EVIDENCE-BASED CLINICAL APPROACH TO ANDROGEN SUPPRESSION AND RADIOTHERAPY IN MALE PATIENTS WITH LOCALLY ADVANCED OR LOCALIZED CARCINOMA OF THE PROSTATE
Authors:
MUDr. Vítězslav Vít; Prof. MUDr. Dalibor Pacík, CSc.
Authors place of work:
Urologická klinika LF MU a FN Brno
pracoviště Bohunice
Published in the journal:
Urol List 2006; 4(4): 45-49
Summary
The article deals with issues of radiotherapy in the treatment of localized or locally advanced carcinoma of the prostate. The different modalities of external radiotherapy are addressed including their complications, and brachyradiotherapy as a method offering good prospects in this country is mentioned.
Also included are the options for the reduction of risk of prostate carcinoma recurrence after primary therapy with currative intention. Based on analysis of clinical studies, neoadjuvant and adjuvant hormonal deprivation is assessed for its effect on the course of prostate carcinoma after radiotherapy with currative intention.
The author's conclusion is that neoadjuvant and adjuvant androgen deprivation enhances local control of the tumour, extends the time to dissemination and increases total survival in patients after radiotherapy with currative intention.
KEY WORDS:
prostate carcinoma, radiotherapy, neoadjuvant androgen deprivation, adjuvant androgen deprivation
Zdroje
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Štítky
Paediatric urologist UrologyČlánok vyšiel v časopise
Urological Journal
2006 Číslo 4
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