Advanced methods of external-beam radiation therapy in the treatment of prostate cancer
Authors:
Karel Odrážka- 1 3; Martin Doležel 1,3; Jaroslav Vaňásek 1
Authors place of work:
Oddělení radiační onkologie, Multiscan
s. r. o., Pardubická krajská nemocnice a. s.
Pardubice
1; 1. a 3. lékařská fakulta, Univerzita Karlova
v Praze
2; Katedra radiační onkologie IPVZ, Praha
3
Published in the journal:
Ces Urol 2010; 14(2): 81-91
Category:
Review article
Summary
In the last 20 years, external-beam radiation therapy of prostate cancer made a remarkable progress – entirely new treatment methods emerged and treatment results improved. Treatment planning using computed tomography and calculation of the spatial dose distribution launched the development of conformal techniques of radiation therapy (three-dimensional conformal radiation therapy 3D-CRT,intensity-modulated radiation therapy IMRT). Subsequent progress in imaging technologies and a focus on accurate setup of the radiation beam have opened a period of image-guided radiation therapy (IGRT) that moved conformal methods on higher level of quality and safety. Advanced forms of radiation therapy are associated with better dose distribution in comparison with conventional techniques, resulting in substantial sparing of healthy tissues. Radiation oncology took the advantage of conformal methods in full, aiming at the dose escalation in the prostate area. Randomized studies came to conclusive evidence regarding higher probability of cancer control with supraconventional doses of radiation.
Key words:
prostate cancer, external-beam radiation therapy, conformal techniques, image guidance.
Zdroje
1. Ray GR, Cassady JR, Bagshaw MA. Definitive radiation therapy of carcinoma of the prostate. A report on 15 years experience. Radiology 1973; 106: 407–418.
2. Hanks GE, Martz KL, Diamond JJ. The effect of dose on local control of prostate cancer. Int J Radiat Oncol Biol Phys 1988; 15: 1299–1305.
3. Sandler HM. 3-D conformal radiotherapy for prostate cancer. The University of Michigan Experience. In: Meyer JL, Purdy JA. (eds.) 3-D conformal radiotherapy. A new era in the irradiation of cancer. Basel: S. Karger 1996; 238–243.
4. Brahme A. Optimization of stationary and moving beam radiation therapy techniques. Radiother Oncol 1988; 12: 129–140.
5. Ling CC, Burman C, Chui CS, et al. Conformal radiation treatment of prostate cancer using inversely-planned intensity-modulated photon beams produced with dynamic multileaf collimation. Int J Radiat Oncol Biol Phys 1996; 35: 721–730.
6. Verhey LJ, Goitein M, McNulty P, Munzenrider JE, Suit HD. Precise positioning of patients for radiation therapy. Int J Radiat Oncol Biol Phys 1982; 8: 289–294.
7. De Neve W, Van den Heuvel F, De Beukeleer M, et al. Routine clinical on-line portal imaging followed by immediate field adjustment using a tele-controlled patient couch. Radiother Oncol 1992; 24: 45–54.
8. Michalski JM, Bae K, Roach M et al. Long-term toxicity following 3D conformal radiation therapy for prostate cancer from the RTOG 9406 phase I/II dose escalation study. Int J Radiat Oncol Biol Phys 2010; 76: 14–22.
9. Zelefski MJ, Levin EJ, Hunt M, et al. Incidence of late rectal and urinary toxicities after three-dimensional conformal radiotherapy and intensity-modulated radiotherapy for localized prostate cancer. Int J Radiat Oncol Biol Phys 2008; 70: 1124–1129.
10. Dearnaley DP, Sydes MR, Graham JD, et al. Escalated-dose versus standard-dose conformal radiotherapy in prostate cancer: first results from the MRC RT01 randomised controlled trial. Lancet Oncol 2007; 8: 475–487.
11. Al-Mamgani A, van Putten WL, Heemsbergen WD, et al. Update of Dutch multicenter dose-escalation trial of radiotherapy for localized prostate cancer. Int J Radiat Oncol Biol Phys 2008; 72: 980–988.
12. Kuban DA, Tucker SL, Dong L, et al. Long-term results of the M. D. Anderson randomized dose-escalation trial for prostate cancer. Int J Radiat Oncol Biol Phys 2008; 70: 67–74.
13. Zietman AL, DeSilvio ML, Slater JD, et al. Comparison of conventional-dose vs high-dose conformal radiation therapy in clinically localized adenocarcinoma of the prostate: a randomized controlled trial. JAMA 2005; 294: 1233–1239.
14. Shipley WU, Verhey LJ, Munzenrider JE, et al. Advanced prostate cancer: the results of a randomized comparative trial of high dose irradiation boosting with conformal protons compared with conventional dose irradiation using photons alone. Int J Radiat Oncol Biol Phys 1995; 32: 3–12.
15. Zelefski MJ, Yamada Y, Fuks Z, et al. Long-term results of conformal radiotherapy for prostate cancer: impact of dose escalation on biochemical tumor control and distant metastases-free survival outcomes. Int J Radiat Oncol Biol Phys 2008; 71: 1028–1033.
16. de la Rosette JJ, Mouraviev V, Polascik TJ. Focal targeted therapy will be a future treatment modality for early stage prostate cancer. Eur Urol Suppl 2009; 8: 424–432.
17. Mackie TR, Holmes T, Swerdloff S, et al. Tomotherapy: a new concept for the delivery of dynamic conformal radiotherapy. Med Phys 1993; 20: 1709–1719.
18. Weber DC, Wang H, Cozzi L, et al. RapidArc, intensity modulated photon and proton techniques for recurrent prostate cancer in previously irradiated patients: a treatment planning comparison study. Radiat Oncol 2009; 4: 34.
19. Yan D, Wong J, Vicini F, et al. Adaptive modification of treatment planning to minimize the deleterious effects of treatment setup errors. Int J Radiat Oncol Biol Phys 1997; 38: 197–206.
20. Fonteyne V, Villeirs G, Speleers B, et al. Intensity-modulated radiotherapy as primary therapy for prostate cancer: report on acute toxicity after dose escalation with simultaneous integrated boost to intraprostatic lesion. Int J Radiat Oncol Biol Phys 2008; 72: 799–807.
Štítky
Paediatric urologist Nephrology UrologyČlánok vyšiel v časopise
Czech Urology
2010 Číslo 2
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