Acute pancreatitis – Validation of Revised Atlanta Classification on 159 patients and prognostic factors

Česká verzia

Authors: Katarína Floreánová ¹; Petr Dítě ²; Bohuslav Kianička ³; Lenka Dovrtělová ⁴; Marie Přecechtělová ¹
Authors place of work: Interní gastroeneterologická klinika LF MU a FN Brno, pracoviště Bohunice, přednosta prof. MUDr. Aleš Hep, CSc. ¹; Akademické centrum gastroenterologie Interní kliniky LF OU a FN Ostrava, přednosta doc. MUDr. Arnošt Martínek, CSc. ²; Gastroenterologické oddělení II. interní kliniky LF MU a FN u sv. Anny Brno, přednosta prof. MUDr. Miroslav Souček, CSc. ³; Katedra podpory zdraví Fakulty sportovních studií MU Brno, vedoucí katedry Mgr. Lenka Dovrtělová, Ph. D. ⁴
Published in the journal: Vnitř Lék 2014; 60(7-8): 567-574
Category: Original Contributions

Summary

Introduction:
In the last few years the Atlanta classification of acute pancreatitis (AP) have been revised. However prognostic markers of AP are still being searched for. The aim of this study is to validate the 3 severity cathegories proposed by the revised Atlanta classification. We also tried to reevaluate the association between two laboratory markers (leucocyte count and RDW – red cell distribution width) on admission and prognosis of the patients with AP.

Methods:
159 patients were included into the study. The patients were classified according to revised Atlanta criteria and the subgroups evaluated according to mortality, lenght of hospital stay and need for interventions. Leucocyte count and RDW on admission was evaluated in the patients.

Results:
All the subgroups of patients were associated with significantly relevant differences in mortality, lenght of hospital stay and need for operations on pancreas. Leucocyte count and RDW were identified as significant predictors for severe AP and RDW was also identified as significant predictor for mortality in patients with AP.

Conclusion:
New categories of severity as defined by Revised Atlanta classification are describing well the mortality, lenght of hospital stay and need for interventions in the patients with AP. Leucocyte count and RDW on admission are needed to be confirmed as potential prognostic markers of severity and mortality in AP.

Key words:
acute pancreatitis – Atlanta classification – leucocyte count – mild form – moderately form – prognostic factors – RDW – severe form

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