It's All in the Timing: Too Much E2F Is a Bad Thing
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Vyšlo v časopise:
It's All in the Timing: Too Much E2F Is a Bad Thing. PLoS Genet 8(8): e32767. doi:10.1371/journal.pgen.1002909
Kategorie:
Perspective
prolekare.web.journal.doi_sk:
https://doi.org/10.1371/journal.pgen.1002909
Souhrn
article has not abstract
Zdroje
1. BiswasAK, JohnsonDG (2012) Transcriptional and nontranscriptional functions of E2F1 in response to DNA damage. Cancer Res 72(1) 13–17.
2. StevensC, La ThangueNB (2004) The emerging role of E2F-1 in the DNA damage response and checkpoint control. DNA Repair (Amst) 3(8–9): 1071–1079.
3. AsanoM, NevinsJR, WhartonRP (1996) Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginal discs. Genes Dev 10(11): 1422–32.
4. ShibutaniS, SwanhartLM, DuronioRJ (2007) Rbf1-independent termination of E2f1-target gene expression during early Drosophila embryogenesis. Development 134: 467–478.
5. ShibutaniST, de la CruzAF, TranV, TurbyfillWJ3rd, ReisT, et al. (2008) Intrinsic negative cell cycle regulation provided by PIP box- and Cul4Cdt2-mediated destruction of E2f1 during S phase. Dev Cell 15(6): 890–900.
6. DavidsonJM, DuronioRJ (2012) S phase-coupled E2f1 destruction ensures homeostasis in proliferating tissues. PLoS Genet 8(8): e1002831 doi:10.1371/journal.pgen.1002831.
7. Tanaka-MatakatsuM, XuJ, ChengL, DuW (2009) Regulation of apoptosis of rbf mutant cells during Drosophila development. Dev Biol 326(2): 347–356.
8. MoonNS, Di StefanoL, MorrisEJ, PatelR, WhiteK, et al. (2008) E2F and p53 induce apoptosis independently during Drosophila development but intersect in the context of DNA damage. PLoS Genet 4(8): e1000153 doi:10.1371/journal.pgen.1000153.
9. KrekW, XuG, LivingstonDM (1995) Cyclin A-kinase regulation of E2F1 DNA binding function underlies suppression of an S-phase checkpoint. Cell 83(7): 1149–1158.
10. CampaneroMR, FlemingtonEK (1997) Regulation of E2F through ubiquitin-proteasome-dependent degradation: stabilization by the pRB tumor suppressor protein. Proc Natl Acad Sci U S A 94(6): 2221–2226.
Štítky
Genetika Reprodukčná medicínaČlánok vyšiel v časopise
PLOS Genetics
2012 Číslo 8
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