Deep brain stimulation in movement disorders: a Prague-center experience
Authors:
Dušan Urgošík 1,2; Robert Jech 2; Evžen Růžička 2; Filip Růžička 1; Roman Liščák 1; Vilibald Vladyka 1
Authors place of work:
Oddělení stereotaktické a radiační neurochirurgie Nemocnice Na Homolce, Praha
1; Univerzita Karlova v Praze, 1. lékařská fakulta, Neurologická klinika a Centrum klinických neurověd VFN
2
Published in the journal:
Čas. Lék. čes. 2011; 150: 223-228
Category:
Review Article
Summary
Deep brain stimulation (DBS) in the basal ganglia plays an irreplaceable role in the treatment of Parkinson’s disease (PD), essential tremor (ET), and some types of dystonia. Electrodes are typically inserted into the subthalamic nucleus (STN), the internal globus pallidus (GPi) and the ventral intermediate nucleus of the thalamus (VIM). Stimulation of the STN is the main objective in PD, GPi in the treatment of dystonia and PD, and VIM stimulation is effective against tremor. In patients indicated for DBS treatment, stimulation eliminates or reduces rigidity (PD), hypokinesia (PD), tremor (ET, PD) and dyskinesias (dystonia, PD). At the Center for Movement Disorders in Prague, DBS has been performed in 127 patients: in 86 patients for PD, 19 patients for dystonia (11 primary generalized dystonia, 5 primary cervical dystonia, 1 segmental craniocervical dystonia), and in 22 patients for tremor (20 ET, 2 other types of tremor). Intraoperatively we have succeeded in eliminating rigidity in 95% of cases of PD, and tremor in 93% of cases of ET. The positive effect of stimulation on dystonia appeared in 95% with a latency of weeks. Transitory intraoperative morbidity occurred in 8%, intracranial hemorrhage in 1%, infectious complications in 6%, and problems with hardware in 7%.
Key words:
deep brain stimulation, stereotaxy, Parkinson’s disease, tremor, dystonia.
Zdroje
1. Benabid AL, Pollak P, Louveau A, Henry S, de Rougemont J. Combined (thalamotomy and stimulation: stereotactic surgery of the VIM thalamic nucleus for bilateral Parkinson disease. Appl Neurophysiol 1987; 50: 344–346.
2. Blond S, Siegfried J. Thalamic stimulation for the treatment of tremor and other movement disorders. Acta Neurochir (Wien) 1991; 52 (Suppl): 109–111.
3. Benabid AL, Pollak P, Gervason C, Hoffmann D, Gao DM, Hommel M, Perret JE, de Rougemont J. Long-term suppression of tremor by chronic stimulation of the ventral intermediate thalamic nucleus. Lancet 1991; 337(8738): 403–406.
4. Siegfried J. Therapeutic stereotactic procedures on the thalamus for motor movement disorders. Acta Neurochir (Wien) 1993; 124: 14–18.
5. Pollak P, Benabid AL, Gross C, Gao DM, Laurent A, Benazzouz A, Hoffmann D, Gentil M, Perret J. Effects of the stimulation of the subthalamic nucleus in Parkinson disease. Rev Neurol (Paris) 1993; 149: 175–176.
6. Siegfried J, Lippitz B. Bilateral chronic electrostimulation of ventroposterolateral pallidum: a new therapeutic approach for alleviating all parkinsonian symptoms. Neurosurgery 1994; 35: 1126–1129; discussion 1129–1130.
7. Benabid AL, Pollak P, Gross C, Hoffmann D, Benazzouz A, Gao DM, Laurent A, Gentil M, Perret J. Acute and long-term effects of subthalamic nucleus stimulation in Parkinson’s disease. Stereotact Funct Neurosurg 1994; 62: 76–84.
8. Jech R, Urgosik D, Tintera J, Nebuzelsky A, Krasensky J, Liscak R, Roth J, Ruzicka E. Functional magnetic resonance imaging during deep brain stimulation: a pilot study in four patients with Parkinson’s disease. Mov Disord 2001; 16: 1126–1132.
9. Walker HC, Watts RL, Schrandt CJ, Huang H, Guthrie SL, Guthrie BL, Montgomery EB Jr. Activation of Subthalamic Neurons by Contralateral Subthalamic Deep Brain Stimulation in Parkinson Disease. J Neurophysiol 2010; 105: 1112–1121.
10. Schaltenbrand G, Wahren W. Atlas for stereotaxy of the human brain. Stuttgart: Georg Thieme Publishers 1977.
11. Benazzouz A, Breit S, Koudsie A, Pollak P, Krack P, Benabid AL. Intraoperative microrecordings of the subthalamic nucleus in Parkinson’s disease. Mov Disord 2002; 17 (Suppl 3): S145–S149.
12. Růžička E, Urgošík D, Jech R, Serranová T, Volfová M, Roth J, Vymazal J, Mečíř P, Nováková L, Nováková O, Ulmanová O, Brožová H, Dušek P, Špačková N, Liščák R, Vladyka V. Hluboká mozková stimulace v léčbě Parkinsonovy nemoci a třesu: Pražská zkušenost 1998–2003. Cesk Slov Neurol N 2004; 67/100: 423–436.
13. Ruzicka E, Jech R, Zarubova K, Roth J, Urgosik D. VIM thalamic stimulation for tremor in a patient with IgM paraproteinaemic demyelinating neuropathy. Mov Disord 2003; 18: 1192–1195.
14. Fahn S, Tolosa E, Maria C. Clinical rating scale for tremor. In: Jankovic J, Tolosa E. Parkinson’s disease and movement disorders. Baltimore: Williams and Wilkins 1993; 271–280.
15. Vasques XA, Cif L, Biolsi B, Coubes P. Central procedures for primary dystonia. In: Lozano AM, Gildenberg PL, Tasker RR. Textbook of stereotactic and functional neurosurgery. Berlin-Heidelberg: Springer Verlag 2009; 1801–1834.
16. Coubes P, Cif L, El Fertit H, Hemm S, Vayssiere N, Serrat S, Picot MC, Tuffery S, Claustres M, Echenne B, Frerebeau P. Electrical stimulation of the globus pallidus internus in patients with primary generalized dystonia: long-term results. J Neurosurg 2004; 101: 189–194.
17. Volkmann J, Sturm V, Weiss P, Kappler J, Voges J, Koulousakis A, Lehrke R, Hefter H, Freund HJ. Bilateral high-frequency stimulation of the internal globus pallidus in advanced Parkinson’s disease. Ann Neurol 1998; 44: 953–961.
18. Kumar R, Dagher A, Hutchison WD, Lang AE, Lozano AM. Globus pallidus deep brain stimulation for generalized dystonia: clinical and PET investigation. Neurology 1999; 53: 871–874.
19. Castelnau P, Cif L, Valente EM, Vayssiere N, Hemm S, Gannau A, Digiorgio A, Coubes P. Pallidal stimulation improves pantothenate kinase-associated neurodegeneration. Ann Neurol 2005; 57: 738–741.
20. Kumar R, et al. Deep brain stimulation of the globus pallidus pars interna in advanced Parkinson’s disease. Neurology 2000; 55(Suppl 6): S34–S39.
21. Volkmann J, et al. Long-term results of bilateral pallidal stimulation in Parkinson’s disease. Ann Neurol 2004; 55: 871–875.
22. Rodrigues JP, et al. Globus pallidus stimulation improves both motor and nonmotor aspects of quality of life in advanced Parkinson’s disease. Mov Disord 2007; 22: 1866–1870.
23. Ghika J, et al. Efficiency and safety of bilateral contemporaneous pallidal stimulation (deep brain stimulation. in levodopa-responsive patients with Parkinson’s disease with severe motor fluctuations: a 2-year follow-up review. J Neurosurg 1998; 89: 713–718.
24. Krause M, et al. Deep brain stimulation for the treatment of Parkinson’s disease: subthalamic nucleus versus globus pallidus internus. J Neurol Neurosurg Psychiatry 2001; 70: 464–470.
25. Pahwa R, Lyons KE, Wilkinson SB, Simpson RK Jr, Ondo WG, Tarsy D, et al. Long-term evaluation of deep brain stimulation of the thalamus. J Neurosurg 2006; 104: 506 –512.
26. Benabid AL, Pollak P, Gao D, Hoffmann D, Limousin P, Gay E, et al. Chronic electrical stimulation of the ventralis intermedius nucleus of the thalamus as a treatment of movement disorders. J Neurosurg 1996; 84: 203–214.
27. Burke RE, Fahn S, Marsden CD, Bressman SB, Moskowitz C, Friedman J. Validity and reliability of a rating scale for the primary torsion dystonias. Neurology 1985; 35: 73–77.
28. Consky E, Basinki DJ, Ranawaya R, Lang AE. The Toronto Western Spasmodic Torticollis Ratin Scale (TWSTRS): assessment of validity and inter-rater reliability. Neurology 1990; 40(Suppl 1): 445.
29. Krauss JK, Loher TJ, Pohle T, Weber S, Taub E, Bärlocher CB, Burgunder JM. Pallidal deep brain stimulation in patients with cervical dystonia and severe cervical dyskinesias with cervical myelopathy. J Neurol Neurosurg Psychiatry 2002; 72(2): 249–256.
30. Kiss ZH, Doig-Beyaert K, Eliasziw M, Tsui J, Haffenden A, Suchowersky O. The Canadian multicentre study of deep brain stimulation for cervical dystonia. Brain 2007; 130: 2879–2886.
31. Rezai AR, Kopell BH, Gross RE, Vitek JL, Sharan AD, Limousin P, Benabid AL. Deep brain stimulation for Parkinson’s disease: surgical issues. Mov Disord 2006; 21(Suppl 14): S197–S218.
32. Oh MY, Abosch A, Kim SH, Lang AE, Lozano AM. Long-term hardware-related complications of deep brain stimulation. Neurosurgery 2002; 50: 1268–1274; discussion 1274–1276.
33. Beric A, Kelly PJ, Rezai A, Sterio D, Mogilner A, Zonenshayn M, Kopell B. Complications of deep brain stimulation surgery. Stereotact Funct Neurosurg 2001; 77: 73–78.
34. Goodman RR, Kim B, McClelland S 3rd, Senatus PB, Winfield LM, Pullman SL, Yu Q, Ford B, McKhann GM. Operative techniques and morbidity with subthalamic nucleus deep brain stimulation in 100 consecutive patients with advanced Parkinson’s disease. J Neurol Neurosurg Psychiatry 2006; 77: 12–17.
35. Seijo FJ, Alvarez-Vega MA, Gutierrez JC, Fdez-Glez F, Lozano B. Complications in subthalamic nucleus stimulation surgery for treatment of Parkinson’s disease. Review of 272 procedures. Acta Neurochir (Wien) 2007; 149: 867–875; discussion 876. Epub 2007 Aug 14.
36. Vesper J, Haak S, Ostertag C, Nikkhah G. Subthalamic nucleus deep brain stimulation in elderly patients– analysis of outcome and complications. BMC Neurol 2007; 7: 7.
37. Blomstedt P, Hariz MI. Hardware-related complications of deep brain stimulation: a ten year experience. Acta Neurochir (Wien) 2005; 147: 1061–1064; discussion 1064. Epub 2005 Jul 25.
38. Urgošík D., Jech R., Růžička E. Hluboká mozková stimulace u nemocných s extrapyramidovými poruchami pohybu – stereotaktická procedura a intraoperační nálezy. Cesk Slov Neurol N 2011; 74/107.
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