Acellular porcine dermis in local treatment of diabetic food syndrome

Česká verzia

Authors: M. Dubský ¹; A. Jirkovská ¹; R. Bém ¹; B. Sixta ²; V. Fejfarová ¹; L. Řezaninová ¹; E. Matoušková ³; J. Skibová ⁴
Authors place of work: Centrum diabetologie IKEM, Praha Přednostka: prof. MUDr. Terezie Pelikánová, DrSc. ¹; Klinika transplantační chirurgie IKEM, Praha Přednosta: prof. MUDr. Miloš Adamec, CSc. ²; Klinika popáleninové medicíny, 3. LF UK a FNKV Přednosta: doc. MUDr. Leo Klein, CSc. ³; Oddělení statistiky IKEM ⁴
Published in the journal: Prakt. Lék. 2010; 90(6): 342-348
Category: Of different specialties

Summary

Diabetic foot disease is one of the most common and most severe complications of diabetes. Aetiology of chronic ulcers is multifactorial and adequate therapy is often very difficult. Acellular porcine dermis could be used to treat chronic wounds with no signs of osteomyelitis and without critical ischaemia. The main advantages of acellular porcine dermis are its ability to be stored for long periods in dried form and its availability. In accordance with the results of our pilot study performed on 14 patients, the use of acellular porcine dermis in therapy of superficial non-infected ulcers was more efficient than with xenografts and is an appropriate alternative to modern bioengineered skin substitutes. We did not observe any serious adverse effects of this treatment.

Keywords:
diabetic foot, wound healing, skin substitutes, xenografts.

Zdroje

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