Clinical practice guidelines for chronic hepatitis C virus infection

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6. Zeuzem S, Foster GR, Wang S et al. Glecaprevir-pibrentasvir for 8 or 12 weeks in HCV genotype 1 or 3 infection. N Engl J Med 2018; 378 (4): 354–369. doi: 10.1056/NEJMoa1702417.

7. Forns X, Lee SS, Valdes J et al. Glecaprevir plus pibrentasvir for chronic hepatitis C virus genotype 1, 2, 4, 5, or 6 infection in adults with compensated cirrhosis (EXPEDITION-1): a single-arm, open-label, multicentre phase 3 trial. Lancet Infect Dis 2017; 17 (10): 1062–1068. doi: 10.1016/S1473-3099 (17) 30496-6.

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10. Kowdley KV, Gordon SC, Reddy KR et al. Ledipasvir and sofosbuvir for 8 or 12 weeks for chronic HCV without cirrhosis. N Engl J Med 2014; 370 (20): 1879–1888. doi: 10.1056/NEJMoa1402355.

11. Naggie S, Cooper C, Saag M et al. Ledipasvir and sofosbuvir for HCV in patients coinfected with HIV-1. N Engl J Med 2015; 373 (8): 705–713. doi: 10.1056/NEJMoa1501315.

12. Reddy KR, Bourlière M, Sulkowski M et al. Ledipasvir and sofosbuvir in patients with genotype 1 hepatitis C virus infection and compensated cirrhosis: an integrated safety and efficacy analysis. Hepatology 2015; 62 (1): 79–86. doi: 10.1002/hep.27826.

13. Wilson E, Kattakuzhy S, Kwo P et al. Real-world effectiveness of 8 vs 12 weeks of ledipasvir/sofosbuvir (LDV/SOF) in Blacks with HCV: a comparative analysis of clinical trials with real-world cohorts. Hepatology 2017; 66: 608A. [online]. Available from: http: //www.natap.org/2017/AASLD/AASLD_133.htm.

14. Kowdley KV, Sundaram V, Jeon CY et al. Eight weeks of ledipasvir/sofosbuvir is effective for selected patients with genotype 1 hepatitis C virus infection. Hepatology 2017; 65 (4): 1094–1103. doi: 10.1002/hep.29005.

15. Buggisch P, Vermehren J, Mauss S et al. Real-world effectiveness of 8-week treatment with ledipasvir/sofosbuvir in chronic hepatitis C. J Hepatol 2018; 68 (4): 663–671. doi: 10.1016/j.jhep.2017.11.009.

16. Zeuzem S, Ghalib R, Reddy KR et al. Grazoprevir-elbasvir combination therapy for treatment-naive cirrhotic and noncirrhotic patients with chronic hepatitis C virus genotype 1, 4, or 6 infection: a randomized trial. Ann Intern Med 2015; 163 (1): 1–13. doi: 10.7326/M15-0785.

17. Rockstroh JK, Nelson M, Katlama C et al. Efficacy and safety of grazoprevir (MK-5172) and elbasvir (MK-8742) in patients with hepatitis C virus and HIV co-infection (C-EDGE COINFECTION): a non-randomised, open-label trial. Lancet HIV 2015; 2 (8): e319–e327. doi: 10.1016/S2352-3018 (15) 00114-9.

18. Kwo P, Gane EJ, Peng CY et al. Effectiveness of elbasvir and grazoprevir combination, with or without ribavirin, for treatment-experienced patients with chronic hepatitis C infection. Gastroenterology 2017; 152 (1): 164–175, e164. doi: 10.1053/j.gastro.2016.09.045.

19. Wei LJ, Zhdanov K, Burnevich E et al. Efficacy and safety of elbasvir/grazoprevir in treatment-naive patients with chronic HCV GT1, GT4 and GT6 infection (C-CORAL): a Phase III randomized multinational clinical trial. J Hepatol 2017; 66 (1): S529. doi: 10.1016/S0168-8278 (17) 31460-5.

20. Zeuzem S, Serfaty L, Vierling J et al. The safety and efficacy of elbasvir and grazoprevir in participants with hepatitis C virus genotype 1b infection. J Gastroenterol 2018; 53 (5): 679–688. doi: 10.1007/s00535-018-1429-3.

21. Abergel A, Hezode C, Asselah T et al. High efficacy and safety of grazoprevir and elbasvir for 8 weeks in treatment-naive, non-severe fibrosis HCV GT1b-infected patients: interim results of the STREAGER study. J Hepatol 2018; 68 (Suppl 1): S110. doi: 10.1016/S0168-8278 (18) 30437-9.

22. Ferenci P, Bernstein D, Lalezari J et al. ABT-450/r-ombitasvir and dasabuvir with or without ribavirin for HCV. N Engl J Med 2014; 370: 1983–1992. doi: 10.1056/NEJMoa1402338.

23. Dore GJ, Conway B, Luo Y et al. Efficacy and safety of ombitasvir/paritaprevir/r and dasabuvir compared to IFN-containing regimens in genotype 1 HCV patients: the MALACHITE-I/II trials. J Hepatol 2016; 64 (1): 19–28. doi: 10.1016/j.jhep.2015.08.015.

24. Wyles D, Saag M, Viani RM et al. TURQUOISE-I Part 1b: ombitasvir/paritaprevir/ritonavir and dasabuvir with ribavirin for hepatitis C virus infection in HIV-1 coinfected patients on darunavir. J Infect Dis 2017; 215 (4): 599–605. doi: 10.1093/infdis/jiw597.

25. Welzel TM, Asselah T, Dumas EO et al. Ombitasvir, paritaprevir, and ritonavir plus dasabuvir for 8 weeks in previously untreated patients with hepatitis C virus genotype 1b infection without cirrhosis (GARNET): a single-arm, open-label, Phase 3b trial. Lancet Gastroenterol Hepatol 2017; 2 (7): 494–500. doi: 10.1016/S2468-1253 (17) 30071-7.

26. Agarwal K, Gaeta BG, Lee SS et al. Long-term clinical outcomes in HCV genotype 1-infected patients receiving ombitasvir/paritaprevir/ritonavir and dasabuvir ± ribavirin: first interim safety and efficacy results from TOPAZ-I. Hepatology 2016; 64: 427. [online]. Dostupné z: http: //www.natap.org/2016/AASLD/AASLD_54.htm.

27. Welzel TM, Isakov V, Trinh R et al. Efficacy and safety of ombitasvir, paritaprevir/ritonavir and dasabuvir without ribavirin in patients with HCV genotype 1b with or without compensated cirrhosis: pooled analysis across 5 clinical trials. J Hepatol 2016; 64 (2): S824. doi: https: //doi.org/10.1016/S0168-8278 (16) 01613-5.

28. Foster GR, Afdhal N, Roberts SK et al. Sofosbuvir and velpatasvir for HCV genotype 2 and 3 infection. N Engl J Med 2015; 373 (27): 2608–2617. doi: 10.1056/NEJMoa1512612.

29. Lawitz E, Mangia A, Wyles D et al. Sofosbuvir for previously untreated chronic hepatitis C infection. N Engl J Med 2013; 368 (20): 1878–1887. doi: 10.1056/NEJMoa1214853.

30. Snopková S, Rozsypal H, Aster V et al. Doporučený postup péče o dospělé infikované HIV a postexpoziční profylaxe infekce HIV. [online]. Dostupné z: https: //www.infekce.cz/ DoporART16.htm.