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Trace elements and bone


Authors: I. Žofková 1;  P. Němčíková 2
Authors place of work: Endokrinologický ústav, Praha Ředitel: doc. MUDr. Vojtěch Hainer, CSc. 1;  3. lékařská fakulta UK, Praha Děkan: prof. MUDr. Michal Anděl, CSc. 2
Published in the journal: Prakt. Lék. 2010; 90(11): 646-648
Category: Various Specialization

Summary

The trace elements modulate many physiologic functions and have doubtless importance for the development of bone in foetal period, childhood and adolescence, as well as for integrity of the adult skeleton. Some of them have an osteoprotective effect (zinc), while others are toxic (cadmium, chromium, cobalt). Measurement of trace element concentrations in body fluids (blood and urine) or in tissues (hairs and bone) enables us to identify subjects at risk of osteoporotic fractures as a consequence of nutrition deficiency. The article reviews the current understanding of the role of trace elements in bone physiology.

Key words:
bone, copper, zinc, boron, fluor, magnesium, manganese, cobalt, chromium, cadmium.


Zdroje

1. Akesson, A., Bjellerup, P., Lundh, T. et al. Cadmium-induced effects on bone in a population-based study od women. Environ. Health Perspect. 2006, 114, p. 830-834.

2. Azpeitia-Valadez, Mde, Rodríguez-Frausto, M., Sánchez-Hernández, M.A. Prevalence of dental fluorosis in children between 6- 15 years old. Rev. Med. Inst. Mex. Seguro. Soc. 2008, 46, p. 67-72.

3. Atik, O.S., Uslu, M.M., Eksioglu, F., Satana, T. Etiology of senile osteoporosis. A hypothesis. Clin. Orthopaed. Related. Res. 2006, 443, p. 25-27.

4. Devirian, T.A., Volpe, S.L. The physiological effects of dietary boron. Critical Rev. Food. Sci. Nutr. 2003, 43, p. 219-231.

5. Kanazawa, I., Yamamoto, M., Yamaguchi, T.Z. et al. A case of magnesium deficiency associated with insufficient parathyroid hormone action and severe osteoporosis. Endocr. J. 2007, 54, p. 935-940.

6. Maverakis, E., Fung, M.A., Lunch, P.J. et al. Acrodermatitis enteropathica and an overview of zinc metabolism. J. Am. Acad. Dermatos. 2007, 56, p. 116-124.

7. Mutlu, M., Argun, M., Kilic, E. et al. Magnesium, zinc and copper status in osteoporotic, osteopenic and normal post-menopausal women. J. Int. Med. Res. 2007, 35, p. 692-695.

8. Němčíková, P., Spěváčková V., Čejchanová, M., Hill, M., Žofková, I. Vztah sérových hladin manganu a mědi k denzitě a kvalitě kosti u postmenopauzálních žen. Pilotní studie. Osteologický bulletin 2009, 14, s. 97-100.

9. Parelman, M., Stoecker, B., Baker, A., Madeiros, D. Iron restriction negatively affects bone in female rats and mineralization of hFOB osteoblast cells. Exp. Biol. Med. (Maywood) 2006, 231, p. 378-386.

10. Rico, H., Gómez-Raso, N., Sevilla, M. et al. Effects on bone loss of manganese alone or with copper supplement in ovariectomized rats. A morphometric and denzitometric study. Eur. J. Obstet. Gynecol. Reprod. Biol. 2000, 90, p. 97-101.

11. Žofková I., Němčíková P. Stopové prvky a jejich vztah ke kostnímu metabolismu. Diabetologie, metabolismus, endokrinologie, výživa 2008, 4, s. 172-176.

Štítky
General practitioner for children and adolescents General practitioner for adults
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