The structural basis for transport through the Fallopian tube

Česká verzia

Authors: M. Kajanová ^1,2; Ľudovít Danihel ³; Š. Polák ^2,4; M. Miko ²; L. Urban ^1,2; T. Bokor ³; I. Varga ^2,4
Authors place of work: Gynekologicko-pôrodnícke oddelenie, ForLife Všeobecná Nemocnica v Komárne, primár MUDr. F. Tóth, PhD. ¹; Ústav histológie a embryológie, Lekárska fakulta, Univerzita Komenského, Bratislava, prednosta doc. MUDr. Š. Polák, CSc. ²; Ústav patologickej anatómie, Lekárska fakulta, Univerzita Komenského, Bratislava, prednosta prof. MUDr. Ľ. Danihel, PhD. ³; Univerzitné pracovisko reprodukčnej medicíny, 1. gynekologicko-pôrodnícka klinika, Lekárska fakulta a Univerzitná Nemocnica, Univerzita Komenského, Bratislava, prednosta prof. MUDr. L. Borovský, CSc. ⁴
Published in the journal: Ceska Gynekol 2012; 77(6): 566-571

Summary

The Fallopian tube has until recently been a neglected structure, bypassed by in vitro fertilization and seen only as a tube that transports the oocyte or early embryo to the uterus. More recently, its role is even more undervalued after the introduction of techniques of assisted reproduction, in which the Fallopian tubes become like unnecessary. The Fallopian tube performs several important functions. It captures the oocyte after ovulation, maintains and controls the migration of spermatozoa to the site of fertilization. It provides the special microenvironment for fertilization; nourishes the early embryo while it is being carried to the uterus and amplifies signals from embryo to the mother. In our article we conducted a systematic review of relevant articles found in PubMed, Scopus and ISI Web of Knowledge, focused on the new insights into the functional morphology of Fallopian tube. We described the possible function of muscle layer motility, ciliary activity and tubal fluid movement on transport of gamets / embryo, as well as we mentioned the negative factors (such as smoking, chlamydial infection or endometriosis) affecting the transport through the Fallopian tube.

Key-words:
Fallopian tube, embryo transport, sperm migration, ciliary transport, tubal infertility.

Zdroje

1. Abu-Musa, A., Nassar, A., Usta, I. In vitro fertilization in two patients with Kartagener‘s syndrome and infertility. Gynecol Obstet Invest, 2008, 65, 1, p. 29–31.

2. Acién, P., Acién, MI. The history of female genital tract malformation classifications and proposal of an updated system. Hum Reprod Update, 2011, 17, 5, p. 693–705.

3. Adamkov, M., Varga I. Female reproductive system. In Adamkov, M. (Ed). Introduction to Functional Histology. Martin: P+M Turany, 2011, p. 333–362.

4. Ajonuma, LC., Ng, EH., Chan, HC. New insights into the mechanisms underlying hydrosalpinx fluid formation and its adverse effect on IVF outcome. Hum Reprod Update, 2002, 8, 3, p. 255–264.

5. Ankum, WM., Houtzager, HL., Bleker, OP. Reinier De Graaf (1641–1673) and the Fallopian tube. Hum Reprod Update, 1996, 2, 4, p. 365–369.

6. Baczynska, A., Funch, P., Fedder, J., et al. Morphology of human Fallopian tubes after infection with Mycoplasma genitalium and Mycoplasma hominis – in vitro organ culture study. Hum Reprod, 2007, 22, 4, p. 968–979.

7. Bhathiq, AOS., Ledger, WL. Historical backround and functioal anatomy. In Ledger, WL., Tan, SL., Bhathiq, AOS. The Fallopian tube in infertility and IVF practice. Cambridge: Cambridge University Press, 2010, p. 1–7.

8. Cebesoy, FB., Kutlar, I., Dikensoy, E., et al. Morgagni hydatids: a new factor in infertility? Arch Gynecol Obstet, 2010, 281, 6, p. 1015–1017.

9. Cigánková, V., Krajnicáková, H., Kokardová, M., Tomajková, E. Morphological changes in the ewe uterine tube (oviduct) epithelium during puerperium. Vet Med (Praha), 1996, 41, 11, p. 339–346.

10. Correr, S., Makabe, S., Heyn, R., et al. Microplicae-like structures of the fallopian tube in postmenopausal women as shown by electron microscopy. Histol Histopathol, 2006, 21, p. 219–226.

11. Cretoiu, SM., Cretoiu, D., Suciu, L., Popescu, LM. Interstitial Cajal-like cells of human Fallopian tube express estrogen and progesterone receptors. J Mol Histol, 2009, 40, 5–6, p. 387–394.

12. Croxatto, HB. Physiology of gamete and embryo transport through the fallopian tube. Reprod Biomed Online, 2002, 4, 2, p. 160–169.

13. Dahan, MH., Burney, R., Lathi, R. Congenital interruption of the ampullary portion of the Fallopian tube. Fertil Steril 2006, 85, 6, p. 1820–1821.

14. Djahanbakhch, O., Ezzati, M., Saridogan, E. Physiology and pathophysiology of tubal transport: ciliary beat and muscular contractility, relevance to tubal infertility, recent research, and future directions. In Ledger, WL., Tan, SL., Bhathiq, AOS. The Fallopian tube in infertility and IVF practice. Cambridge: Cambridge University Press, 2010, p. 19–29.

15. Downing, SJ., Chambers, EL., Maguiness, SD., et al. Effect of inflammatory mediators on the electrophysiology of the human oviduct. Biol Reprod, 1999, 61, 3, p. 657–664.

16. Holomáňová, A., Brucknerová, I. Anatomické názvy I. Latinsko-anglicko-slovenský slovník. Bratislava: Vydavateľstvo Elán, 2001, 94 s.

17. Hunt, JL., Lynn, AAA. Histologic features of surgically removed Fallopian tubes. Arch Pathol Lab Med, 2002, 126, p. 951–955.

18. Hunter, RH. Sperm release from oviduct epithelial binding is controlled hormonally by peri-ovulatory graafian follicles. Mol Reprod Dev, 2008, 75, 1, p.167–174.

19. Hunter, RH., Cicinelli, E., Einer-Jensen, N. Peritoneal fluid as an unrecognised vector between female reproductive tissues. Acta Obstet Gynecol Scand, 2007, 86, 3, p. 260–265.

20. Chung, PH., Yeko, TR., Mayer, JC., et al. Gamete intrafallopian transfer. Does smoking play a role? J Reprod Med, 1997, 42, 2, p. 65–70.

21. Jay, V. The legacy of Reinier De Graaf. Arch Pathol Lab Med, 2000, 124, 8, p. 1115–1116.

22. Kachlík, D., Čech, P., Musil, V., Báča, V. České tělovědné názvosloví. Návrh české anatomické nomenklatury podle poslední revize mezinárodně platné latinské anatomické nomenklatury. Brno: Tribun EU s.r.o., 2010, 170 s.

23. Kölle, S., Dubielzig, S., Reese, S., et al. Ciliary transport, gamete interaction, and effects of the early embryo in the oviduct: ex vivo analyses using a new digital videomicroscopic system in the cow. Biol Reprod, 2009, 81, 2, p. 267–274.

24. Lardenoije, CM., Land, JA. Chlamydia antibody testing for tubal factor subfertility. Ned Tijdschr Geneeskd, 2007, 151, 36, p. 1981–1985.

25. Laterza, RM., De Gennaro, M., Tubaro, A., Koelbl, H. Female pelvic congenital malformations. Part I: embryology, anatomy and surgical treatment. Eur J Obstet Gynecol Reprod Biol, 2011, 159, 1, p. 26–34.

26. Leese, HJ. The formation and function of oviduct fluid. J Reprod Fert, 1988, 82, p. 843–856.

27. Leese, HJ., Tay, JI., Reischl, J., Downing, SJ. Formation of Fallopian tubal fluid: role of a neglected epithelium. Reproduction, 2001, 121, 3, p. 339–346.

28. Li, J., Chen, X., Zhou, J. Ultrastructural study on the epithelium of ligated fallopian tubes in women of reproductive age. Ann Anat, 1996, 178, 4, p. 317–320.

29. Lyons, RA., Djahanbakhch, O., Mahmood, T., et al. Fallopian tube ciliary beat frequency in relation to the stage of menstrual cycle and anatomical site. Hum Reprod, 2002a, 17, 3, p. 584–588.

30. Lyons, RA., Djahanbakhch, O., Saridogan, E., et al. Peritoneal fluid, endometriosis, and ciliary beat frequency in the human Fallopian tube. Lancet, 2002b, 360, 9341, p. 1221–1222.

31. Lyons, RA., Saridogan, E., Djahanbakhch, O. The effect of ovarian follicular fluid and peritoneal fluid on Fallopian tube ciliary beat frequency. Hum Reprod, 2006, 21, 1, p. 52–56.

32. Menezo, Y., Guerin, P. The mammalian oviduct: biochemistry and physiology. Eur J Obstet Gynecol Reprod Biol, 1997, 73, p. 99–104.

33. Narayanan, R., Rajeev, MA. Duplication of the Fallopian tube.J Hum Reprod Sci, 2008, 1, 1, p. 35–36.

34. Paltieli, Y., Eibschitz, I., Ziskind, G., et al. High progesterone levels and ciliary dysfunction – a possible cause of ectopic pregnancy. J Assist Reprod Genet, 2000, 17, 2, p. 103–106.

35. Pabuccu, E., Kahraman, K., Taskın, S., Atabekoglu, C. Unilateral absence of fallopian tube and ovary in an infertile patient. Fertil Steril, 2011, 96, 1, p. e55–e57.

36. Polák, Š., Varga, I., Urban, L., Tóth, F. Chlamýdiové infekcie a reprodukčná schopnosť – I. časť. Praktická Med., 2008, 4, s. 17–20.

37. Popescu, LM., Ciontea, SM., Cretoiu, D., et al. Novel type of interstitial cell (Cajal-like) in human Fallopian tube. J Cell Mol Med, 2005, 9, 2, p. 479–523.

38. Popescu, LM., Ciontea, SM., Cretoiu, D. Interstitial Cajal-like cells in human uterus and Fallopian tube. Ann N Y Acad Sci, 2007, 1101, p. 139–165.

39. Rasheed, SM., Abdelmonem, AM. Hydatid of Morgagni: a possible underestimated cause of unexplained infertility. Eur J Obstet Gynecol Reprod Biol, 201,; 158, 1, p. 62–66.

40. Rodriguez-Martinez, H. Role of the oviduct in sperm capacitation. Theriogenology, 2007, 68S, p. 138–146.

41. Samaha, M., Woodruff, JD. Paratubal cysts: frequency, histogenesis, and associated clinical features. Obstet Gynecol, 1985, 65, 5, p. 691–694.

42. Savelli, L., Ghi, T., De Iaco, P., et al. Paraovarian/paratubal cysts: comparison of transvaginal sonographic and pathological findings to establish diagnostic criteria. Ultrasound Obstet Gynecol, 2006, 28, 3, p. 330–304.

43. Shi, D., Komatsu, K., Uemura, T., Fujimori, T. Analysis of ciliary beat frequency and ovum transport ability in the mouse oviduct. Genes Cells, 2011, 16, 3, p. 282–290.

44. Shin, YJ., Kim, JY., Lee, HJ., et al. Paratubal serous borderline tumor. J Gynecol Oncol, 2011, 22, 4, p. 295–298.

45. Strandell, A., Lindhard, A. Why does hydrosalpinx reduce fertility? The importance of hydrosalpinx fluid. Hum Reprod, 2002, 17, 5, p. 1141–1145.

46. Suarez, SS., Pacey, AA. Sperm transport in the female reproductive tract. Hum Reprod Update, 2006, 12, 1, p. 23–37.

47. Talbot, P., Riveles, K. Smoking and reproduction: the oviduct as a target of cigarette smoke. Reprod Biol Endocrinol, 2005, 3, p. 52.

48. Terek, MC., Sahin, C., Yeniel, AO., et al. Paratubal borderline tumor diagnosed in the adolescent period: a case report and review of the literature. J Pediatr Adolesc Gynecol, 2011, 24, 5, p. e115–e116.

49. Yazawa, H., Yabe, M., Endo, S., Hayashi, S. A case of congenital unilateral partial absence of fallopian tube. Fukushima J Med Sci, 2010, 56, 1, p. 44–49.

50. Záková, J., Ventruba, P., Crha, I., et al. Nové metody zvyšující úspěšnost asistované reprodukce. Čes Gynek, 2012 77, 2, s. 139–142.

51. Zervomanolakis, I., Ott, HW., Hadziomerovic, D., et al. Physiology of upward transport in the human female genital tract. Ann N Y Acad Sci, 2007, 1101, p. 1–20.