Associations between an IgG3 polymorphism in the binding domain for FcRn, transplacental transfer of malaria-specific IgG3, and protection against malaria during infancy: A birth cohort study in Benin
In a birth cohort study in Benin, Celia Dechavanne and colleagues examines associations between the IgG3-H435 variant, transplacental transfer of malaria-specific IgG3, and protection against Plasmodium falciparum malaria during infancy.
Vyšlo v časopise:
Associations between an IgG3 polymorphism in the binding domain for FcRn, transplacental transfer of malaria-specific IgG3, and protection against malaria during infancy: A birth cohort study in Benin. PLoS Med 14(10): e32767. doi:10.1371/journal.pmed.1002403
Kategorie:
Research Article
prolekare.web.journal.doi_sk:
https://doi.org/10.1371/journal.pmed.1002403
Souhrn
In a birth cohort study in Benin, Celia Dechavanne and colleagues examines associations between the IgG3-H435 variant, transplacental transfer of malaria-specific IgG3, and protection against Plasmodium falciparum malaria during infancy.
Zdroje
1. World Health Organization. World Malaria Report 2016. Geneva: World Health Organization; 2016 [cited 2017 Mar 17]. Available from: http://www.who.int/malaria/publications/world-malaria-report-2016/report/en/.
2. Murungi LM, Sondén K, Odera D, Oduor LB, Guleid F, Nkumama IN, et al. Cord blood IgG and the risk of severe Plasmodium falciparum malaria in the first year of life. Int J Parasitol. 2017;47(2–3):153–62. doi: 10.1016/j.ijpara.2016.09.005 27890694
3. Abdullah S, Adazu K, Masanja H, Diallo D, Hodgson A, Ilboudo-Sanogo E, et al. Patterns of age-specific mortality in children in endemic areas of sub-Saharan Africa. Am J Trop Med Hyg. 2007;77:99–105.
4. Dobbs KR, Dent A. Plasmodium malaria and antimalarial antibodies in the first year of life. Parasitology. 2016;143:129–38. doi: 10.1017/S0031182015001626 26743626
5. Stapleton NM, Andersen JT, Stemerding AM, Bjarnarson SP, Verheul RC, Gerritsen J, et al. Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential. Nat Commun. 2011;2:599. doi: 10.1038/ncomms1608 22186895
6. Mathiesen L, Nielsen LK, Andersen JT, Grevys A, Sandlie I, Michaelsen TE, et al. Maternofetal transplacental transport of recombinant IgG antibodies lacking effector functions. Blood. 2013;122:1174–81. doi: 10.1182/blood-2012-12-473843 23843496
7. Kana IH, Adu B, Tiendrebeogo RW, Singh SK, Dodoo D, Theisen M. Naturally acquired antibodies target the glutamate-rich protein on intact merozoites and predict protection against febrile malaria. J Infect Dis. 2017;215(4):623–30. doi: 10.1093/infdis/jiw617 28329101
8. Simister NE. Placental transport of immunoglobulin G. Vaccine. 2003;21:3365–9. 12850341
9. Palmeira P, Quinello C, Silveira-Lessa AL, Zago CA, Carneiro-Sampaio M. IgG placental transfer in healthy and pathological pregnancies. Clin Dev Immunol. 2012;2012:985646. doi: 10.1155/2012/985646 22235228
10. Oganesyan V, Damschroder MM, Cook KE, Li Q, Gao C, Wu H, et al. Structural insights into neonatal Fc receptor-based recycling mechanisms. J Biol Chem. 2014;289:7812–24. doi: 10.1074/jbc.M113.537563 24469444
11. Jensen PF, Larraillet V, Schlothauer T, Kettenberger H, Hilger M, Rand KD. Investigating the interaction between the neonatal Fc receptor and monoclonal antibody variants by hydrogen/deuterium exchange mass spectrometry. Mol Cell Proteomics. 2015;14:148–61. doi: 10.1074/mcp.M114.042044 25378534
12. Shields RL, Namenuk AK, Hong K, Meng YG, Rae J, Briggs J, et al. High resolution mapping of the binding site on human IgG1 for FcγRI, FcγRII, FcγRIII, and FcRn and design of IgG1 variants with improved binding to the FcγR. J Biol Chem. 2001;276:6591–604. doi: 10.1074/jbc.M009483200 11096108
13. Ward ES, Ober RJ. Chapter 4: multitasking by exploitation of intracellular transport functions the many faces of FcRn. Adv Immunol. 2009;103:77–115. doi: 10.1016/S0065-2776(09)03004-1 19755184
14. Spiegelberg HL. Biological activities of immunoglobulins of different classes and subclasses. Adv Immunol. 1974;19:259–94. 4611173
15. Medesan C, Matesoi D, Radu C, Ghetie V, Ward ES. Delineation of the amino acid residues involved in transcytosis and catabolism of mouse IgG1. J Immunol. 1997;158:2211–7. 9036967
16. Stapleton NM, Einarsdóttir HK, Stemerding AM, Vidarsson G. The multiple facets of FcRn in immunity. Immunol Rev. 2015;268:253–68. doi: 10.1111/imr.12331 26497526
17. Dechavanne C, Guillonneau F, Chiappetta G, Sago L, Lévy P, Salnot V, et al. Mass spectrometry detection of G3m and IGHG3 alleles and follow-up of differential mother and neonate IgG3. PLoS ONE. 2012;7(9):e46097. doi: 10.1371/journal.pone.0046097 23049948
18. Lefranc M-P, Lefranc G. Human Gm, Km, and Am allotypes and their molecular characterization: a remarkable demonstration of polymorphism. Methods Mol Biol. 2012;882:635–80. doi: 10.1007/978-1-61779-842-9_34 22665258
19. Einarsdottir H, Ji Y, Visser R, Mo C, Luo G, Scherjon S, et al. H435-containing immunoglobulin G3 allotypes are transported efficiently across the human placenta: implications for alloantibody-mediated diseases of the newborn. Transfusion. 2014;54:665–71. doi: 10.1111/trf.12334 23829325
20. Le Port A, Cottrell G, Chandre F, Cot M, Massougbodji A, Garcia A. Importance of adequate local spatiotemporal transmission measures in malaria cohort studies: application to the relation between placental malaria and first malaria infection in infants. Am J Epidemiol. 2013;178:136–43. doi: 10.1093/aje/kws452 23752916
21. Damien GB, Djènontin A, Rogier C, Corbel V, Bangana SB, Chandre F, et al. Malaria infection and disease in an area with pyrethroid-resistant vectors in southern Benin. Malar J. 2010;9:380. doi: 10.1186/1475-2875-9-380 21194470
22. Le Port A, Cottrell G, Martin-Prevel Y, Migot-Nabias F, Cot M, Garcia A. First malaria infections in a cohort of infants in Benin: biological, environmental and genetic determinants. Description of the study site, population methods and preliminary results. BMJ Open. 2012;2:e000342. doi: 10.1136/bmjopen-2011-000342 22403339
23. Cottrell G, Kouwaye B, Pierrat C, le Port A, Bouraïma A, Fonton N, et al. Modeling the influence of local environmental factors on malaria transmission in Benin and its implications for cohort study. PLoS ONE. 2012;7(1):e28812. doi: 10.1371/journal.pone.0028812 22238582
24. Dechavanne C, Sadissou I, Bouraima A, Ahouangninou C, Amoussa R, Milet J, et al. Acquisition of natural humoral immunity to P. falciparum in early life in Benin: impact of clinical, environmental and host factors. Sci Rep. 2016;6:33961. doi: 10.1038/srep33961 27670685
25. R Core Team. R: a language and environment for statistical computing. Version 3.1.3. Vienna: R Foundation for Statistical Computing; 2015. Available from: http://www.R-project.org/.
26. Dambrun M, Dechavanne C, Emmanuel A, Aussenac F, Leduc M, Giangrande C, et al. Human immunoglobulin heavy gamma chain polymorphisms: molecular confirmation of proteomic assessment. Mol Cell Proteomics. 2017;16(5):824–39. doi: 10.1074/mcp.M116.064733 28265047
27. Adu B, Cherif MK, Bosomprah S, Diarra A, Arthur FKN, Dickson EK, et al. Antibody levels against GLURP R2, MSP1 block 2 hybrid and AS202.11 and the risk of malaria in children living in hyperendemic (Burkina Faso) and hypo-endemic (Ghana) areas. Malar J. 2016;15:123. doi: 10.1186/s12936-016-1146-4 26921176
28. Kapur R, Einarsdottir HK, Vidarsson G. IgG-effector functions: “the good, the bad and the ugly.” Immunol Lett. 2014;160:139–44. doi: 10.1016/j.imlet.2014.01.015 24495619
29. Vidarsson G, Dekkers G, Rispens T. IgG subclasses and allotypes: from structure to effector functions. Front Immunol. 2014;5:520. doi: 10.3389/fimmu.2014.00520 25368619
30. Richards JS, Stanisic DI, Fowkes FJI, Tavul L, Dabod E, Thompson JK, et al. Association between naturally acquired antibodies to erythrocyte-binding antigens of Plasmodium falciparum and protection from malaria and high-density parasitemia. Clin Infect Dis. 2010;51:e50–60. doi: 10.1086/656413 20843207
31. Teo A, Feng G, Brown GV, Beeson JG, Rogerson SJ. Functional antibodies and protection against blood-stage malaria. Trends Parasitol. 2016;32:887–98. doi: 10.1016/j.pt.2016.07.003 27546781
32. Boyle MJ, Reiling L, Feng G, Langer C, Osier FH, Aspeling-Jones H, et al. Human antibodies fix complement to inhibit Plasmodium falciparum invasion of erythrocytes and are associated with protection against malaria. Immunity. 2015;42:580–90. doi: 10.1016/j.immuni.2015.02.012 25786180
33. Beeson JG, Drew DR, Boyle MJ, Feng G, Fowkes FJI, Richards JS. Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria. FEMS Microbiol Rev. 2016;40:343–72. doi: 10.1093/femsre/fuw001 26833236
34. Bruhns P, Iannascoli B, England P, Mancardi DA, Fernandez N, Jorieux S, et al. Specificity and affinity of human Fcgamma receptors and their polymorphic variants for human IgG subclasses. Blood. 2009;113:3716–25. doi: 10.1182/blood-2008-09-179754 19018092
35. International Genome Sample Source. IGSR and the 1000 Genomes Project. 2017 [cited 2017 Aug 29]. Available from: http://www.internationalgenome.org/.
36. Vettermann C, Schlissel MS. Allelic exclusion of immunoglobulin genes: models and mechanisms. Immunol Rev. 2010;237:22–42. doi: 10.1111/j.1600-065X.2010.00935.x 20727027
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