Antiaggregant therapy

Česká verzia

Authors: J. Malý; M. Pecka; P. Ďulíček; M. Blažek; L. Smolej
Authors place of work: II. interní klinika Lékařské fakulty UK a FN, Hradec Králové, přednosta prof. MUDr. Jaroslav Malý, CSc.
Published in the journal: Vnitř Lék 2005; 91(7 a 8): 826-832
Category: 128th Internal Medicine Day - 21rd Vanysek's Day Brno 2005

Summary

Antiaggregant treatment is suitable for all at risk patients with atherothrombosis and its cardiovascular complications. Antiaggregant treatment decreases severe vascular events in at risk patients, myocardial infarctions, non-fatal strokes, transient ischaemic attacks, unstable angina, obstructive peripheral vascular disease. It decreases a risk of embolism caused by atrial fibrillation and a risk of vascular occlusion in other patients at high risk. Antiaggregant treatment should be administered long-term. The basic antiaggregant drug is acetylsalicylic acid (ASA) which is commonly used in doses of 75–150 mg daily. Acetylsalicylic acid is an effective antiaggregant drug with clearly demonstrated beneficial effect on atherothrombotic complications in cardiovascular diseases. Other substances and drugs with antiaggregant effect including their modes of action and indications are reviewed.

Keywords:
cardiovascular diseases – antiaggregant therapy

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