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Deep-inspiration breath hold radiotherapy in patients with left-sided breast cancer after partial mastectomy

Česká verzia

Authors: M. Doležel 1,2,3;  K. Odrážka 3,4,5;  J. Vaňásek 4
Authors place of work: Onkologická klinika Fakultní nemocnice Olomouc 1;  Lékařská fakulta Univertity Palackého, Olomouc 2;  1. lékařská fakulta Univerzity Karlovy, Praha 3;  KOC Pardubická krajská nemocnice, a. s., a Multiscan, s. r. o., Pardubice 4;  3. lékařská fakulta Univerzity Karlovy, Praha 5
Published in the journal: Rozhl. Chir., 2021, roč. 100, č. 4, s. 180-185.
Category: Original articles
doi: https://doi.org/10.33699/PIS.2021.100.4.

Summary

Introduction: The purpose of this study was to compare the radiation dose to organs at risk for deep-inspiration breath hold (DIBH) and free-breathing (FB) radiotherapy in patients with lef-sided breast cancer undergoing adjuvant radiotherapy after partial mastectomy. 

Methods: One hundred patients with left-sided breast cancer underwent DIBH and FB planning computed tomography scans, and the 2 techniques were compared. Dose-volume histograms were analyzed for heart, left anterior descending coronary artery (LAD), and left lung. 

Results: Radiation dose to heart, LAD, and left lung was significantly lower for DIBH than for free breathing plans. The median mean heart dose for DIBH technique in comparison with FB was 1.21 Gy, and 3.22 Gy respectively; for LAD, 4.67 versus 24.71 Gy; and for left lung 8.32 Gy versus 9.99 Gy. 

Conclusion: DIBH is an effective technique to reduce cardiac and lung radiation exposure.

Keywords:

deep−inspiration breath hold radiotherapy−breast cancer−cardiovascular toxicity−adjuvant radiotherapy

Zdroje
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Perspectives in Surgery

Číslo 4
2021 Číslo 4
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