The current knowledge about the risk of human reproductive disorders posed by prenatal exposure to nicotine and smoking

Česká verzia

Authors: Drahoslava Hrubá
Authors place of work: Ústav ochrany a podpory zdraví LF MU, Brno
Published in the journal: Prakt Gyn 2016; 20(2): 97-100
Category: Gynecology and Obstetrics

Summary

Maternal smoking during pregnancy may inversaly affect the intrauterine environment and early fetal exposure may have a detrimental effects on health in later life. The wide spectrum of damages includes also the reproductive functions. Although the results of experimental studies are more often similar than the clinical human studies, they allow to understand the mechanisms of action and predict the role of exposure to tobacco and to the other harmful chemicals in the tobacco and/or cigarette smoke early in life to the increasing trends in human infertility.

Key words:
smoking – nicotine – prenatal exposure – damages of fertility – puberty – congenital malformations

Zdroje

1. Doručeno do redakce 4. 12. 2015Hrubá D. Riziko kouření v těhotenství se stále podceňuje: tolerovat kouření v těhotenství je neodborné a neetické. Prakt Gyn 2011; 15(1): 1–7.

2. Wong MK, Barra NG, Alfaidy N et al. Adverse effects of perinatal nicotine exposure on reproductive outcomes. Reproduction 2015; 150(6): R185-R193.

3. Henderson BJ, Lester HA. Inside-out neuropharmacology of nicotine drugs. Neuropharmacology 2015; 96(Pt B):178–193.

4. Benowitz NL, Hukkanen J, Jacob P. Nicotine chemistry, metabolism, kinetics and biomarkers. Handb Exp Pharmacol 2009; (192): 29–60.

5. Lassen TH, Madsen M, Skovgaaed LT et al. Matenal use of nicotine replacement therapy during pregnancy and offspring birthweight: a study within the Danish National Birth Cohort. Paediatr Perinat Epidemiol 2010; 24(3): 272–281.

6. Wang T, Chen M, Van YE et al. Growth retardation of feral rats exposed to nicotine in utero: possible involvement of CYP1A1, CYP2E1, and P glycoprotein. Environ Toxicol 2009; 24(1):33–42.

7. Etter JF. Levels of saliva cotinine in electronic cigarette users. Addiction 2014; 109(5): 825–829.

8. Cao SS, Kaufman RJ. Endoplasmatic reticulum stress and oxidative stress in cell fate decision and human disease. Antioxid Redox Signal 2014; 21(3): 396–413.

9. Holloway AC, Salomon A, Soares MJ et al. Characterization of the adverse effects of nicotine in placental development: in vivo and in vitro studies. Am J Physiol Endocrinol Metab 2014; 306(4): E443-E456.

10. 10.Lin C, Schabel MC, Roberts VH et al. 4-O-methylhonokiol inhibits serious embryo anomalies caused by nicotine via modulations of oxidative stress, apoptosis, and inflammation. Birth Defects Res B Dev Reprod Toxicol 2014; 101(2): 125–134.

11. Kawakami T, Yoshimi M, Kadota Y et al. Prolonged endoplasmatic reticulum stress alters placental morphology and causes low birth weight. Toxicol Appl Pharmacol 2014; 275(2): 134–144.

12. Yang Y, Pei X, Jin Y et al. The roles of endoplasmic reticulum stress response in female mammalian reproduction. Cell Tissue Res 2016; 363(3): 589–597.

13. Zhu Z, Xu W, Dai J et al. The alteration of protein profile induced by cigarette smoking via oxidative stress in mice epididymis. Int J Biochem Cell Biol 2013; 45(3): 571–582.

14. Mamsen LS, Lutterodt MC, Andersen EW et al. Cigarette smoking during pregnancy reduces the number of embryogenic germ and somatic cells. Hum Reprod 2010; 25(11): 2755–2761.

15. Sobinoff AP, Sutherland JM, Beckett EL et al. Damaging legacy: maternal cigarette smoking has long-term consequences for male offspring fertility. Hum Reprod 2014;29(12): 2719–2735. Dostupné z DOI: <http://dx.doi.org/10.1093/humrep/deu235>.

16. Sobinoff AP, Beckett EL, Jarnicki AG et al. Cigarette smoke exposure causes antral follicle destruction and oocyte dysfunction through oxidative stress. Toxicol Appl Pharmacol 2013; 271(2): 156–167.

17. Skakkenbaek NE, Rajpert-De Meyts E, Main KM. Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental spects. Hum Reprod 2001; 16(5): 972–978.

18. Buck Louis GM, Cooney MA, Peterson CM. The ovarian dysgenesis syndrome. J Dev Origins Health Dis 2011; 2(1): 25–35. Dostupné z DOI: <http://dx.doi.org/10.1017/S2040174410000693>.

19. MacLeod DJ, Sharpe EM, Welsh M et al. Androgen action in the masculinization programming window and development of male reproductive organs. Int J Androl 2010; 33(2): 279–287.

20. Strohsnitter WC, Hatch EE, Hyer M, Troisi R et al. The association between in utero cigarette smoke exposure and age of menopause. Am J Epidemiol 2008; 167(6): 727–733.

21. Ye X, Skjaerven R, Basso O et al. In utero exposure to tobacco smoke and subsequent reduced ferility in females. Hum Reprod 2010; 25(11): 2901–2906.

22. Hakonsen LB, Ernst A, Ramlau-Hansesn CH. Maternal cigarette smoking during pregnancy and reproductive health in children: a review of epidemiological studies. Asian J Androl 2014; 16(1): 39–49.

23. Hrubá D, Kukla L, Okrajek P et al. Vliv perikonepční expozice kouření na mužskou reprodukci, poměr pohlaví a nástup puberty. Čes Slov Pediatr 2013; 68(5): 283–292.

24. Jensen MS, Toft G, Thulstrup AM et al. Cryptorchidism according to maternal gestational smoking. Epidemiology 2007; 18(2): 220–225.

25. Damgaard IN, Jensen TK. (Nordic Cryptorchidism Study Group). Risk factors for congenital cryptorchidism in a prospective birth cohort study. PloS One 2008; 3(8): e3051. Dostupné z DOI: <http://dx.doi.org/10.1371/journal.pone.0003051>.

26. Hackshaw A, Rodeck C, Boniface S. Maternal smoking in pregnancy and birth defects: a systematic review based on 173 687 maternal cases and 11.7 million controls. Hum Reprod Update 2011; 17(5): 589–604.