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Successful endoscopic treatment of macroscopically advanced esophageal adenocarcinoma in a high-risk patient


Authors: Z. Vacková 1;  M. Stefanová 2;  I. Tučková 3;  A. Pazdro 5;  M. Smejkal 5;  M. Zemanová 4;  J. Špičák 1;  J. Martínek 1
Authors place of work: Klinika hepatogastroenterologie, IKEM, Praha 1;  Interní oddělení, Nemocnice Na Františku, Praha 2;  Patologické oddělení, ÚVN, Praha 3;  Onkologická klinika 1. LF UK a VFN, Praha 4;  III. chirurgická klinika 1. LF UK a FN v Motole, Praha 5
Published in the journal: Gastroent Hepatol 2013; 67(4): 271-274
Category: Clinical and Experimental Gastroenterology: Case Report

Summary

Combination of endoscopic mucosal resection (or submucosal dissection) with radiofrequency ablation is a method of choice for treatment of early esophageal neoplasia. Endoscopic therapy should be preferred for management of patients with intramucosal neoplasia. However, endoscopic treatment should also be considered in patients with more advanced le­sions (e.g. superficial submucosal cancer), particularly in those where surgery is an unacceptable risk or contraindicated due to severe comorbidities. We present a case of a successful endoscopic treatment of macroscopically, as well as histologically, advanced esophageal adenocarcinoma in a patient with liver cirrhosis Child-Pugh B. Endoscopic therapy consisted of two sessions of endoscopic mucosal resection and two sessions of radiofrequency ablation.

Key words:
Barrett's esophagus – endoscopic mucosal resection – radiofrequency ablation – esophageal adenocarcinoma

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE „uniform requirements“ for biomedical papers.

Submitted:
23. 7. 2013

Accepted:
5. 8. 2013


Zdroje

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9. Williams VA, Watson TJ, Herbella FA et al. Esophagectomy for high grade dysplasia is safe, curative, and results in good alimentary outcome. J Gastrointest Surg 2007; 11(12): 1589–1597.

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Štítky
Paediatric gastroenterology Gastroenterology and hepatology Surgery

Článok vyšiel v časopise

Gastroenterology and Hepatology

Číslo 4

2013 Číslo 4
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