Characterisation of Candida sp. isolated from patients after abdominal surgery
Authors:
V. Adámková 1,2
; A. Vaňková 1; J. Ulrych 3; K. Matek 3
Authors place of work:
Ústav lékařské biochemie a laboratorní diagnostiky VFN, Praha
přednosta: prof. MUDr. T. Zima, DrSc., MBA
1; Ústav lékařské mikrobiologie LF Univerzity Palackého, Olomouc
přednosta: prof. MUDr. M. Kolář, PhD.
2; Chirurgická klinika VFN, Praha
přednosta: prof. MUDr. Z. Krška, DrSc.
3
Published in the journal:
Rozhl. Chir., 2017, roč. 96, č. 10, s. 426-431.
Category:
Original articles
Summary
Introduction:
Intraabdominal candidiasis (IAC) is the predominant type of invasive candidiasis after candidemia. The majority of epidemiological studies on Candida are focused only on bloodstream infections. Nevertheless, the role of blood cultures has limited application in patients with abdominal candidiasis. IAC, which includes peritonitis and intraabdominal abscesses, may occur in around 40% of patients following repeat gastrointestinal (GI) surgery or GI perforation.
Method:
Retrospective analysis of culture isolates of Candida sp. from clinical specimens of patients after abdominal surgery. The study period was from January 1 to October 31, 2016.
Results:
Our study of 33 patients with findings of Candida sp. from the abdominal cavity found a mortality of 15.2%, the most frequent strain being C. albicans and C. glabrata. All strains of Candida sp. were susceptible to echinocandins.
Conclusions:
Candida sp. is part of normal microbiota of the gastrointestinal tract and its isolation is often difficult to interpret. Unfortunately, the pathophysiologic importance of Candida isolation from the abdominal space is not completely clear in many clinical situations.
Key words:
invasive candidiasis − intra-abdominal candidiasis − laboratory diagnostics
Zdroje
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Štítky
Surgery Orthopaedics Trauma surgeryČlánok vyšiel v časopise
Perspectives in Surgery
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