The Use of Paracetamol in Children –Benefits and Risks

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Paracetamol u dětí – nejen lék, ale i jed

Paracetamol je známá analgetická a antipyretická látka. V pediatrii je paracetamol nejčastěji užívaným analgetikem a antipyretikem. Při předávkování ohrožuje vysokou morbiditou a mortalitou. Článek podává přehled o použití paracetamolu u dětí, rizicích jeho podávání a možnostech léčby při intoxikaci. Autoři upozorňují na opomíjenou toxicitu paracetamolu a jeho časté podávání dětem při neznalosti potenciálních život ohrožujících rizik. Jako příklad je uvedena kazuistika dvouletého dítěte s těžkou otravou paracetamolem.

Klíčová slova:
paracetamol, intoxikace paracetamolem, CVVH.

Authors: A. Olosová; I. Láryšová; T. Zaoral; A. Bakhtary
Authors‘ workplace: Oddělení pediatrické resuscitační a intenzivní péče FN, Ostrava
Published in: Čas. Lék. čes. 2007; 146: 401-405
Category: Case Report

Overview

Acetaminophen is the most widely used analgesic drug in pediatrics. It is also the most frequently ingested drug in overdoses. The incidence of paracetamol poisoning has increased and it is accompanied with high morbidity and mortality. The use, abuse and ways of reducing paracetamol toxicity are reviewed. A case report of lethal acetaminophen intoxication in 2-year-old child is described. Authors draw attention to the health care providers – they should consider acetaminophen toxicity in all cases when the child has signs of acute hepatic dysfunction.

Key words:
acetaminophen, toxicity acetaminophen, CVVH.

Labels

Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental Hygienist

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