Use of albumin in perioperative and intensive care medicine

Česká verzia

Authors: D. Astapenko ^1,2; J. Pouska ^3,4; J. Škola ^2,5; J. Beneš ^2,5; J. Náhlovský ^2,6; M. Mynář ^1,2; Z. Turek ^1,2; J. Beneš ^3,4; V. Černý ^1,2,5,7,8
Authors place of work: Klinika anesteziologie, resuscitace a intenzivní medicíny, Fakultní nemocnice Hradec Králové ¹; Lékařská fakulta v Hradci Králové, Univerzita Karlova ²; Klinika anesteziologie, resuscitace a intenzivní medicíny, Fakultní nemocnice Plzeň ³; Lékařská fakulta v Plzni, Univerzita Karlova ⁴; Klinika anesteziologie, perioperační a intenzivní medicíny, Univerzita J. E. Purkyně v Ústí nad Labem, Masarykova nemocnice v Ústí nad Labem ⁵; Dětská klinika, Fakultní nemocnice Hradec Králové ⁶; Centrum pro výzkum a vývoj, Fakultní nemocnice Hradec Králové ⁷; Department of Anesthesia, Pain Management and Perioperative Medicine, Dalhousie University, Halifax, Nova Scotia, Canada ⁸
Published in the journal: Anest. intenziv. Med., 31, 2020, č. 3, s. 96-102
Category: Review Articles

Summary

Albumin is still a widely studied protein of the human body. Historically, it has been infused as a volume replacement using its oncotic properties. In the field of fluid therapy in recent years, it has been compared with other types of solutions in various clinical indications and its safety was monitored. Another subject of research is its other biological effects, which are used in specific clinical situations: liver failure, prevention of acute renal failure, adult acute respiratory distress syndrome, traumatic brain injury, ovarian hyperstimulation syndrome. The review article summarizes the current state of knowledge and its use in adult patients in intensive care as well as in neonatology. It also discusses selected clinical syndromes and the hitherto known physiology of albumin in the human body. It also deals with the use of albumin in extracorporeal support of organ functions: extracorporeal circulation in the cardiac surgery, dialysis and plasmapheresis.

Keywords:

shock – liver failure – fluid therapy – albumin – acute respiratory distress syndrome in adults

Zdroje

1. Vincent JL. Relevance of albumin in modern critical care medicine. Best Pract Res Clin Anaesthesiol. 2009; 23(2): 183–191.

2. Vincent J‑L, Russell JA, Jacob M, Martin G, Guidet B, Wernerman J, et al. Albumin administration in the acutely ill: what is new and where next? Crit Care BioMed Central Ltd. 2014; 18(4): 231.

3. Quinlan GJ, Martin GS, Evans TW. Albumin: Biochemical properties and therapeutic potential. Hepatology 2005; 41(6): 1211–1219.

4. Waijer SW, Gansevoort RT, Heerspink HJL. Change in albuminuria as a surrogate endpoint. Curr Opin Nephrol Hypertens 2019; 28(6): 519–526.

5. Artigas A, Wernerman J, Arroyo V, Vincent JL, Levy M. Role of albumin in diseases associated with severe systemic inflammation: Pathophysiologic and clinical evidence in sepsis and in decompensated cirrhosis. J Crit Care 2016; 33: 62–70.

6. Delgado‑Rodríguez M, Cuadros MM, Ortega AG, Galego‑Martínez G, Mariscal‑Ortiz M, Martinez‑Gonzalez MA, et al. Cholesterol and serum albumin levels as predictors of cross infection, death, and length of hospital stay. Arch Surg American Medical Association 2002; 137(7): 805–812.

7. Bascom JU, Gosling P, Zikria BA. Hypoalbuminemia, surgical leak, and clinical capillary leak syndrome. Arch Surg 2000; 135(1): 95.

8. Vink H, Duling BR. Capillary endothelial surface layer selectively reduces plasma solute distribution volume. Am J Physiol Heart Circ Physiol 2000; 278(1): H285–H289.

9. Mitzner S, Stange J, Klammt S, Peszinsky P, Hickstein H, Korten G, et al. Albumin‑bound substances‑a new target in liver failure therapy. Z Gastroenterol 2001; 39(Suppl 2): 6–7.

10. Dasgupta A. Usefulness of monitoring free (unbound) concentrations of therapeutic drugs in patient management. Clin Chim Acta 2007; 377(1–2): 1–13.

11. Contreras AM, Ramírez M, Cueva L, Alvarez S, de Loza R, Gamba G. Low serum albumin and the increased risk of amikacin nephrotoxicity. Rev Invest Clin 1994; 46(1): 37–43.

12. Stamler JS, Jaraki O, Osborne J, Simon DI, Keaney J, Vita J, et al. Nitric oxide circulates in mammalian plasma primarily as an S‑nitroso adduct of serum albumin. Proc Natl Acad Sci U S A 1992; 89(16): 7674–7677.

13. Arroyo V, García‑Martinez R, Salvatella X. Human serum albumin, systemic inflammation, and cirrhosis. J Hepatol 2014; 61(2): 396–407.

14. Pathirana S, Wong G, Williams P, Yang K, Kershaw G, Dunkley S, et al. The effects of haemodilution with albumin on coagulation in vitro as assessed by rotational thromboelastometry. Anaesth Intensive Care 2015; 43(2): 187–192.

15. Fransson F, Kyrk T, Skagerlind M, Stegmayr B. Rinsing the extra corporeal circuit with a heparin and albumin solution reduces the need for systemic anticoagulant in hemodialysis. Int J Artif Organs 2013; 36(10): 725–729.

16. Montomoli J, Donati A, Ince C. Should Albumin be the Colloid of Choice for Fluid Resuscitation in Hypovolemic Patients? Annual Update in Intensive Care and Emergency Medicine 2019: 277–292.

17. Tabor E. The epidemiology of virus transmission by plasma derivatives: Clinical studies verifying the lack of transmission of hepatitis B and C viruses and HIV type 1. Transfusion. 1999; 39(11–12): 1160–1168.

18. Fanali G, Masi A Di, Trezza V, Marino M, Fasano M, Ascenzi P. Human serum albumin: From bench to bedside. Mol Aspects Med. 2012; 33(3): 209–290.

19. Finfer S, Bellomo R, Boyce N, French J, Myburgh J, Norton R, et al. A Comparison of Albumin and Saline for Fluid Resuscitation in the Intensive Care Unit. N Engl J Med 2004; 350(22): 2247–2256.

20. Mårtensson J, Bihari S, Smith JB, Glassford NJ, Lloyd‑Donald P, Cioccari L, et al. Small volume resuscitation with 20 % albumin in intensive care: physiological effects The SWIPE randomised clinical trial. Intensive Care Med. 2018; 44(11): 1797–1806.

21. Winters ME, Sherwin R, Vilke GM, Wardi G. What is the Preferred Resuscitation Fluid for Patients with Severe Sepsis and Septic Shock? J Emerg Med 2017; 53(6): 928–939.

22. Gleeson MW, Dickson RC. Albumin gains immune boosting credibility. Clin Transl Gastroenterol American College of Gastroenterology 2015; 6(4): e86.

23. Malbrain MLNG, Regenmortel N Van, Saugel B, De Tavernier B, Van Gaal PJ, Joannes‑Boyau O, et al. Principles of fluid management and stewardship in septic shock: it is time to consider the four D’s and the four phases of fluid therapy. Ann Intensive Care SpringerOpen 2018; 8(1): 66.

24. Vincent J‑L, Navickis RJ, Wilkes MM. Morbidity in hospitalized patients receiving human albumin: a meta‑analysis of randomized, controlled trials. Crit Care Med 2004; 32(10): 2029–2038.

25. Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. Intensive Care Med 2017; 43(3): 304–377.

26. Uchimido R, Schmidt EP, Shapiro NI. The glycocalyx: a novel diagnostic and therapeutic target in sepsis. Crit Care 2019; 23(1): 16.

27. Vincent JL, Backer D De, Wiedermann CJ. Fluid management in sepsis: The potential beneficial effects of albumin. J Crit Care 2016; 35: 161–167.

28. Siddall E, Khatri M, Radhakrishnan J. Capillary leak syndrome: etiologies, pathophy‑ siology, and management. Kidney Int 2017; 92(1): 37–46.

29. Santos F, Arroyo C, García I, Blasco R, Obispo JM, Hamann C, et al. Role of mast cells in the pathogenesis of postburn inflammatory response: reactive oxygen species as mast cell stimulators. Burns 2000; 26(2): 145–147.

30. Demling RH. The burn edema process: Current concepts. J Burn Care Rehabil 2005; 26(3): 207–227.

31. Vlachou E, Gosling P, Moiemen NS. Microalbuminuria: A marker of endothelial dysfunction in thermal injury. Burns 2006; 32(8): 1009–1016.

32. Goodwin CW, Dorethy J, Lam V, Pruitt Jr. BA. Randomized Trial of Efficacy of Crystalloid and Colloid Resuscitation on Hemodynamic Response and Lung Water Following Thermal Injury. Ann Surg 1983; 197(5): 520–531.

33. Paine CH, Biggins SW, Pichler RH. Albumin in Cirrhosis: More Than a Colloid. Curr Treat Options Gastroenterol. 2019; 17(2): 231–243.

34. Hoeboer SH, Oudemans‑van Straaten HM, Groeneveld ABJ. Albumin rather than C‑reactive protein may be valuable in predicting and monitoring the severity and course of acute respiratory distress syndrome in critically ill patients with or at risk for the syndrome after new onset fever. BMC Pulm Med BioMed Central 2015; 15: 22.

35. National Heart, Lung and BIARDS (ARDS) CTN, Wiedemann HP, Wheeler AP, Bernard GR, Thompson BT, Hayden D, et al. Comparison of Two Fluid‑Management Strategies in Acute Lung Injury. N Engl J Med 2006; 354(24): 2564–2575.

36. Martin GS, Moss M, Wheeler AP, Mealer M, Morris JA, Bernard GR. A randomized, controlled trial of furosemide with or without albumin in hypoproteinemic patients with acute lung injury. Crit Care Med 2005; 33(8): 1681–1687.

37. Uhlig C, Silva PL, Deckert S, Schmitt J, de Abreu MG. Albumin versus crystalloid solutions in patients with the acute respiratory distress syndrome: a systematic review and meta‑analysis. Crit Care BioMed Central 2014; 18(1): R10.

38. Torer B, Hanta D, Yapakci E, Gokmen Z, Parlakgumus A, Gulcan H, et al. Association of Serum Albumin Level and Mortality in Premature Infants. J Clin Lab Anal John Wiley and Sons Inc. 2016; 30(6): 867–872.

39. Shalish W, Olivier F, Aly H, Sant’Anna G. Uses and misuses of albumin during resuscitation and in the neonatal intensive care unit. Semin Fetal Neonatal Med 2017; 22(5): 328–335.

40. Jardine LA, Jenkins‑Manning S, Davies MW. Albumin infusion for low serum albumin in preterm newborn infants. Cochrane database Syst Rev 2004; (3): CD004208.

41. Gantner D, Moore EM, Cooper DJ. Intravenous fluids in traumatic brain injury: what’s the solution? 2014; 385–389.

42. Nordström C‑H. Physiological and Biochemical Principles Underlying Volume‑Targeted Therapy - The „Lund Concept“. Neurocritical Care 2005; 2: 83–95.

43. Cooper DJ, Myburgh J, Heritier S, Finfer S, Bellomo R, Billot L, et al. Albumin Resuscita‑ tion for Traumatic Brain Injury: Is Intracranial Hypertension the Cause of Increased Mortality? 2013; 518: 512–518.

44. Xu J‑Y, Chen Q‑H, Xie J‑F, Pan C, Liu SQ, Huang LW, et al. Comparison of the effects of albumin and crystalloid on mortality in adult patients with severe sepsis and septic shock: a meta‑analysis of randomized clinical trials. Crit Care BioMed Central 2014; 18(6): 702.

45. Jacob M, Paul O, Mehringer L, Chappell D, Rehm M, Welsch U, et al. Albumin Augmentation Improves Condition of Guinea Pig Hearts After 4 hr of Cold Ischemia. Transplantation 2009; 87(7): 956–965.

46. Wiedermann CJ, Wiedermann W, Joannidis M. Hypoalbuminemia and acute kidney injury: a meta‑analysis of observational clinical studies. Intensive Care Med 2010; 36(10): 1657–1665.

47. Wiedermann CJ, Joannidis M. Nephroprotective Potential of Human Albumin Infusion: A Narrative Review. Gastroenterol Res Pract 2015; 2015: 912839.

48. Youseff MA, Mourad S. Volume expanders for the prevention of ovarian hyperstimulation syndrome. Cochrane Database of Systematic Reviews 2016; 8: CD001302.

49. Patel J, Prajapati M, Solanki A, Pandya H. Comparison of albumin, Hydroxyethyl starch and ringer lactate solution as priming fluid for cardiopulmonary bypass in paediatric cardiac surgery. J Clin Diagnostic Res Journal of Clinical and Diagnostic Research 2016; 10(6): UC01–UC04.

50. Maleki MH, Derakhshan P, Sharifabad AR, Amouzeshi A. Comparing the effects of 5% albumin and 6% hydroxyethyl starch 130/0.4 (Voluven) on renal function as priming solutions for cardiopulmonary bypass: A randomized double blind clinical trial. Anesthesiol Pain Med Kowsar Medical Publishing Company 2016; 6(1): 1–6.

51. Wigmore GJ, Anstey JR, St John A, Greaney J, Morales‑Codina M, Presneill JJ, et al. 20% Human Albumin Solution Fluid Bolus Administration Therapy in Patients After Cardiac Surgery (the HAS FLAIR Study). J Cardiothorac Vasc Anesth 2019; 33(11): 2920–2927.

52. Sangalli F, Patroniti N, Pesenti A. ECMO‑Extracorporeal Life Support in Adults. 2014. Springer [on‑line] [cit. 2019]. Dostupné z: https://www.springer.com/gp/book/9788847054264.

53. Dzierba AL, Abrams D, Brodie D. Medicating patients during extracorporeal membrane oxygenation: The evidence is building. Critical Care 2017 [on‑line]. BioMed Central Ltd. 2017.

54. Wengenmayer T, Schroth F, Biever PM, Duerschmied D, Benk Ch, Trummer G, et al. Albumin fluid resuscitation in patients on venoarterial extracorporeal membrane oxygenation (VA‑ECMO) therapy is associated with improved survival. Intensive Care Med. 2018; 44(12): 2312–2314.

55. Nakanishi T, Suzuki N, Kuragano T, Nagasawa Y, Hasuike Y. Current topics in therapeutic plasmapheresis. Clin Exp Nephrol 2014; 18(1): 41–49. 56. Tsipotis E, Shuja A, Jaber BL. Albumin Dialysis for Liver Failure: A Systematic Review. Adv Chronic Kidney Dis 2015; 22(5): 382–390.