Can serum level of vitamin D influence a lenght of senior´s hospitalization?
Authors:
H. Matějovská Kubešová; J. Matějovský; K. Bielaková
Published in the journal:
Geriatrie a Gerontologie 2016, 5, č. 4: 181-189
Category:
Original Article/Study
Summary
Introduction.
Low serum levels of vitamin D have been repeatedly found in most of the middle geographic area population since routine vitamin D examination were introduced. There is an increasing amount of information available regarding the role of vitamin D in many important functions of the human body including muscle mass and muscle strength – one of important parameters of independence.
The main aim of this work was to assess the relationship between vitamin D serum level and the independence level according to ADL test results and the cognitive performance according the MMSE results in seniors hospitalized because of acute health complications. Moreover, the relationship between vitamin D serum level and the course of acute health complications was studied.
Results.
We studied 151 hospitalized probands – 116 (77 %) women and 35 (23 %) men of average age 81,05 ± 7,44 years. The serum vitamin D level evaluation discovered 66,9 % of probands with unsatisfactory levels of below 37,5 nmol/l. Vitamin D serum level showed significant positive correlation with starting and final ADL test results (r = 0,29, p < 0,01) and MMSE r = 0,28, p < 0,01). Probands with higher starting vitamin D serum level achieved quicker recovery of ADL results.
Conclusions.
Two thirds of studied group of seniors did not achieve sufficient vitamin D serum level for adequate bone remodelling. Probands with higher vitamin D serum level showed higher level of independence according to ADL test results and better cognitive performance according to MMSE test results. Quicker independence restoration following acute health complication was found in patients with higher vitamin D serum level.
KEYWORDS:
vitamin D – independence – bone remodeling – duration of hospitalization – cognitive performance
Zdroje
1. Suominen MH, Jyvakorpi SK, Pitkala KH, et al. Nutritional guidelines for older people in Finland. J Nutr Health Aging 2014; 18(10): 861–867.
2. Šašinka M, Furková K. Vitamin D u starších ľudí. Geriatria 2012; 21–28.
3. Grant WB. Ecological studies of the UVB-vitamin D-cancer hypothesis. Anticancer Research 2012; 32(1): 223–236.
4. Granic A, Hill TR, Kirkwood TBL, et al. Serum 25-hydroxyvitamin D and cognitive decline in the very old: The Newcastle 85+ study. European Journal of Neurology 2015; 22(1): 106–107.
5. Hansdottir S, Monick M. Vitamin D effects on lung immunity and respiratory diseases. Vitamins and Hormones 2011; 86: 217–237.
6. Krajčík Š. Sarkopénia. Geriatria 2013; 1: 15–20.
7. Scott D, Blizzard L, Fell J, et al. A prospective study of the associations between 25-hydroxy-vitamin D, sarcopenia progression and physical activity in older adults. Clinical Endocrinology 2010; 73: 581–587.
8. Meehan M, Penckofer S. The role of vitamin D in the aging adults. Journal of Aging and Gerontology 2014; 2014: 2(12): 60–71.
9. Bischoff-Ferrari HA, Dawson-Hughes B, Staehelin HB, et al. Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials. British Medical Journal 2009; 339: b3692.
10. Annweiler C, Beauchet O. Questioning vitamin D status of elderly fallers and non-fallers: a metaanalysis to address a forgotten step. Journal of Internal Medicine 2015; 277(1): 16–44.
11. Slíva J. Vliv suplementace kalciem a vitaminem D na kostní denzitu, na riziko osteoporotických fraktur a na výskyt pádů u seniorů. Medicína po promoci 2016; 17(2): 151–152.
12. Cranney A, Horsley T, O´Donnel S, et al. Effectiveness and safety of vitamin D in relation to bone health. Evidence Report-Technology Assessment 2007; 158: 231–235.
13. Safer U, Safer VB, Demir SO, Yanikoglu I. Effects of Bisphosphonates and Calcium plus Vitamin-D Supplements on Cognitive Function in Postmenopausal Osteoporosis. Endocrine Metabolic & Immune Disorders – Drug Targets 2016; 3(16): 56–60.
14. Oudshoom C, Matrace Raso FU, van der Velde N, et al. Higher vitamin D serum levels are associated with better cognitive test performance in patients with Alzheimer´s disease. Dementia and Geriatric Cognitive Disorders 2008; 25(6): 539–543.
15. Evatt ML, Delong MR, Kazai N, et al. Prevalence of vitamin D insufficiency in patiens with Parkinson disease and Alzheimer diasease. Archives of Neurology 2008; 65(10): 1348–1352.
16. Schoor NM, Comijs HC, Llewellyn DJ, et al. Cross-sectional and longitudinal associations between serum 25-hydroxyvitamin D and cognitive functioning. International Psychogeriatrics 2016; 28(5): 759–768.
17. Gezen-Ak D, Durzun E, Ertan T, et al. Association between vitamin D receptor gene polymorphism and Alzheimer´s disease. Tohoku. The Journal of Experimental Medicine 2007; 3: 275–282.
18. Kalvach Z, Zadák Z, Jirák R, et al. Geriatrie a gerontologie. Praha: Grada 2004, s. 541.
19. Topinková E. Geriatrie pro praxi. Praha: Galén 2005; s. 270.
20. Suchý D, Hromádka M. Příspěvek k problematice geriatrické farmakoterapie. Praktické lékárenství 2011; 7(3): 111–114.
21. Vyskočil V. Vitamin D. Klinická farmakologie a farmacie 2011; 25: 72–75.
22. SPC Caltrate 600 mg/400 IU D3.
23. Ganji V, Zhang X, Tangpricha V. Serum 25-hydroxyvitamin D concentrations and prevalence estimates of hypovitaminosis D in the US population based on assay-adjusted data. Journal of Nutrition 2012; 143(3): 498–507.
24. Wright L, Vance L, Sudduth C, Epps JB. The impact of a home-delivered meal program on nutritional risk dietary intake, food security loneliness and social wellbeing. Journal of Nutrition in Gerontology and Geriatrics 2015; 34(2):18–27.
25. Skalska A, Galas A, Grodzicki T. 25-hydroxyvitamin D and physical and cognitive performance in older people with chronic conditions. Polskie Archiwum Medycyny Wewnetrzene 2012; 122(4): 162–169.
26. Salminen M, Saaristo P, Salonoja M, et al. Vitamin D status and physical function in older Finnish people: A one year follow-up study. Archives of Gerontology and Geriatrics 2015; 61(3): 419–424.
27. Gschwind YJ, Bischoff-Ferrari H A, Bridenbaugh SA, et al. Association between serum vitamin D status and functional mobility in memory clinic patients aged 65 years and older. Gerontology 2014; 60(2): 123–129.
28. Matejovsky J, Matejovska Kubesova H, Meluzinova H, et al. Seniors with mild cognitive impairment – What happened in seven years? – Poster 8th Congress of the International Assotiation of Gerontology and Geriatrics – European Region 2015, Dublin 23.–26. dubna 2015. Irish Ageing Studies Review 2015; 6(1): 339.
Štítky
Geriatrics General practitioner for adults Orthopaedic prostheticsČlánok vyšiel v časopise
Geriatrics and Gerontology
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