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Monitoring Pharmacologically Induced Immunosuppression by Immune Repertoire Sequencing to Detect Acute Allograft Rejection in Heart Transplant Patients: A Proof-of-Concept Diagnostic Accuracy Study


A novel, proof-of-concept, diagnostic test for allograft rejection. The authors use a barcode-sequencing approach to determine the isotypes and clonal composition of circulating B cells in heart transplant patients.


Vyšlo v časopise: Monitoring Pharmacologically Induced Immunosuppression by Immune Repertoire Sequencing to Detect Acute Allograft Rejection in Heart Transplant Patients: A Proof-of-Concept Diagnostic Accuracy Study. PLoS Med 12(10): e32767. doi:10.1371/journal.pmed.1001890
Kategorie: Research Article
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pmed.1001890

Souhrn

A novel, proof-of-concept, diagnostic test for allograft rejection. The authors use a barcode-sequencing approach to determine the isotypes and clonal composition of circulating B cells in heart transplant patients.


Zdroje

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Interné lekárstvo

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PLOS Medicine


2015 Číslo 10
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