Simultaneous ipsilateral native nephrectomy with kidney transplantation for the patiens with polycystic kidney disease

Česká verzia

Authors: K. Morita; T. Hirose; H. Sasaki; M. Masayoshi; T. Tanabe; D. Iwami; K. Hotta; N. Fukuzawa; K. Nonomura
Published in the journal: Urol List 2013; 11(1): 27-30

Summary

Prevention of perioperative complications related to an enlarged polycystic native kidney is mandatory when performing kidney transplantation for end-stage renal disease (ESRD) patients with polycystic kidney disease (PKD). The clinical course and outcome of kidney transplantation were retrospectively reviewed in ESRD patients with PKD. Eleven patients (6 males and 5 females; median age 54 years, age range 37–67 years at transplantation) were enrolled in this study. The median postoperative observation period was 35 (9–134) months. The native ipsilateral kidney was simultaneously removed with transplantation except for one case whose native kidney had been removed previously due to infection. All recipients are alive with functioning grafts. The median most recent serum creatinine level was 1.08 (0.67–3.17) mg/dl. Overall, 4 patients experienced acute rejection, 2 had viral infections, 2 had a bacterial native kidney infection (nephrectomized in 1), and 1 had ileus. Remaining kidney size was reduced in 6 patients, with no change in 4 and increased in only 1 patient who underwent native nephrectomy 11 years after transplantation. Native kidneys of PKD patients mostly reduce in size following successful kidney transplantation. Ipsilateral nephrectomy for the purpose of securing allograft space at transplantation is a safe and preferred procedure.

Key words:
complications, end-stage renal disease, kidney transplantation, native nephrectomy, polycystic kidney disease

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