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Why Are tRNAs Overproduced in the Absence of Maf1, a Negative Regulator of RNAP III, Not Fully Functional?


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Vyšlo v časopise: Why Are tRNAs Overproduced in the Absence of Maf1, a Negative Regulator of RNAP III, Not Fully Functional?. PLoS Genet 11(12): e32767. doi:10.1371/journal.pgen.1005743
Kategorie: Perspective
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pgen.1005743

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Zdroje

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7. Kramer EB, Hopper AK (2013) Retrograde transfer RNA nuclear import provides a new level of tRNA quality control in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 110:21042–7. doi: 10.1073/pnas.1316579110 24297920

8. Gustavsson M, Ronne H (2008) Evidence that tRNA modifying enzymes are important in vivo targets for 5-fluorouracil in yeast. RNA 14: 666–674. doi: 10.1261/rna.966208 18314501

9. Steinberg S, Cedergren R (1995) A correlation between N2-dimethylguanosine presence and alternate tRNA conformers. RNA 1:886–891. 8548653

10. Begley U, Dyavaiah M, Patil A, Rooney JP, DiRenzo D, Young CM, Conklin DS, Zitomer RS, Begley TJ (2007) Trm9-catalyzed tRNA modifications link translation to the DNA damage response. Mol Cell 28: 860–870 18082610

11. Fernandez-Vazgues J, Vargas-Pérez I, Sansó M, Buhne K, Carmona M, Paulo E, Hermand D, Rodríguez-Gabriel M, Ayté J, Leidel S, Hidalgo E (2013) Modification of tRNA(Lys) UUU by elongator is essential for efficient translation of stress mRNAs. PLoS Genet 9(7):e1003647. doi: 10.1371/journal.pgen.100364 23874237

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Štítky
Genetika Reprodukčná medicína

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PLOS Genetics


2015 Číslo 12
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Autori: MUDr. Tomáš Ürge, PhD.

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