Treatment of arterial hypertension in the elderly
Authors:
L. Jelínek; J. Václavík
Authors place of work:
I. interní klinika – kardiologická FN Olomouc, Olomouc
Published in the journal:
Kardiol Rev Int Med 2018, 20(1): 17-21
Summary
Arterial hypertension is one of the most important cardiovascular risk factors. Results of the HYVET and recent SPRINT clinical trials brought plenty of evidence that the treatment of hypertension in older patients is beneficial. Also patients with isolated systolic hypertension benefit from treatment. Specific methods of blood pressure reduction are finding their way into guidelines and we incorporate them into our daily practice, taking into account the patient’s clinical status. One current trend in treating the elderly, as well as other hypertensive patients, is the use of fixed single-pill combinations.
Key words:
arterial hypertension – old age – heart failure – adherence to treatment – diuretic – ACE inhibitors – stroke
Zdroje
1. Lawes CM, Vander Hoorn S, Law MR et al. Blood pressure and the global burden of disease 2000. Part II: estimates of attributable burden. J Hypertens 2006; 24(3): 423– 430.
2. ALLHAT Officers and Coordinatorsforthe ALLHAT CollaborativeResearch Group. The Antihypertensive and Lipid-LoweringTreatment to Prevent Heart Attack Trial. Major outcomes in high-risk hypertensivepatientsrandomized to angiotensin-converting enzyme inhibitor orcalciumchannelblockervsdiuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA 2002; 288(23): 2981– 2997.
3. Law MR, Morris JK, Wald NJ. Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the kontext of expectations from prospective epidemiological studies. BMJ 2009; 338: b1665. doi: 10.1136/ bmj.b1665.
4. Zdravotnická ročenka ČR 2016. Dostupné na: http: / / www.uzis.cz/ system/ files/ zdrroccz2016.pdf.
5. Beckett NS, Peters R, Fletcher AE et al. HYVET Study Group. Treatment of hypertension in patients 80 years of age or older. N Engl J Med 2008; 358(18): 1887– 1898. doi: 10.1056/ NEJMoa0801369.
6. Skoog I. Antihypertensive treatment and dementia prevention. Lancet Neurol 2008; 7(8): 664– 665. doi: 10.1016/ S1474-4422(08)70144-3.
7. PROGRESS Collaborative Group. Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack. Lancet 2001; 358(9287): 1033– 1041.
8. Kostis JB. Treating hypertension in the very old. N Engl J Med 2008; 358(18): 1958– 1960. doi: 10.1056/ NEJMe0801709.
9. Benetos A, Labat C, Rossignol P et al. Treatment with multiple blood pressure medications, achieved blood pressure, and mortality in older nursing home residents: The PARTAGE Study. JAMA Intern Med 2015; 175(6): 989– 995. doi: 10.1001/ jamainternmed.2014.8012.
10. Mancia G et al. Arterial Hypertension (Management of): ESC Clinical Practice Guidelines 2013. Available at: https: / / www.escardio.org/ Guidelines/ Clinical-Practice-Guidelines/ Arterial-Hypertension-Management-of.
11. Williamson JD, Supiano MA, Applegate WB et al. SPRINT Research Group. Intensivevs standard blood pressure control and cardiovascular disease outcomes in adults aged ≥75 years: a randomized clinical trial. JAMA 2016; 315(24): 2673– 2682. doi: 10.1001/ jama.2016.7050.
12. A randomized trial of intensive versus standard blood-pressure control. N Engl J Med 2017; 377(25): 2506. doi: 10.1056/ NEJMx170008.
13. Franklin SS, Jacobs MJ, Wong ND et al. Predominance of isolated systolic hypertension among middle-aged and elderly US hypertensives: analysis based on National Health and Nutrition Examination Survey (NHANES) III. Hypertension 2001; 37(3): 869– 874.
14. Franklin SS, Larson MG, Khan SA et al. Does the relation of blood pressure to coronary heart disease risk chase with aging? The Framingham Heart Study. Circulation 2001; 103(9): 1245– 1249.
15. Kang YY, Wang JG. The J-curve phenomenon in hypertension. Pulse 2016; 4(1): 49– 60. doi: 10.1159/ 000446922.
16. Treatment of hypertension in older adults, particularly isolated systolic hypertension. Up To Date 2017. Available at: https:/ / www.uptodate.com/ contents/ treatment-of-hypertension-in-older-adults-particularly-isolated-systolic-hyper-tension.
17. Burt VL, Whelton P, Roccella EJ et al. Prevalence ofhypertension in the US adult population. Results from the Third National Health and Nutrition Examination Survey, 1988– 1991. Hypertension 1995; 25(3): 305– 313.
18. Turnbull F, Neal B, Ninomiya T et al. Blood Pressure Lowering Treatment Trialists' Collaboration. Effectsof differentr egimens to lower blood pressure on major cardiovascular events in older and younger adults: meta-analysis of randomised trials. BMJ 2008; 336(7653): 1121– 1123. doi: 10.1136/ bmj.39548.738368.BE.
19. Lindholm LH, Carlberg B, Samuelsson O. Should beta blockers remain first choice in the treatment of primary hypertension? A meta-analysis. Lancet 2005; 366(9496): 1545– 1553. doi: 10.1016/ S0140-6736(05)67573-3.
20. Jamerson K, Weber MA, Bakris GL et al. ACCOMPLISH Trial Investigators. Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients. N Engl J Med 2008; 359(23): 2417– 2428. doi: 10.1056/ NEJMoa0806182.
21. Gangavati A, Hajjar I, Quach L et al. Hypertension, orthostatic hypotension, and the risk offalls in a community-dwelling elderly population: the maintenance of balance, independent living, intellect, and zest in the elderly of Boston study. J Am Geriatr Soc 2011; 59(3): 383– 389. doi: 10.1111/ j.1532-5415.2011.03317.x.
22. Figueora JJ, Basford JR, Low PA. Preventing and treating orthostatic hypotension: As easy as A, B, C. Cleve Clin J Mede 2010; 77(5): 298– 306. doi: 10.3949/ ccjm.77a.09118.
23. Fedorowski A, Stavenow L, Hedblad B et al. Orthostatic hypotension predicts all-cause mortality and coronary events in middle-aged individuals (The Malmö Preventive Project). Eur Heart J 2010; 31(1): 85– 91. doi: 10.1093/ eurheartj/ ehp329.
Štítky
Paediatric cardiology Internal medicine Cardiac surgery CardiologyČlánok vyšiel v časopise
Cardiology Review
2018 Číslo 1
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