Can semi-quantitative analysis of amniotic fluid glucose be useful in gynecology and obstetrics? A pilot study.

Česká verzia

Authors: Beáta Veliká ¹; Anna Birková ¹; Rastislav Dudič ²; Ivana Špaková ¹; Peter Urdzík ²
Authors place of work: Ústav lekárskej a klinickej biochémie LF UPJŠ v Košiciach ¹; Gynekologicko-pôrodnícka klinika LF UPJŠ v Košiciach a UNLP Košice ²
Published in the journal: Prakt Gyn 2016; 20(3-4): 138-142
Category: Gynecology and Obstetrics

Summary

Amniotic fluid represent a biological fluid, which reflect metabolic state of the fetus, the study of its components and their changes in different gestational weeks provide useful information about the growth and maturation of the fetus under physiological, as well as pathological conditions. Concentration of glucose in amniotic fluid is considered as predictive marker of fetus weight, of intrauterine infection, it reflects the fetal maturity, maternal metabolic state, but is also connected with some births defects. In our study, we focused on the detection of specific gravity, proteins, nitrites, pH, leukocytes and glucose level in amniotic fluid, in different weeks of pregnancy by diagnostic strips. Very interesting results were obtained in the semi-quantitative evaluation of glucose concentration. Under physiological conditions the glucose concentration in amniotic fluid progressively decreases with weeks of pregnancy, on the basis of which it is foreseeable potential use of rapid-strip tests and in clinical practice, where available amniotic fluid.

Key words:
amniotic fluid – glucose –strip test

Zdroje

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