Pictures of plaques and fixed drug combination for better cardiovascular prevention

Česká verzia

Authors: Jan Piťha
Authors place of work: Interní klinika FN Motol a Centrum experimentální medicíny IKEM, Praha
Published in the journal: AtheroRev 2018; 3(3): 192-196
Category: Reviews

Summary

In the majority of patients, the risk of cardiovascular events can be reduced by appropriate outpatient care. Nevertheless, in common practice, significant proportion of patients are still left at rather high risk because of insufficient management due to inappropriately cautious approach of some physicians and not ideal cooperation of substantial proportion of patients. Challenging field of atherosclerosis research is its detection by non-invasive methods especially in asymptomatic persons. While still mainly area of interesting research, it could become one of main contributions in improving patients‘ cooperation. Specifically, patients are informed about the presence of atherosclerotic changes presented by imaging methods (sonographic pictures of the plaques in carotid and femoral arteries, or by increased calcium score of coronary arteries detected by computed tomography). Combination of this approach with fixed combination of antihypertensive and hypolipidemic drugs in one tablet could become a very potent tool how to improve patient adherence to therapy and lifestyle changes.

Key words:

compliance to therapy, imaging methods, preclinical atherosclerosis, fixed combinations of drugs

Received: 21. 9. 2018

Accepted: 1. 10. 2018

Zdroje

SCORE algoritmus pro výpočet desetileté pravděpodobnosti fatální kardiovaskulární příhody založený na Weibullově modelu. Dostupné z WWW: <https://www.ikem.cz/cs/score-algoritmus-pro-vypocet-desetilete-pravdepodobnosti-fatalni-kardiovaskularni-prihody-zalozeny-na-weibullove-modelu/a-2177>.
Estruch R, Ros, E, Salas-Salvadó J et al. [PREDIMED Study Investigators]. Primary prevention of cardiovascular disease with a Mediterranean diet. N Engl J Med 2013; 368(14): 1279–1290. Dostupné z DOI: <http://dx.doi.org/10.1056/NEJMoa1200303>. Erratum in N Engl J Med 2014; 370(9): 886.
Keith M, Kuliszewski MA, Liao C et al. A modified portfolio diet complements medical management to reduce cardiovascular risk factors in diabetic patients with coronary artery disease. Clin Nutr 2015; 34(3): 541–548. Dostupné z DOI: <http://dx.doi.org/10.1016/j.clnu.2014.06.010>.
Collins R, Reith C, Emberson J et al. Interpretation of the evidence for the efficacy and safety of statin therapy. Lancet 2016; 388(10059): 2532–2561. Dostupné z DOI: <http://dx.doi.org/10.1016/S0140–6736(16)31357–5>. Erratum in Department of Error. [Lancet. 2017].
Ambrose JA, Barua RS. The pathophysiology of cigarette smoking and cardiovascular disease: an update. J Am Coll Cardiol 2004; 43(10): 1731–1737. Dostupné z DOI: <http://dx.doi.org/10.1016/j.jacc.2003.12.047>.
Catapano AL, Graham I, De Backer G et al. [ESC Scientific Document Group]. 2016 ESC/EAS Guidelines for the Management of Dyslipidaemias. Eur Heart J 2016; 37(39): 2999–3058. Dostupné z DOI: <http://dx.doi.org/10.1093/eurheartj/ehw272>.
Vrablík M, Piťha J, Bláha Vl et al. Stanovisko výboru České společnosti pro aterosklerózu k doporučením ESC/EAS pro diagnostiku a léčbu dyslipidemií z roku 2016. AtheroRev 2017; 2(3): 185–193.
Cournot M, Bura A, Cambou JP et al. Arterial ultrasound screening as a tool for coronary risk assessment in asymptomatic men and women. Angiology 2012; 63(4): 282–288. Dostupné z DOI: <http://dx.doi.org/10.1177/0003319711414865>.
Griffin M, Nicolaides A, Tyllis T et al. Carotid and femoral arterial wall changes and the prevalence of clinical cardiovascular disease. Vasc Med 2009; 14(3): 227–232. Dostupné z DOI: <http://dx.doi.org/10.1177/1358863X08101542>.
Hecht HS. Coronary artery calcium scanning: past, present, and future. JACC Cardiovasc Imaging 2015; 8(5): 579–596. Dostupné z DOI: <http://dx.doi.org/10.1016/j.jcmg.2015.02.006>.
Zaid M, Fujiyoshi A, Kadota A et al. Coronary Artery Calcium and Carotid Artery Intima Media Thickness and Plaque: Clinical Use in Need of Clarification. J Atheroscler Thromb 2017; 24(3): 227–239. Dostupné z DOI: <http://dx.doi.org/10.5551/jat.RV16005>.
Rodondi N, Collet TH, Nanchen D et al. Impact of carotid plaque screening on smoking cessation and other cardiovascular risk factors: a randomized controlled trial. Arch Intern Med 2012; 172(4): 344–352. Dostupné z DOI: <http://dx.doi.org/10.1001/archinternmed.2011.1326>.
Wyman RA, Gimelli G, McBride PE et al. Does detection of carotid plaque affect physician behavior or motivate patients? Am Heart J 2007; 154(6): 1072–1077. Dostupné z DOI: <http://dx.doi.org/10.1016/j.ahj.2007.06.046>.
Korcarz CE, DeCara JM, Hirsch AT et al. Ultrasound detection of increased carotid intima-media thickness and carotid plaque in an office practice setting: does it affect physician behavior or patient motivation? J Am Soc Echocardiogr 2008; 21(10): 1156–1162. Dostupné z DOI: <http://dx.doi.org/10.1016/j.echo.2008.05.001>.
Bovet P, Perret F, Cornuz J et al. Improved smoking cessation in smokers given ultrasound photographs of their own atherosclerotic plaques. Prev Med 2002; 34(2): 215–220. Dostupné z DOI: <http://dx.doi.org/10.1006/pmed.2001.0976>.
Johnson JE, Gulanick M, Penckofer S et al. Does knowledge of coronary artery calcium affect cardiovascular risk perception, likelihood of taking action, and health-promoting behavior change? J Cardiovasc Nurs 2015; 30(1): 15–25. Dostupné z DOI: <http://dx.doi.org/10.1097/JCN.0000000000000103>.
Kalia NK, Cespedes L, Youssef G et al. Motivational effects of coronary artery calcium scores on statin adherence and weight loss. Coron Artery Dis 2015; 26(3): 225–230. Dostupné z DOI: <http://dx.doi.org/10.1097/MCA.0000000000000207>.
Warren JR, Falster MO, Tran B et al. Association of Continuity of Primary Care and Statin Adherence. PLoS One. 2015;10(10):e0140008. Dostupné z DOI: <http://dx.doi.org/10.1371/journal.pone.0140008>.
Chapman RH, Benner JS, Petrilla AA et al. Predictors of adherence with antihypertensive and lipid-lowering therapy. Arch Intern Med 2005;165(10): 1147–1152. Dostupné z DOI: <http://dx.doi.org/10.1001/archinte.165.10.1147>.
Halava H, Korhonen MJ, Huupponen R et al. Lifestyle factors as predictors of nonadherence to statin therapy among patients with and without cardiovascular comorbidities. CMAJ 2014; 186(12): E449-E456. Dostupné z DOI: <http://dx.doi.org/10.1503/cmaj.131807>.
Epstein RS. Medication adherence: hope for improvement? Mayo Clin Proc 2011; 86(4): 268–270. Dostupné z DOI: <http://dx.doi.org/10.4065/mcp.2011.0123>.
Piťha J. Jak (s)tvořit spolupracujícího pacienta pro antihypertenzní a hypolipidemickou léčbu. [How to create cooperative patient for antihypertensive and hypolipidemic therapy]. Vnitr Lek 2017; 63(4): 272–276.
Kawalec P, Holko P, Gawin M et al. Effectiveness of fixed-dose combination therapy in hypertension: systematic review and meta-analysis. Arch Med Sci 2018; 14(5): 1125–1136. Dostupné z DOI: <http://dx.doi.org/10.5114/aoms.2018.77561>.
Bahiru E, de Cates AN, Farr MR et al. Fixed-dose combination therapy for the prevention of atherosclerotic cardiovascular diseases. Cochrane Database Syst Rev 2017; (3): CD009868. Dostupné z DOI: <http://dx.doi.org/10.1002/14651858.CD009868.pub3>.
Selak V, Webster R, Stepien S et al. Reaching cardiovascular prevention guideline targets with a polypill-based approach: a meta-analysis of randomised clinical trials. Heart 2018. pii: heartjnl-2018–313108. Dostupné z DOI: <http://dx.doi.org/10.1136/heartjnl-2018–313108>.
[ASCEND Study Collaborative Group]. Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus. N Engl J Med 2018. Dostupné z DOI: <http://dx.doi.org/10.1056/NEJMoa1804988>.