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Heparin-induced thrombocytopenia in a patient with acute thrombosis, acute aortic dissection and acute lower limb ischaemia


Authors: M. Peteja 1,2 ;  J. Chmelo 1;  J. Zuchnická 3;  P. Zonča 2;  M. Mazur 2
Authors place of work: Cévní chirurgie, Vítkovická nemocnice, a. s., primář: MUDr. J. Chmelo 1;  LF OSU a chirurgická klinika FN Ostrava, přednosta: Doc. MUDr. P. Zonča PhD., FRCS. 2;  Ústav klinické hematologie FN Ostrava, přednosta: Prof. MUDr. R. Hájek, CSc. 3
Published in the journal: Rozhl. Chir., 2013, roč. 92, č. 11, s. 650-653.
Category: Case Report

Summary

This case report presents the course of illness, as well as the diagnosis and therapy, of acute thrombosis and abdominal aortic dissection after Fogarty thrombectomy with the symptoms of acute limb ischaemia in a 42-year-old female patient suffering from heparin-induced thrombocytopenia. HIT is a severe iatrogenic complication emerging after unfractionated or low molecular weight heparin administration, with rather easy diagnosis; however, it is often neglected due to the rarity of its occurrence.

Key words:
heparin-thrombocytopenia-platelets-abdominal aortic dissection-abdominal aortic thrombosis


Zdroje

1. Králová S, Klodová D, Gumulec J, Novotná J, Klaricová K, et al. Heparinem indukovaná trombocytopenie, Vnitřní lékařství 2006; 52(S1):98–106.

2. Andělová K, Minář J, Králová S, Hrabcová R, Radina M, et al. Vývoj metodiky v diagnostice heparinem indukované trombocytopenie, Klinická biochemie a metabolismus 2007;15:215–217.

3. Riegerová B, Malý R, Lojík M, Raupach J, Chovanec V, et al. Heparinem indukovaná trombocytopenie II. typu u komplikované ileofemorální flebotrombózy léčené katétrem řízenou trombolýzou, Interv akut kardiologie 2008;7:74–77.

4. Warkentin TE, Kelton JG. Temporal aspects of heparin-induced thrombocytopenia, N Engl J Med 2001;344:1286–1292.

5. Kelton JG, Warkentin TE. Heparin-induced trombocytopenia: a historical perspective, Blood 2008;112:2607–2616.

6. Jaax ME, Greinacher A. Management of heparin-induced thrombocytopenia. Expert Opin Pharmacother 2012;13:987–1006. Epub 2012 Apr 5.

7. Prechel M, Walenga JM. Heparin-induced thrombocytopenia: an update. Semin Thromb Hemost 2012;38:483–96. Epub 2012 Mar 7.

8. Cohen RA, Castellano M, Garcia CHA. Heparin Induced Thrombocytopenia: Case Presentation and Review, J Clin Med Res 2012;4:68–72.

9. Mantelas M, Antonitsis P, Kaitzis D, Hatzibaloglou A, Moros I. Spontaneous isolated dissection of the abdominal aorta:single-center experience, Interactive CardioVascular and Thoracic Surgery 2009;8:398–401.

10. Lo GK, Juhl D, Warkentin TE, Sigouin CS, Eichler P, el al. Evaluation of pretest clinical score (4 Ts) for the diagnosis of heparin-induced thrombocytopenia in two clinical settings. J Thromb Haemost 2006;4:759–65.

Štítky
Surgery Orthopaedics Trauma surgery
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