Practice guideline and trends for immunosuppressive treatment of glomerulonephritides according to KDIGO (Clinical Practice Guideline for Glomerulonephritis)

Česká verzia

Authors: Ľ. Podracká ¹; K. Matoušovic ²
Authors place of work: I. klinika detí a dorastu Lékárskej fakulty UPJŠ a DFN Košice, Slovenská republika, prednostka prof. MUDr. Ľudmila Podracká, CSc. ¹; Interní klinika 2. lékařské fakulty UK a FN Motol Praha, přednosta prof. MUDr. Milan Kvapil, CSc., MBA ²
Published in the journal: Vnitř Lék 2013; 59(2): 113-118
Category: Přehledný referát

Motto: Je doba svítání v mnoha otázkách aetiologie a pathogenesy nefritid – a tím i doba důležitého vyjasňování v indikacích therapeutických. (prof. Pelnář, Nemoc Brightova, Spolek lékařů českých, 1932)

Summary

We summarize recommendations for glomerulonephritis treatment, established by internationally recognized experts in the field and sponsored by KDIGO (Kidney Disease Improving Global Outcomes). Up till now, the KDIGO review has been the most prestigious analysis of therapeutic trials on immunosuppressive treatment of glomerulonephritides. The 167 recommendations addresses the following forms of glomerulopathies: steroid-sensitive nephrotic syndrome and steroid resistant nephrotic syndrome in children; minimal change disease and idiopathic focal segmental glomerulosclerosis in children and adults; idiopathic membranous nephropathy; idiopathic membranoproliferative glomerulonephritis; glomerulonephritis associated with infection; immunoglobulin A nephropathy and Henoch-Schönlein purpura nephritis; lupus nephritis; pauci-immune focal and segmental necrotizing glomerulonephritis; and anti--glomerular basement membrane antibody glomerulonephritis. We focuse our attention on progress in this topic in the last decade.

Key words:
glomerulonephritis – treatment – immunosuppression

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