Adipose tissue in the treatment of androgenic alopecia

Česká verzia

Authors: Athanasios J. Stefanis
Authors place of work: Dermatovenerologická klinika 3. LF UK a FNKV, Praha
Published in the journal: Čas. Lék. čes. 2023; 162: 9-12
Category: Review Article

Summary

Tuková tkáň je komplexní orgán s různými funkcemi. Působí jako zásobárna energie, tepelný izolant a tlumič nárazů a zastává také roli v endokrinním systému. V posledních letech byl objeven její regenerační a protizánětlivý potenciál.

Za tyto funkce jsou zodpovědné různé typy progenitorových, kmenových a zralých buněk jiných než adipocyty, které se nacházejí v tukové tkáni a souhrnně se označují jako stromální vaskulární frakce.

V retikulární dermis tukové buňky obklopují vlasové folikuly a úzce regulují vlasový cyklus. Intradermální progenitorové adipocyty jsou metabolicky aktivní a vylučují řadu signálních molekul, které jsou zodpovědné za indukci anagenní fáze a růst nových vlasů.

V tomto přehledu se zabýváme účinností kmenových buněk odvozených z tukové tkáně při léčbě alopecie v klinických studiích.

Keywords:

Adipose tissue – alopecia – clinical trial – review – adipose-derived stromal/stem cells – hair loss – stromal vascular fraction

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Štítky

Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental Hygienist

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