Advantageous properties of gestodene and its use in combined hormonal contraception

Česká verzia

Authors: Tomáš Fait
Authors place of work: Gynekologicko-porodnická klinika 1. LF UK a VFN Praha, přednosta prof. MUDr. Alois Martan, DrSc.
Published in the journal: Prakt Gyn 2014; 18(2): 110-113
Category: Gynecology and Obstetrics: Review Article

Summary

Gestodene is a derivative of 19-nortestosterone and gonan with no residual androgenic activity. It belongs to the 3rd generation of progestins. Monophasic combination of 20 µg EE and 75 µg GSD has been clinically proven contraceptive with high efficiency and high compliance of patients. In trials it has been shown its metabolic neutrality, minimal risk in body weight changes, no blood pressure changes, sufficient anti-androgenic effect and good control of pseudomenstruation cycle.

Key words:
combined oral contraceptives – gestodene

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