#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Difficult differential diagnosis of malignant melanoma – case reports


Authors: Inka Třešková 1 ;  K. Pizinger 2;  D. Kacerovská 3;  V. Bursa 1;  T. Kydlíček
Authors place of work: Oddělení plastické chirurgie, FN Plzeň, primář: MUDr. V. Bursa 1;  Dermatovenerologická klinika, FN Plzeň, přednosta: Prof. MUDr. K. Pizinger, CSc. 2;  Šiklův patologicko-anatomický ústav, přednosta: Prof. MUDr. M. Michal 3
Published in the journal: Rozhl. Chir., 2013, roč. 92, č. 11, s. 654-658.
Category: Case Report

Summary

Malignant melanoma is one of the most malignant tumours. If it is diagnosed in the early stage, the prognosis is quite good. Timely diagnosis is essential as well as early surgical removal of the tumour in a specialized centre.

The aim of the article is to highlight the difficult diagnosis and differential diagnosis of malignant melanoma. The authors describe a rare case of malignant melanoma in an eleven-year-old girl, a neglected finding of malignant melanoma in a young man, the difficult differential diagnosis of malignant melanoma and a case of malignant melanoma arising from a congenital naevus.The incidence of malignant melanoma is increasing worldwide, and it is therefore necessary to bear this diagnosis in mind when performing clinical examination of patients and discovering suspected lesions.

Key words:
malignant melanoma – differential diagnosis – therapy


Zdroje

1. Fikrle T, Pizinger K. Maligní melanom. Onkologie 2010;4: 225–228.

2. Fikrle T, Pizinger K. Dermatoscopic differences between atypical melanocytic naevi and thin malignant melanomas. Melanoma Research 2006;16:45–50.

3. Surrenti T, Diociaiuti A, Inserra A, Accinni A, Giraldi L, et al. Melanoma in a 5-year-old Child with a Giant Congenital Melanocytic Naevus. Acta Dermato-Venereologica 2012;92:585–663.

4. Downard CD, Rapkin LB, Gow KW. Melanoma in children and adolescents. Surgical Oncology 2007;16:215–220.

5. Jafarian F, Powell J, Kokta V, Champagne M, Hatami A, et al. Malignant melanoma in childhood and adolescence: report of 13 cases. J Am Acad Dermatol 2005;53:816–22.

6. Mills O, Messina JL. Pediatric melanoma: a review. Cancer Control 2009;16:225–33.

7. Hamm H, Höger PH. Skin tumors in childhood. Dtsch Arztebl Int 2011;108:347–53.

8. Matsushita S, Mera K, Kubo H, Takeda K, Ishihara T, et al. Malignant melanoma with nodal involvement in a 17-year-old female. J Cancer Res Ther 2010;6:404–6.

9. Kim JY, Choi JE, Ahn HH, Kye YC, Seo SH. A case of spitzoid melanoma with lymph node metastasis in a child. J Korean Med Sci 2012;27:454–7.

10. Miranda SG, Kashani-Sabet M, Zedek D, McCalmont TH, Leong SP. Cutaneous Spitzoid melanoma in a very young girl of Asian descent. BMJ Case Rep. 2011 Mar 29.

11. Eggermont AM, Testori A, Marsden J, Hersey P, Quirt I, et al. Utility of adjuvant systemic therapy in melanoma. Ann Oncol 2009; 20 Suppl 6:vi30–4.

12. Bastian BC, Wesselman U, Pinkel D, Leboit PE. Molecular cytogenetic analysis of Spitz nevi shows clear differences to melanoma. J Invest Dermatol 1999;113:1065–9.

13. Bastian BC, Leboit PE, Pinkel D. Mutations and copy number increases of HRAS in Spitz nevi with distinctive histopathological features. Am J Pathol 2000;157:967–72.

14. Reed KB, Brewer JD, Lohse CM, Bringe KE, Pruitt CN, et al. Increasing incidence of melanoma among young adults: an epidemiological study in Olmsted County, Minnesota. Mayo Clin Proc 2012;87:328–34.

15. Purdue MP, Freeman LE, Anderson WF, Tucker MA. Recent trends in incidence of cutaneous melanoma among US Caucasian young adults. J Invest Dermatol 2008;128:2905–8.

16. Roesch A, Volkenandt M. Melanoma. Braun-Falco Dermatology. 3rdEdition, Heidelberg, Springer 2009:1418,1428–1430.

Štítky
Surgery Orthopaedics Trauma surgery
Prihlásenie
Zabudnuté heslo

Zadajte e-mailovú adresu, s ktorou ste vytvárali účet. Budú Vám na ňu zasielané informácie k nastaveniu nového hesla.

Prihlásenie

Nemáte účet?  Registrujte sa

#ADS_BOTTOM_SCRIPTS#