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Allergic bronchopulmonary aspergillosis


Authors: L. Heribanová
Authors place of work: Přednosta: prof. MUDr. Jiří Homolka, DrSc. ;  Primářka: doc. MUDr. Martina Vašáková, PhD. ;  Pneumologická klinika 1. LF UK a Thomayerovy nemocnice, Praha
Published in the journal: Prakt. Lék. 2014; 94(2): 59-63
Category: Reviews

Summary

Allergic bronchopulmonary aspergillosis (ABPA) is a Th2 hypersensitive response to A. fumigatus colonization of airways in predisposed persons, that predominantly affects asthmatic and cystic fibrosis patients. A number of genetic risk factors have been identified to play a role in the development of ABPA. The diagnostic assessment ABPA is based on the presence of a combination of clinical, laboratory and radiological findings, the early detection of the disease and the adequate treatment have a major effect on the prognosis of patients.

Keywords:
allergic bronchopulmonary aspergillosis – asthma bronchiale – A. fumigatus


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