Lymphogranuloma venereum
Authors:
Daniela Vaňousová 1; Hana Zákoucká 2; Jaroslav Marvan 3; David Jilich 4; Naděžda Vojáčková 1; Jana Hercogová 1; Ladislav Machala 5
Authors place of work:
Dermatovenerologická klinika 2. LF UK a Centrum pro pohlavní nemoci Nemocnice Na Bulovce, Praha
1; Národní referenční laboratoř pro chlamydie, Státní zdravotní ústav, Praha
2; Chirurgická klinika a Nemocnice Na Bulovce, Praha
3; Klinika infekčních a tropických nemocí 1. LF UK a Nemocnice Na Bulovce, Praha
4; Klinika infekčních, parazitárních a tropických nemocí 3. LF UK a Nemocnice Na Bulovce, Praha
5
Published in the journal:
Čas. Lék. čes. 2012; 151: 523-526
Category:
Review Articles
Summary
Lymphogranuloma venereum is a sexually transmitted disease caused by serovars L1–3 of Chlamydia trachomatis. This infection was originally endemic in tropics and transmitted predominantly by heterosexual contact but since the beginning of the century it spreads in industrialized countries mainly among men having sex with men causing them severe proctitis. In the Czech Republic the first case was diagnosed in 2011. Lymphogranuloma venereum can resemble other forms of anorectal disorders inclusive inflammatory bowel diseases and thus it must be included into differential diagnostic considerations. Definitive diagnosis is based on detection of specific serovars of Chlamydia trachomatis by polymerase chain reaction. In patients with lymphogranuloma venereum it is also necessary to exclude other sexually transmitted diseases, particularly syphilis, HIV and also hepatitis C. The therapy of choice is doxycycline administered for three weeks.
Key words:
Chlamydia trachomatis, serovar L, biovar LGV, proctitis, lymphogranuloma venereum, HIV.
Zdroje
1. Kropp RY, Wong T. Emergence of lymphogranuloma venereum in Canada. Cmaj 2005; 172(13): 1674–1676.
2. Ronn MM, Ward H. The association between lymphogranuloma venereum and HIV among men who have sex with men: systematic review and meta-analysis. BMC Infect Dis 2011; 11: 70.
3. Savage EJ, van de Laar MJ, Gallay A, et al. Lymphogranuloma venereum in Europe, 2003–2008. Euro Surveill 2009; 14(48): 20055.
4. Snake S, Resl V, Hrabák J, et al. Lymphogranuloma venereum: už i u nás? Česko-slovenská dermatologie 2010; 85(3): 164–168.
5. Kuklová I, Trýzna R, Kojanová M, et al. Chlamydiové infekce. Česko-slovenská dermatologie 2011; 86(5): 219–223.
6. Vaňousová D, Zákoucká H, Jilich D, et al. First detection of Chlamydia trachomatis LGV biovar in the Czech Republic, 2010–2011. Euro Surveill 2012; 17(2).
7. Wang SP, Kuo CC, Barnes RC, et al. Immunotyping of Chlamydia trachomatis with monoclonal antibodies. J Infect Dis 1985; 152(4): 791–800.
8. Everett KD, Bush RM, Andersen AA. Emended description of the order Chlamydiales, proposal of Parachlamydiaceae fam. nov. and Simkaniaceae fam. nov., each containing one monotypic genus, revised taxonomy of the family Chlamydiaceae, including a new genus and five new species, and standards for the identification of organisms. Int J Syst Bacteriol 1999; 49 Pt 2: 415–440.
9. Baneke A. Review: Targeting trachoma: Strategies to reduce the leading infectious cause of blindness. Travel Med Infect Dis 2012; 10(2): 92–96.
10. Peipert JF. Clinical practice. Genital chlamydial infections. N Engl J Med 2003; 349(25): 2424–2430.
11. Rizzo A, Domenico MD, Carratelli CR, et al. The role of Chlamydia and Chlamydophila infections in reactive arthritis. Intern Med 2012; 51(1): 113–117.
12. Zar HJ. Neonatal chlamydial infections: prevention and treatment. Paediatr Drugs 2005; 7(2): 103–110.
13. Stamm W, Jones R, BE B. Chlamydia trachomatis (Trachoma, Perinatal Infections, Lymphogranuloma Venereum and Other Genital Infections). In: Mandell G, Bennet J, Dolin R, eds. Principles and Practice of Infectious Diseases, 6 ed, vol 2. Philadelphia. Pennsylvania: Elsevier Churchill Livingstone 2005; 2239–2255.
14. Blank S, Schillinger JA, Harbatkin D. Lymphogranuloma venereum in the industrialised world. Lancet 2005; 365(9471): 1607–1608.
15. van Veen MG, Koedijk FD, van der Sande MA. STD coinfections in The Netherlands: Specific sexual networks at highest risk. Sex Transm Dis 2010; 37(7): 416–422.
16. van de Laar MJ, Götz HM, de Zwart O, et al. Lymphogranuloma venereum among men who have sex with men-Netherlands, 2003-2004. MMWR Morb Mortal Wkly Rep 2004; 53(42): 985–988.
17. Mabey D, Peeling RW. Lymphogranuloma venereum. Sex Transm Infect 2002; 78(2): 90–92.
18. Gupta S, Ajith C, Kanwar AJ, et al. Genital elephantiasis and sexually transmitted infections - revisited. Int J STD AIDS 2006; 17(3): 157–165; quiz 166.
19. White JA. Manifestations and management of lymphogranuloma venereum. Curr Opin Infect Dis 2009; 22(1): 57–66.
20. Peuchant O, Baldit C, Le Roy C, et al. First case of Chlamydia trachomatis L2b proctitis in a woman. Clin Microbiol Infect 2011; 17(12): E21–23.
21. Verweij SP, Ouburg S, de Vries H, et al. The first case record of a female patient with bubonic lymphogranuloma venereum (LGV), serovariant L2b. Sex Transm Infect 2012.
22. Perenboom RM. Lymphogranuloma venereum proctitis: An emerging sexually transmitted disease in HIV-positive men in the Netherlands. Drugs Today (Barc) 2006; 42 Suppl A: 43–45.
23. Herida M, de Barbeyrac B, Sednaoui P, et al. Rectal lymphogranuloma venereum surveillance in France 2004–2005. Euro Surveill 2006; 9(11): 155–156.
24. Satinsky S, Rosenberger JG, Schick V, et al. USA study of sex toy use by HIV-positive men who have sex with other men: implications for sexual health. Int J STD AIDS 2011; 22(8): 442–448.
25. Rosenberger JG, Schick V, Herbenick D, et al. Sex toy use by gay and bisexual men in the United States. Arch Sex Behav 2011; 41(2): 449–458.
26. Cosentino LA, Campbell T, Jett A, et al. Use of nucleic acid amplification testing for diagnosis of anorectal sexually transmitted infections. J Clin Microbiol 2012; 50(6): 2005–2008.
27. Rodriguez P, Vekris A, de Barbeyrac B, et al. Typing of Chlamydia trachomatis by restriction endonuclease analysis of the amplified major outer membrane protein gene. J Clin Microbiol 1991; 29(6): 1132–1136.
28. Morre SA, Spaargaren J, Fennema JS, et al. Molecular diagnosis of lymphogranuloma venereum: PCR-based restriction fragment length polymorphism and real-time PCR. J Clin Microbiol 2005; 43(10): 5412–5413; author reply 5412–5413.
29. Mahony JB, Luinstra KE, Tyndall M, et al. Multiplex PCR for detection of Chlamydia trachomatis and Neisseria gonorrhoeae in Genitourinary specimens. J Clin Microbiol 1995; 33(11): 3049–3053.
30. Bassiri M, Mardh PA, Domeika M. Multiplex AMPLICOR PCR screening for Chlamydia trachomatis and Neisseria gonorrhoeae in women attenting non-sexually transmitted disease clinics. The European Chlamydia Epidemiology Group. J Clin Microbiol 1997; 35(10): 2556–2560.
31. Marshall R, Chernesky M, Jang D, et al. Characteristics of the m2000 automated sample preparation and multiplex real-time PCR system for detection of Chlamydia trachomatis and Neisseria gonorrhoeae. J Clin Microbiol 2007; 45(3): 747–751.
32. Muvunyi CM, Dhont N, Verhelst R, et al. Evaluation of a new multiplex polymerase chain reaction assay STDFinder for the simultaneous detection of 7 sexually transmitted disease pathogens. Diagn Microbiol Infect Dis 2011; 71(1): 29–37.
33. Smelov V, Morre SA, de Vries HJ. Are serological chlamydia-specific markers useful to detect asymptomatic cases of lymphogranuloma venereum proctitis? Sex Transm Infect 2008; 84(1): 77; author reply 77–78.
34. Morre SA, Ouburg S, van Agtmael MA, et al. Lymphogranuloma venereum diagnostics: from culture to real-time quadriplex polymerase chain reaction. Sex Transm Infect 2008; 84(4): 252–253.
35. de Vries HJ, Morre SA, White JA, et al. European guideline for the management of lymphogranuloma venereum, 2010. Int J STD AIDS 2010; 21(8): 533–536.
36. Workowski KA, Berman SM. Sexually transmitted diseases treatment guidelines, 2006. MMWR Recomm Rep 2006; 55(RR-11): 1–94.
37. Nechvátal A, Mašek T, Hoch J, et al. Gonoroická proktitida imitující proctalgia fugax. Čas. Lék. čes. 2004; 143(4): 264–265.
38. Atkinson K, Bradshaw DM, Nwokolo N. A patient with rectal discharge and fever. BMJ 2011; 343: d5981.
39. van der Bij AK, Spaargaren J, Morre SA, et al. Diagnostic and clinical implications of anorectal lymphogranuloma venereum in men who have sex with men: a retrospective case-control study. Clin Infect Dis 2006; 42(2): 186–194.
40. Hoie S, Knudsen LS, Gerstoft J. Lymphogranuloma venereum proctitis: a differential diagnose to inflammatory bowel disease. Scand J Gastroenterol 2011; 46(4): 503–510.
41. Gallegos M, Bradly D, Jakate S, et al. Lymphogranuloma venereum proctosigmoiditis is a mimicker of inflammatory bowel disease. World J Gastroenterol 2012; 18(25): 3317–3321.
42. Cunningham SE, Johnson MD, Laczek JT. Lymphogranuloma venereum proctitis. Gastrointest Endosc 2012; 75(6): 1269–1270.
43. Taylor G, Dasari BV, McKie L, et al. Lymphogranuloma venerum (LGV) proctitis mimicking rectal cancer. Colorectal Dis 2011; 13(4): e63–64.
44. McLean CA, Stoner BP, Workowski KA. Treatment of lymphogranuloma venereum. Clin Infect Dis 2007; 44(Suppl 3): S147–152.
45. Potterat JJ. 2010 European guideline for Chlamydia trachomatis infections: recommending partner notification look-back periods. Int J STD AIDS 2011; 22(10): 615.
Štítky
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental HygienistČlánok vyšiel v časopise
Journal of Czech Physicians
- Advances in the Treatment of Myasthenia Gravis on the Horizon
- Spasmolytic Effect of Metamizole
- Metamizole at a Glance and in Practice – Effective Non-Opioid Analgesic for All Ages
- What Effect Can Be Expected from Limosilactobacillus reuteri in Mucositis and Peri-Implantitis?
- Metamizole in perioperative treatment in children under 14 years – results of a questionnaire survey from practice
Najčítanejšie v tomto čísle
- Papilledema and ischemic edema of the optic nerve head
- Enterohaemorrhagic Escherichia coli – dangerous new pathogens
- Lymphogranuloma venereum
- Principles of dealing with human DNA and genotyping information