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Chronic pancreatitis, Indications for Resection Procedures and Postoperative Complications


Authors: J. Kaťuchová;  J. Bober;  P. Závacký
Authors place of work: I. chirurgická klinika LF UPJŠ a FNLP Košice, Slovenská republika, prednosta: prof. MUDr. J. Bober, CSc.
Published in the journal: Rozhl. Chir., 2008, roč. 87, č. 4, s. 200-206.
Category: Monothematic special - Original

Summary

Introduction:
During the past three decades, important advances in understanding of the pathophysiology of chronic pancreatitis improved results of major pancreatic resections. Besides Whipple procedure, Beger and Frey procedures are now frequently performed.

Material and Methods:
Between January 1996 and December 2005, the findings for 65 patients suffer from chronic pancreatitis were analyzed in this retrospective trial at the I. Department of Surgery University Hospital FN LP in Košice. Short-term results were investigated, 30 days after surgery: pancreatic leak, billiary leak and leak from gastrointestinal anastomosis, hemorrhagic complications, delayed gastric emptying, intraabdominal absces.

Results:
The overall mortality rate was 4.6% and morbidity rate was 36.7%. Specific (for pancreatic resection) complications were indentified in 15 patients (23%): pancreatic fistula in 4 patients (6.1%), intra-abdominal absces in 5 patients (7.7%), delayed gastric emptying in 4 patients (6.1%), intra-abdominal bleeding in one patient (1.5%) and trombosis of portal vein in one patient (1.5%). Non-specific complications were in 9 patients, 13%.

Conclusion:
An analysis of postoperative complications shows that type of pancreatic anastomosis as well as using Octreotid have no influence to pancreatic fistula. The texture of pancreas is main risk factor to develope pancreatic fistula. Incidence of postoperative complications depends on blood lose and using transfusion units.

Key words:
chronic pancreatitis – pancreatic resection – complications


Zdroje

1. Alexalis, N., Halloran, C, Raraty, M., Ghaneh, P., Sutton, R, Neopltolemos, J. P. Current standards of surgery for pancreatic cancer. Br. J. Surg., 2004, 91, č. 11, s. 1410–1427.

2. Berberat, P. O., Friess, H., Kleeff, J., Uhl, W., Büchler, M. W. Prevention and treatment of complications in pancreatic cancer surgery. Dig. Surg., 1999, 16, č. 4, s. 327–336.

3. Bober, J., Kraus, L., Hildebrand, T., Sabo-Nácko, J., Chymčák, L, Harbuľák, P., Šudák, M. Pancreatitis chronica-indikácia chirurgickej liečby, výsledky. Fólia Medica Cassoviensia Universitas Šafarikiana, 1996, 53, s. 27–33.

4. Büchler, M. W., Friess, H. Evidence forward, drainage on retreat. Still we ignore and drain!? Ann. Surg., 2006, 224, č. l, s. 8–9.

5. Butturini, G., Marcucci, S., Molinari, E., Macetta, G., Landoni, L., Cripppa, S., Bassi, C. Complications after pancreatico- duodenectomy: the problem of current definitions. J. Hepatobiliary Pancreat. Surg., 2006, 13, č. 3, s. 207–211.

6. Conlon, K. C, Labow, D., Leung, D., Smith, A., Jarnagin, W., Coit, D., Merchant, N., Brennan, M. F. Prospective randomized clinical trial of the value of intraperitoneal drainage after pancreatic rescetion. Ann. Surg., 2001, 234, č. 4, s. 487–494.

7. Černý, J., a kol. Špeciálna chirrugia. 2. Chirurgia brušných orgánov a retroperitonea. 1. vyd., Martin, Osveta 1992. 591 s. ISBN 80-217-0424-1.

8. Hashimoto, N., Ohyanagi, H. Pancreatic juice output and amylase level in the drainage fluid after pancreatoduodenectomy in relation to leakage. Hepato-Gastroenterology, 2002, 49, s. 553–555.

9. Kaťuchová, J., Bober, J., Harbuľák, P. Riziká pankreatickej anastomózy. SK Chir, 2005, 2, č. 5, s. 8–10.

10. Kawai, M., Tani, M, Terasawa, H., Ina, S., Hiromo, S., Nishioka, R., Miyazawa, K., Yamaue, H. Early removal of prophylactic drains reduces the risk of intra-abdominal infections in patients with pancreatic head resection. Ann. Surg., 2006, 224, č. 1, s. 1–7.

11. Kazanjan, K. K., Hines, O. J., Eibl, G., Reber, H. A. Management of pancreatic fistulas after pancreaticoduodenectomy. Arch. Surg., 2005, 140, č. 9, s. 849–855.

12. Keith, R. G. Definition and classification of chronic pancreatitis. World J. Surg., 2003, 27, č. 11, s. 1172–1174.

13. Leffler, J., Polouček, P. Poruchy hojení anastomóz na pankreatu. Rozhl. Chir., 2001, 80, č. 8, s. 432–436.

14. Rumstadt, B. R., Schwab, M., Korth, P., Samman, M., Trede, M. Hemorrhage after pancreatoduodenectomy. Ann. Surg., 1998, 227, č. 2, s. 236–241.

15. Sakorafas, G. H., Tsiotou, A. G. Proximal pancreatectomy in the surgical management of chronic pancreatitis. J. Clin. Gastroenterol., 2002, 34, č. 1, s. 72–76.

16. Shrikhande, S. V., Quereshi, S. S., Rajneesh, N., Shukla, P. J. Pancreatic anastomosis after pancreaticoduodenectomy: Do we need fiarther studies? World J. Surg., 2005, 29, č. 9, s. 1642–1649.

17. Šváb, J. Chirurgické léčení chronické pankreatitidy. 1. vyd., Praha, Grada 2003, 139 s. ISBN 80-247-0541-9.

18. Way, L. W. Současná chirurgická diagnostika a léčba. 1. vyd., Praha, Grada 1998, 1627 s. ISBN 80-7169-397-9.

19. Yeo, Ch. J., Cameron, J. L., Maher, M. M., Sauter, P. K., Zahurak, M L., Talamini, M. A., Lillemoe, K. D., Pitt, H. A. A prospective randomized trial of pancreaticogastrostomy versus pancreaticojejunostomy after pancreaticoduodenectomy. Ann. Surg., 1995, 222, č. 4, s. 580–592.

20. Yeo, C. J., Cameron, J. L., Lillemoe, K. D., Sauter, P. K., Coleman, R. N., Sohn, T. A., Campbell, K. A., Choti, M. A. Does prophylactic octreotide decrease the rates of pancreatic fistula and other complications after pancreaticoduodenectomy? Ann. Surg., 2000, 232, č. 3, s. 419–429.

Štítky
Surgery Orthopaedics Trauma surgery

Článok vyšiel v časopise

Perspectives in Surgery

Číslo 4

2008 Číslo 4
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