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Simultaneous Transplantation of the Kidney and the Islets of Langerhans


Authors: T. Marada;  K. Lipár;  M. Adamec;  P. Girman *;  J. Kříž *;  F. Saudek *
Authors place of work: Klinika transplantační chirurgie, IKEM, přednosta: prof. MUDr. Miloš Adamec, CSc. ;  Klinika diabetologie, IKEM, přednosta: prof. MUDr. František Saudek, DrSc. *
Published in the journal: Rozhl. Chir., 2011, roč. 90, č. 2, s. 111-113.
Category: Monothematic special - Original

Summary

Simultaneous kidney and islet transplantation is recent therapeutic alternative for diabetics with end-stage kidney disease, who are not acceptable for simultaneous pancreas-kidney transplantation. Islet transplantation has less complications but still worse long-term function compared to whole pancreas transplantation.

Key words:
diabetes – islets of Langerhans – kidney – pancreas – transplantation


Zdroje

1. Kelly, W. D., Lillehei, R. C., Merkel, F. K., Idezuki, Y., Goetz, F. C. Allotransplantation of the pancreas and duodenum along with the kidney in diabetic nephropathy. Surgery, 1967; 61: 827–837.

2. Bartoš, V., Vaněk, I. Experience of the Institute for Clinical and Experimental Medicine, Prague, Czechoslovakia. International Handbook of Pancreas Transplantation. Kluwer Academic Publisher, 1989; 423–427.

3. Adamec, M., et al. Transplantace slinivky břišní. Praha, Karolinum, 2006.

4. Robertson, P., Davis, C., Larsen, J., et al. Pancreas transplantation in type 1 diabetes. Diabetes Care, 2004; 27: 105.

5. Venstrom, J. M., McBride, M. A., Rother, K. I., et al. Survival after pancreas transplantation in patients with diabetes and preserved kidney function. JAMA, 2003; 290: 2817–2823.

6. Saudek, F. Léčba diabetu transplantací. Maxdorf, Praha, 2003.

7. Shapiro, A. M. J., Lakey, J. R. T., Ryan, E. A., et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N. Engl. J. Med., 2000; 343: 230–238.

8. Shapiro, A. M., Ricordi, C., Hering, B. J., et al. International trial of the Edmonton protocol for islet transplantation. N. Engl. J. Med., 2006; 355: 1318–1330.

9. Kim, S. J., Yang, T. Y., Jeong, I. K., Lee, M. K., et al. Retransplantation of Islets After Simultaneous Islet-Kidney Transplantation: A Case Report. Transplantation Proceedings, 2003; 35: 476–478.

10. Gerber, P. A., Pavlicek, V., Demartines, N., et al. Simultaneous islet-kidney vs pancreas-kidney transplantation in type 1 diabetes mellitus: a 5 year single centre follow-up. Diabetologia, 2008; 51: 110–119.

11. Lehmann, R., Weber, M., Berthold, P., et al. Successful simultaneous islet-kidney transplantation using a steroid-free immunosuppression: two-year follow-up. Am. J. Transplant., 2004; 4: 1117–1123.

12. Wilczek, H., Jaremko, G., Tydén, G., et al. Evolution of diabetic nephropathy in kidney grafts. Evidence that simultaneously transplanted pancreas exerts a protective efect. Transplantation, 1995; 59: 51–57.

Štítky
Surgery Orthopaedics Trauma surgery

Článok vyšiel v časopise

Perspectives in Surgery

Číslo 2

2011 Číslo 2
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