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Verification of the reference range of free triiodothyronine in serum on the analyzer Architect ci 16200


Authors: T. Vacková;  J. Franeková;  A. Jabor
Authors place of work: Praha ;  Oddělení klinické biochemie, Pracoviště laboratorních metod, Institut klinické a experimentální medicíny
Published in the journal: Klin. Biochem. Metab., 26, 2018, No. 4, p. 178-181

Summary

Objective:

Verification of the reference interval of anew method for the determination of free triiodothyronine in serum on the Abbott Architect 16200 analyzer.

Design:

Original Article.

Settings:

Institute for Clinical and Experimental Medicine, Vídeňská 1958/9, 140 21 Praha

Material and methods:

The reference interval was validated on atotal of 110 serum samples from healthy subjects, comprising 55 females and 55 males. All samples used were from the IKEM Biobanka. The FT3_6 microparticle chemiluminescent immunoassay Abbott kit was used for the assay.

Results:

All free serum triiodothyronine values measured by the new fT3_6 method were in the reference interval indicated by the manufacturer. The reference range determined by anon-parametric statistical method with the Box-Cox transformation on the IKEM Biobanka samples was 3.21 - 4.78 pmol/L.

Conclusion:

The fT3 reference range established by the Abbott’s new fT3_6 method can be used in clinical practice with the range specified by the manufacturer.

Keywords:

Architect 16200, fT3, reference interval (RI).


Zdroje

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Clinical biochemistry Nuclear medicine Nutritive therapist
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