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Granulomatous hepatitis as a rare therapeutic complication


Authors: K. Dvořák 1;  V. Šmíd 1;  R. Jakša 2
Authors place of work: IV. interní klinika – klinika gastroenterologie a hepatologie 1. LF UK a VFN v Praze 1;  Ústav patologie, 1. LF UK a VFN v Praze 2
Published in the journal: Gastroent Hepatol 2016; 70(2): 141-144
Category: Hepatology: Case Report
doi: https://doi.org/10.14735/amgh2016141

Summary

Intravesical BCG application is an established and relatively simple treatment for superficial carcinomas of the urinary bladder. It is usually well tolerated and has only mild side effects. We report a case of a 76-year-old immunocompetent man in whom this treatment led to a rare complication characterized by granulomatous hepatitis and pneumonitis. Elastography of the liver was used during diagnosis.

Key words:
granulomatous hepatitis – elastography – BCG – urinary bladder cancer

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE „uniform requirements“ for biomedical papers.

Submitted:
9. 3. 2016

Accepted:
7. 4. 2016


Zdroje

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3. Lamm DL, van der Meijden PM, Morales A et al. Incidence and treatment of complications of bacillus Calmette-Guerin intravesical therapy in superficial bladder cancer. J Urol 1992; 147(3): 596–600.

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8. Elkabani M, Greene JN, Vincent AL et al. Disseminated Mycobacterium bovis after intravesicular bacillus Calmette-Guerin treatments for bladder cancer. Cancer Control 2000; 7(5): 476–481.

9. Delimpoura V, Samitas K, Vamvakaris I et al. Concurrent granulomatous hepatitis, pneumonitis and sepsis as a complication of intravesical BCG immunotherapy. BMJ Case Rep 2013; 2013: pii: bcr2013200624. doi: 10.1136/bcr-2013-200624.

10. Gonzalez OY, Musher DM, Brar I et al. Spectrum of bacille Calmette-Guerin (BCG) infection after intravesical BCG immunotherapy. Clin Infect Dis 2003; 36(2): 140–148.

Štítky
Paediatric gastroenterology Gastroenterology and hepatology Surgery

Článok vyšiel v časopise

Gastroenterology and Hepatology

Číslo 2

2016 Číslo 2
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