An unusual case of systemic AA amyloidosis
Authors:
Zhychko K. 1; Douda L. 1; Soukup T. 1; Podhola M. 2; Bělobrádková M. 1; Bureš J. 1
Authors place of work:
II. interní gastroenterologická klinika LF UK a FN Hradec Králové
1; Fingerlandův ústav patologie LF UK a FN Hradec Králové
2
Published in the journal:
Gastroent Hepatol 2021; 75(4): 331-334
Category:
doi:
https://doi.org/10.48095/ccgh2021331
Summary
An unusual case of AA amyloidosis is presented. Pharmacotherapy of rheumatoid arthritis induced its 5-year clinical remission, yet despite this, the patient developed AA amyloidosis. Amyloidosis involved the stomach, duodenum and kidneys. AA amyloidosis did not impair the renal functions significantly. This case emphasized the importance of non-targeted biopsies of macroscopically normal mucosa of the stomach and duodenum that made it possible to diagnose amyloidosis. The patient remained without any gastrointestinal symptoms even during the subsequent follow-up.
Keywords:
AA amyloidosis – gastroscopy – non-targeted biopsies
Zdroje
1. Hokama A, Kishimoto K, Nakamoto M et al. Endoskopic and histopathological features of gastrointestinal amyloidosis. World J Gastrointest Endosc 2011; 3 (8): 157–161. doi: 10.4253/wjge.v3.i8.157.
2. Sipe JD, Cohen AS. Review: history of the amyloid fibril. J Struct Biol 2000; 130 (2–3): 88–98. doi: 10.1006/jsbi.2000.4221.
3. Zámečník J et al. Patologie. Praha: LD Prager Publishing 2019: 69–74.
4. Sipe JD, Benson MD, Buxbaum JN et al. Amyloid fibril protein nomenclature: 2010 recommendations from the nomenclature committee of the Internation Society of Amyloidosis. Amyloid 2010; 17 (3–4): 101–104. doi: 10.3109/13506129.2010.526812.
5. Ryšavá R. Systémové amyloidózy a jejich léčba. Praha: Maxdorf Jessenius 2013.
6. Ryšavá R. Postižení gastrointestinálního traktu amyloidózou – kdy na ni myslet a jak diagnostikovat. Gastroent Hepatol 2019; 73 (2): 154–162. doi: 10.14735/amgh2019154.
7. Zahradová L. Systémová amyloidóza. Onkológia (Bratisl) 2016; 11 (6): 361–364.
8. Gorevic P, Lachmann H, Romain P. Causes and diagnosis of AA amyloidosis and relation to rheumatic diseases. 2020 [online]. Available from: https: //www.uptodate.com/contents/causes-and-diagnosis-of-aa-amyloidosis-and-relation-to-rheumatic-diseases.
9. Camilleri M, Friedman SL, Grover S. Gastrointestinal amyloidosis: clinical manifestations, diagnosis, and management. 2021 [online]. Available from: https: //www.uptodate.com/contents/gastrointestinal-amyloidosis-clinical-manifestations-diagnosis-and-management.
10. Bureš J, Rejchrt S et al. Vyšetření tenkého střeva a enteroskopický atlas. Praha: Grada Publishing 2001.
11. Kohoutová D, Špaček J, Papík Z et al. Dysphagia, sicca syndrome, chronic non-infectious diarrhoea – dominant symptoms of systemic AL amyloidosis. A case report. Folia Gastroenterol Hepatol 2006; 4 (2): 72–78.
12. Tošovský M, Soukup T, Bradna P et al. Myopatie a smíšená hyperlipoproteinemie jako první pro-jev systémové AL-amyloidózy. Vnitř Lék 2008; 54 (10): 1014–1019.
13. Živný P. Amyloidóza. In: Bureš J, Horáček J, Malý J et al. Vnitřní lékařství. Praha: Galén 2014.
14. Komárková O, Fixa B, Nožička Z. Nodulární lymfatická hyperplazie tenkého střeva, případ s hypogamaglobulinemií a amyloidozou. Čs Gastroent Výž 1983; 37 (2): 103–108.
15. Nienhuis HL, Bijzet J, Hazenberg BP. The prevalence and management of systemic amyloidosis in western countries. Kidney Dis (Basel) 2016; 2 (1): 10–19. doi: 10.1159/000444 206.
16. Yamada T, Okuda Y. AA amyloid quantification in biopsy samples from the stomach. Ann Clin Lab Sci 2012; 42 (1): 3–6.
17. Yilmaz M, Unsal A, Sokmen M et al. Duodenal biopsy for diagnosis of renal involment in amyloidosis. Clin Nephrol 2012; 77 (2): 114–118. doi: 10.5414/CN107139.
18. Pika T, Heřmanová Z, Flodrová P. Laboratorní aspekty systémové AA amyloidózy. Klin Biochem Metab 2017; 25 (46): 56–58.
19. Leung N, Appel G. Renal amyloidosis. 2021 [online]. Available from: https: //www.uptodate.com/contents/renal-amyloidosis.
20. Gorevic P. Treatment of AA (secondary) amyloidosis. 2021 [online]. Available from: https: //www.uptodate.com/contents/treatment-of-aa-secondary-amyloidosis.
Štítky
Paediatric gastroenterology Gastroenterology and hepatology SurgeryČlánok vyšiel v časopise
Gastroenterology and Hepatology
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