How to assess high-sensitive troponin T in newborns?
Authors:
P. Jehlička 1; M. Matas 2; D. Rajdl 3; M. Huml 1; A. Mocková 2; J. Dort 2; P. Brož 3; J. Sýkora 1
Authors place of work:
Dětská klinika, Fakultní nemocnice v Plzni, Univerzita Karlova v Praze, Lékařská fakulta v Plzni
přednosta prof. MUDr. J. Sýkora, Ph. D.
1; Neonatologické oddělení, Fakultní nemocnice v Plzni, Univerzita Karlova v Praze, Lékařská fakulta v Plzni
primář doc. MUDr. J. Dort, Ph. D.
2; Ústav klinické hematologie a biochemie, Fakultní nemocnice v Plzni, Univerzita Karlova v Praze, Lékařská fakulta v Plzni
přednosta prof. MUDr. J. Racek, DrSc.
3
Published in the journal:
Čes-slov Pediat 2016; 71 (4): 212-215.
Category:
Original Papers
Summary
In the prospective study cord blood samples were tested for high-sensitivity troponin T reference concentration in 454 healthy full termed newborns. The hscTnT levels in healthy newborns were significantly higher than levels in adult population (median [IQR] 38.2 [31.3–48.0] ng/l, reference interval: 20.1–83.0 ng/l). We found statistically higher hscTnT in boys when compared to girls (p=0.05). Concentrations of hscTnT were lower in newborns who underwent cesarean section than delivered vaginally (p=0.008). Furthermore, hscTnT was statistically significantly decreased in hemolytic blood samples (hemolysis level >2 g/l, p<0.05). Identified reference values of hscTnT based on this study may contribute to more precise assessment of newborns with suspicion of a myocardial disorder.
Key words:
high-sensitivity troponin T, newborns, myocardial disorder, hemolysis
Zdroje
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Štítky
Neonatology Paediatrics General practitioner for children and adolescentsČlánok vyšiel v časopise
Czech-Slovak Pediatrics
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