The Cost-Effectiveness of Low-Cost Essential Antihypertensive Medicines for Hypertension Control in China: A Modelling Study

1. Yang G, Wang Y, Zeng Y, Gao GF, Liang X, et al. (2013) Rapid health transition in China, 1990–2010: findings from the Global Burden of Disease Study 2010. Lancet 381: 1987–2015. doi: 10.1016/S0140-6736(13)61097-1 23746901

2. Wang J, Zhang L, Wang F, Liu L, Wang H, et al. (2014) Prevalence, awareness, treatment, and control of hypertension in China: results from a national survey. Am J Hypertens 27: 1355–1361. doi: 10.1093/ajh/hpu053 24698853

3. Yu B, Zhang X, Wang G (2013) Full coverage for hypertension drugs in rural communities in China. Am J Manag Care 19: e22–29. 23379776

4. Zhang M, Meng Y, Yang Y, Liu Y, Dong C, et al. (2011) Major inducing factors of hypertensive complications and the interventions required to reduce their prevalence: an epidemiological study of hypertension in a rural population in China. BMC Public Health 11: 301. doi: 10.1186/1471-2458-11-301 21569365

5. Tang JL, Wang WZ, An JG, Hu YH, Cheng SH, et al. (2010) How willing are the public to pay for anti-hypertensive drugs for primary prevention of cardiovascular disease: a survey in a Chinese city. Int J Epidemiol 39: 244–254. doi: 10.1093/ije/dyp213 19491141

6. Yip WC, Hsiao WC, Chen W, Hu S, Ma J, et al. (2012) Early appraisal of China's huge and complex health-care reforms. Lancet 379: 833–842. doi: 10.1016/S0140-6736(11)61880-1 22386036

7. Tang S, Tao J, Bekedam H (2012) Controlling cost escalation of healthcare: making universal health coverage sustainable in China. BMC Public Health 12 Suppl 1: S8. doi: 10.1186/1471-2458-12-S1-S8 22992484

8. Moran A, Gu D, Zhao D, Coxson P, Wang YC, et al. (2010) Future cardiovascular disease in china: markov model and risk factor scenario projections from the coronary heart disease policy model-china. Circ Cardiovasc Qual Outcomes 3: 243–252. doi: 10.1161/CIRCOUTCOMES.109.910711 20442213

9. Wang M, Moran AE, Liu J, Coxson PG, Heidenreich PA, et al. (2014) Cost-effectiveness of optimal use of acute myocardial infarction treatments and impact on coronary heart disease mortality in China. Circ Cardiovasc Qual Outcomes 7: 78–85. doi: 10.1161/CIRCOUTCOMES.113.000674 24425706

10. Liu LS, Writing Group of Chinese Guidelines for the Management of Hypertension (2011) [2010 Chinese guidelines for the management of hypertension]. Zhonghua Xin Xue Guan Bing Za Zhi 39: 579–615. 22088239

11. Mancia G, Fagard R, Narkiewicz K, Redon J, Zanchetti A, et al. (2013) 2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J 34: 2159–2219. doi: 10.1093/eurheartj/eht151 23771844

12. Lozano R, Murray C.J.L., Lopez A.D., and Satoh T. (2001) Miscoding and misclassification of ischaemic heart disease mortality. Global Programme on Evidence for Health Policy Working Paper No. 12. Geneva, World Health Organization.

13. Liu J, Hong Y, D'Agostino RB Sr., Wu Z, Wang W, et al. (2004) Predictive value for the Chinese population of the Framingham CHD risk assessment tool compared with the Chinese Multi-Provincial Cohort Study. JAMA 291: 2591–2599. 15173150

14. Law MR, Morris JK, Wald NJ (2009) Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies. BMJ 338: b1665. doi: 10.1136/bmj.b1665 19454737

15. Law MR, Wald NJ, Morris JK, Jordan RE (2003) Value of low dose combination treatment with blood pressure lowering drugs: analysis of 354 randomised trials. BMJ 326: 1427. 12829555

16. Turnbull F, Blood Pressure Lowering Treatment Trialists Collaboration (2003) Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials. Lancet 362: 1527–1535. 14615107

17. Lewington S, Clarke R, Qizilbash N, Peto R, Collins R (2002) Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 360: 1903–1913. 12493255

18. Moran AE, Odden MC, Thanataveerat A, Tzong KY, Rasmussen PW, et al. (2015) Cost-effectiveness of hypertension therapy according to 2014 guidelines. N Engl J Med 372: 447–455. doi: 10.1056/NEJMsa1406751 25629742

19. (2009) The Ministry of Health of the People's Republic of China. China's Health Statistics Yearbook 2009. Beijing: the Peking Union Medical College Press

20. Huffman MD, Rao KD, Pichon-Riviere A, Zhao D, Harikrishnan S, et al. (2011) A cross-sectional study of the microeconomic impact of cardiovascular disease hospitalization in four low- and middle-income countries. PLoS One 6: e20821. doi: 10.1371/journal.pone.0020821 21695127

21. (2011) CHOosing Interventions that are Cost Effective (WHO-CHOICE). World Health Organization.

22. Salomon JA, Vos T, Hogan DR, Gagnon M, Naghavi M, et al. (2012) Common values in assessing health outcomes from disease and injury: disability weights measurement study for the Global Burden of Disease Study 2010. Lancet 380: 2129–2143. doi: 10.1016/S0140-6736(12)61680-8 23245605

23. Hellermann JP, Goraya TY, Jacobsen SJ, Weston SA, Reeder GS, et al. (2003) Incidence of heart failure after myocardial infarction: is it changing over time? Am J Epidemiol 157: 1101–1107. 12796046

24. Yusuf S, Islam S, Chow CK, Rangarajan S, Dagenais G, et al. (2011) Use of secondary prevention drugs for cardiovascular disease in the community in high-income, middle-income, and low-income countries (the PURE Study): a prospective epidemiological survey. Lancet 378: 1231–1243. doi: 10.1016/S0140-6736(11)61215-4 21872920

25. Vrijens B, Vincze G, Kristanto P, Urquhart J, Burnier M (2008) Adherence to prescribed antihypertensive drug treatments: longitudinal study of electronically compiled dosing histories. BMJ 336: 1114–1117. doi: 10.1136/bmj.39553.670231.25 18480115

26. Weinstein MC, Siegel JE, Gold MR, Kamlet MS, Russell LB (1996) Recommendations of the Panel on Cost-effectiveness in Health and Medicine. JAMA 276: 1253–1258. 8849754

27. Lim SS, Gaziano TA, Gakidou E, Reddy KS, Farzadfar F, et al. (2007) Prevention of cardiovascular disease in high-risk individuals in low-income and middle-income countries: health effects and costs. Lancet 370: 2054–2062. 18063025

28. James PA, Oparil S, Carter BL, Cushman WC, Dennison-Himmelfarb C, et al. (2014) 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA 311: 507–520. doi: 10.1001/jama.2013.284427 24352797

29. Li Y, Ying C, Sufang G, Brant P, Bin L, et al. (2013) Evaluation, in three provinces, of the introduction and impact of China's National Essential Medicines Scheme. Bull World Health Organ 91: 184–194. doi: 10.2471/BLT.11.097998 23476091

30. Johns B, Baltussen R, Hutubessy R (2003) Programme costs in the economic evaluation of health interventions. Cost Eff Resour Alloc 1: 1. 12773220

31. Bai Y, Zhao Y, Wang G, Wang H, Liu K, et al. (2013) Cost-effectiveness of a hypertension control intervention in three community health centers in China. J Prim Care Community Health 4: 195–201. doi: 10.1177/2150131912470459 23799707

32. Wang X, Li W, Li X, An N, Chen H, et al. (2013) Effects and cost-effectiveness of a guideline-oriented primary healthcare hypertension management program in Beijing, China: results from a 1-year controlled trial. Hypertens Res 36: 313–321. doi: 10.1038/hr.2012.173 23154592

33. Liang XH, Gu DF, Zhang H, Zhu K, Deng Y, et al. (2011) [The analysis of drug cost and direct medical expense in community health management of hypertensive patients]. Zhonghua Yu Fang Yi Xue Za Zhi 45: 732–736. 22169696

34. Husereau D, Drummond M, Petrou S, Carswell C, Moher D, et al. (2013) Consolidated Health Economic Evaluation Reporting Standards (CHEERS) statement. BMJ 346: f1049. doi: 10.1136/bmj.f1049 23529982

35. Anderson JL, Heidenreich PA, Barnett PG, Creager MA, Fonarow GC, et al. (2014) ACC/AHA statement on cost/value methodology in clinical practice guidelines and performance measures: a report of the American College of Cardiology/American Heart Association Task Force on Performance Measures and Task Force on Practice Guidelines. Circulation 129: 2329–2345. doi: 10.1161/CIR.0000000000000042 24677315

36. Rodgers A, Lawes CMM, Gaziano T, Vos T (2006) The Growing Burden of Risk from High Blood Pressure, Cholesterol, and Bodyweight. In: Jamison DT, Breman JG, Measham AR, Alleyne G, Claeson M, Evans DB, Jha P, Mills A, Musgrove P., editor. Disease Control Priorities in Developing Countries. New York: Oxford University Press and the World Bank.

37. Wang H, Yip W, Zhang L, Wang L, Hsiao W (2005) Community-based health insurance in poor rural China: the distribution of net benefits. Health Policy Plan 20: 366–374. 16143589

38. Niu S, Zhao D, Zhu J, Liu J, Liu Q, et al. (2009) The association between socioeconomic status of high-risk patients with coronary heart disease and the treatment rates of evidence-based medicine for coronary heart disease secondary prevention in China: Results from the Bridging the Gap on CHD Secondary Prevention in China (BRIG) Project. Am Heart J 157: 709–715 e701. doi: 10.1016/j.ahj.2008.12.009 19332200