Complicated Herpetic Necrotising Meningoencephalitis Requiring Neurosurgical Intervention – a Case Report

Česká verzia

Authors: P. Prášil
Authors place of work: Klinika infekčních nemocí LF UK a FN Hradec Králové
Published in the journal: Cesk Slov Neurol N 2010; 73/106(3): 308-311
Category: Case Report

Summary

Herpetic diseases of the central nervous system, in particular certain forms of necrotising meningoencephalitis, are always perceived as a serious conditions. What may render this infection lethal is bleeding into encephalitic parts within the brain. Close collaboration between infectologist, neurologist, neurosurgeon and the radiodiagnostic team is vital to diagnosis and therapy. This study addresses viral herpes simplex types 1 and type 2, their pathophysiology, diagnostics and treatment. It also outlines the casuistics of complicated herpetic necrotising meningoencephalitis requiring neurosurgical intervention.

Key words:
neuroinfections – herpes simplex type 1– herpes simplex type 2 – necrotizing encephalitis – intracranial hemorrhage

Zdroje

1. Havlík J et al. Infekce vyvolané virem Herpes simplex typu l a 2. In: Havlík J (ed). Infektologie: učebnice pro lékařské fakulty. 2nd ed. Praha: Avicenum 1990: 264– 269.

2. Whitley RJ, Lakeman F. Herpes simplex virus infection of the central nervous systém: therapeutic and diagnostic considerations. Clin Infect Dis 1995; 20: 414– 420.

3. Corey L, Whitley RJ, Stone EF, Mohan K. Diference between herpes simplex virus type 1 and 2 neonatal encephalitis in neurological outcome. Lancet 1988; 1(8575– 8576): 1– 4.

4. Zaia J. Viral infections with bone marrow transplantation. Hematol Oncol Clin North Amer 1990; 4(3): 603– 623.

5. Rathore MH, Mercurio K, Halstead D. Herpes simplex virus type 1 meningitis. Pediatr Infect Dis J 1996; 15: 824– 828.

6. Goldsmith SM, Whitley RJ. Herpes simplex encephalitis system. Philadelphia: BC Decker 1991: 283– 299.

7. Craig CP, Nahmias AJ. Different pattern of neurologic involement with herpes simplexvirus types1 and 2: isolation of herpes simplex virus type 2 from the buffy coat of two adults with meningitis. J Infect Dis 1973; 127(4): 365– 372.

8. Davis LE, Johnson RT. An explanation for the localization of herpes simplex encephalitis? Ann Neurol 1979; 5(1): 2– 5.

9. Rozenberg F. Molecular pathogenesis of HSV latency and neurovirulence. Eurogin, European conference of STDs; Paris 1996.

10. Suchánková A, Piskunová N, Žampachová E, Dostál V, Plíšková L. Použití polymerázové řetězové reakce (PCR) v diagnostice neuroinfekcí vyvolaných herpes simplex virem 1 a 2. Klin Mikrobiol Inf Lék 2000; 6(2): 34– 38.

11. Cantin E, Chen J, Gaidulis L, Valo Z, Mc‑ Laughlin‑Taylor E. Detection of herpes simplex virus DNA sequences in human blood and bone marrow cells. J Med Virol 1994; 42(3): 279– 286.

12. Aurelius E, Johansson B, Sköldenberg B, Staland A, Forsgren M. Rapid diagnosis of herpes simplex encephalitis by nested polymerase chain reaction assay of cerebrospinal fluid. Lancet 1991; 337(8735): 189– 192.

13. Lobovská A et al. Herpes simplex virus 1, 2. In: Lobovská A (ed). Infekční nemoci. Praha: Univerzita Karlova 2001: 181– 182.

14. Dostál V et al. Herpetická encefalitida. In: Dostál V (ed). Infektologie. Praha: Karolinum 2004: 237– 238.

15. Grist NR, Ho‑ Yen DO, Walker E. Diseases of infection. An illustrated textbook. Oxford: Oxford University Press 1994: 170– 172.

16. Read SJ, Jeffery KJ, Bangham CR. Aseptic meningitis and encephalitis: the role of PCR in the diagnostic laboratory. J Clin Microbiol 1997; 35(3): 691– 696.

17. Mandell GL, Bennet JE, Dolin R. Herpes simplex virus. In: Mandell GL, Bennet JE, Dolin R (eds). Principles and Practice of Infectious Diseases. 6th ed. Philadelphia: Elsevier Churchill Livingstone 2005: 1773– 1774.

18. Sköldenberg B, Forsgren M, Alestig K, Bergström T,Burman L, Dahlqvist E et al. Acyclovir versus vidarabine in herpes simplex encephalitis: randomised multicentre study in consecutive Swedish patiens. Lancet 1994; 2(8405): 707– 711.