NEW TRENDS IN SYSTEMIC TREATMENT OF RENAL CANCER
Authors:
Z. Kirkali
Authors place of work:
Professor of Urology, Dokuz Eylul University School of Medicine, Inciralti, Izmir, Turkey
Published in the journal:
Urol List 2010; 8(2): 33-47
Summary
Better understanding of renal cell carcinoma (RCC) biology raised interest in the research of novel therapeutic approaches based on targeted therapies. Targeted therapies can be defined as use of agents aimed at predefined exocellular, transmembranous and intracellular molecules present at pathways responsible for growth, differentation, transcription or angiogenesis control. The author of this article reviews currently available targeted medicamentous therapies for RCC treatment based on up-to-date data from recent studies.
Key words:
RCC, targeted therapies, sorafenib, sunitinib, bevacizumab, interleukin-2, mTOR, VEGF, angiogenesis inhibitors
Zdroje
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Štítky
Paediatric urologist UrologyČlánok vyšiel v časopise
Urological Journal
2010 Číslo 2
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