A., Paulovičová E., Baldovič M., Fehérvízyová Z., Kovács L. (Bratislava)
3. Cardiovascular disease in Turner syndrome. Klásková E., Zapletalová J., Wiedermann J., Sobek A. (Olomouc)
4. (*) Joint influences of interleukin 4 and 13 with acidic-mammalian-chitinase in the genetics of asthma. Heinzmann A., Brugger M., Grychtol R., Strauch K. (Freiburg)
5. Comparing the quality of neurally adjusted ventilation assist versus conventional ventilation support in children with acute lung injury. Fremuth J., Sasek L., Pizingerová K., Vrzalová J., Topolčan O., Kobr J. (Plzeň)
6. The use of a EEG monitoring in assessment of short–term and long-term neurological outcome in neonates with perinatal asphyxia. Lukášková J., Kokštein Z., Kubinová H. (Hradec Kralove)
7. Role of autoantibodies and cytokines in prediction of diabetes type 1. Petruzelková L., Stechová K., Siftancová J., Hubačková M., Staviková V., Lebl J., Kolousková S. (Praha)
8. Prometheus in hepatal failure. Nowaková M., Hladík M., Zaoral T. (Ostrava)
9. (*) Decreased expression of intestinal alkaline phosphatase (iAP) in the colonic mucosa of paediatric IBD patients. Molnar K., Vannay A., Szebeni B., Arató A., Györffy H., Sziksz E., Nagy-Szakál D., Cseh A., Bánki N. F., Tulassay T., Dezsőfi A., Veres G. (Budapest)
10. Azathioprine treatment and TPMT polymorphisms in pediatric patients with inflammatory bowel disease. Dzurenková A., Šoltysová A., Čierna I., Minárik G., Kovács L., Mladosievičová B. (Bratislava)
11. Haptoglobin polymorphism in children with type 1 diabetes mellitus and with diabetes and coeliac disease. Nagy-Szakál D., Papp M., Körner A., Pályu E., Molnár K., Dezsőfi A., Arató A., Veres G. (Budapest)
12. Mutational analysis of MC4R gene in obese children in Slovakia. Vitáriušová E. , Polák E., Kúseková M., Pribilincová Z., Košťálová Ľ., Hlavatá A., Tichá Ľ., Kádaši Ľ., Kovács L. (Bratislava)

• 14.00–14.30 COFFEE BREAK

• 14.30–16.00

ORAL PRESENTATIONS 3

Chair: Tadej Avčín, Jiři Zeman

1. (*) Clinical characteristics and molecular analysis of 37 Central and East-European patients with chronic granulomatous disease. Markelj G., Debeljak M., Pašić S., Čižnár P., Janda A., Poloučková A., Freiberger T., Šedivá A., Avčin T. (Ljubljana)
2. Monogenic diabetes type mody in Slovakia: results of a nation-wide survey. Staník J., Gašperíková D., Hučková M., Valentínová L., Barák Ľ., Kúseková M., Šandriková V., Javorková J., Mašindová I., Michálek J., Slovak Monogenic Diabetes Study Group, Klimeš I. (Bratislava)
3. Alterations of bone metabolic parameters in children and adolescents with chronic myeloid leukemia (CML) under prolonged treatment with the tyrosine kinase inhibitor imatinib. Tauer J. T., Jaeger B. A. S., Suttorp M. (Dresden)
4. Knockdown of cytochrome c oxidase structural subunits in HEK293 cells. Fornusková D., Zeman J. (Praha)

STATE-OF-ART LECTURE

Chair: Radvan Urbanek

Gene manipulations in deciphering pathogenesis of birth defects. Dudáš M. (Košice)

• 16.00–16.30 COFFEE BREAK

• 16.30–18.00

ORAL PRESENTATIONS 4

Chair: Gábor Kovács, Vladimír Mihal

1. (*)MicroRNA expression analysis in human lymphoma/leukemia cells. Nemes K., Márk Á., Hajdu M., Csorba G., Kopper L., Sebestyén A., Csóka M. (Budapest)
2. Molecular principle of corticoid´s effect in childhood acute lymphoblastic leukemia. Mihal V., Spenerová M., Koudelaková V., Benediková A., Ruzková V., Srovnal J., Hajduch M. (Olomouc)
3. Tyrosine kinase receptors in pediatric brain tumors. Virág J., Tímár J., Hegedűs B., Garam M. (Budapest)
4. (*) Defined markers for detection of germ cells at risk for malignant transformation in patients with disorders of sex development. Pleskacová J., Stoop H., Oosterhuis J.., Cools M., Lau Y. F. Ch., Drop S. L. S., Šnajderová M., Lebl J., Looijenga L. H. J. (Praha)
5. Developing a bio-informatic tool for the preliminary assessment of cancer biomarkers using publicly available microarray datasets. Györffy B., Lanczky A., Szallasi Z. (Budapest)

• 18.00 – CONCLUDING REMARKS – BEST PRESENTATION & BEST POSTER AWARDS

LEGEND: (*) presentation/poster was granted by „AWARD OF EXCELLENCE“