Functional Significance of a Temporal Lobe

Česká verzia

Authors: J. Kotašková; P. Marusič
Authors place of work: Neurologická klinika 2. LF UK a FN v Motole, Praha
Published in the journal: Cesk Slov Neurol N 2010; 73/106(4): 387-391
Category: Přehledný referát

Summary

The temporal pole is the least explored part of the temporal lobe, and not only anatomically. Its functional significance is also poorly understood. Due to the large number of connections with the amygdala and orbitofrontal cortex involved, the temporal pole is assumed to be part of the limbic system. It is involved in recognition of facial and emotional features, social-emotional empathy (theory of mind), naming of objects and persons and other memory functions, matters that are not routinely tested in neuropsychological assessment. An important expansion of knowledge of temporal pole functions has been enabled by the use of functional neuro-imaging methods, especially positron emission tomography and functional magnetic resonance. An impairment of functions associated with the temporal pole has been observed in Alzheimer’s disease, schizophrenia and psychosis. The aim of this review is to summarize basic knowledge of temporal pole function in temporal lobe epilepsy patients.

Key words:
temporal pole – epilepsy – emotion recognition – social cognition – theory of mind

Zdroje

1. Lavenex P, Suzuki WA, Amaral DG. Perirhinal and parahippocampal cortices of the macaque monkey: Intrinsic projections and interconnections. J Comp Neurol 2004; 472(3): 371–394.

2. Blaizot X, Mansilla F, Insausti AM, Constans JM, Salinas-Alamán A, Pró-Sistiaga P et al. The Human Parahippocampal Region I. Temporal Pole Cytoarchitectonic and MRI Correlation. Cereb Cortex. In press 2010.

3. Chabardès S, Kahane P, Minotti L, Hoffmann D, Benabid AL. Anatomy of the temporal pole region. Epileptic Disord 2002; 4 (Suppl 1): S9–S15.

4. Kier EL, Staib LH, Davis LM, Bronen RA. MR imaging of the temporal stem: anatomic dissection tractography of the uncinate fasciculus, inferior occipitofrontal fasciculus, and Meyer‘s loop of the optic radiation. AJNR Am J Neuroradiol 2004; 25(5): 677–691.

5. Morecraft RJ, Geula C, Mesulam MM. Cytoarchitecture and neural afferents of orbitofrontal cortex in the brain of the monkey. J Comp Neurol 1992; 323(3): 341–358.

6. Benedetti F, Bernasconi A, Bosia M, Cavallaro R, Dallaspezia S, Falini A et al. Functional and structural brain correlates of theory of mind and empathy deficits in schizophrenia. Schizophr Res 2009; 114(1–3): 154–160.

7. Mier D, Sauer C, Lis S, Esslinger C, Wilhelm J, Gallhofer B et al. Neuronal correlates of affective theory of mind in schizophrenia out-patients: evidence for a baseline deficit. Psychol Med. In press 2010.

8. Schacher M, Winkler R, Grunwald T, Kraemer G, Kurthen M, Reed V et al. Mesial temporal lobe epilepsy impairs advanced social cognition. Epilepsia 2006; 47(12): 2141–2146.

9. Olson IR, Plotzker A, Ezzyat Y. The Enigmatic temporal pole: a review of findings on social and emotional processing. Brain 2007; 130 (Pt 7): 1718–1731.

10. Horel JA, Pytko-Joiner DE, Voytko ML, Salsbury K. The performance of visual tasks while segments of the inferotemporal cortex are suppressed by cold. Behav Brain Res 1987; 23(1): 29–42.

11. Maguire EA, Frith CD, Morris RG. The functional neuroanatomy of comprehension and memory: the importance of prior knowledge. Brain 1999; 122 (Pt 10): 1839–1850.

12. Cabeza R, Nyberg L. Imaging cognition II: An empirical review of 275 PET and fMRI studies. J Cogn Neurosci 2000; 12(1): 1–47.

13. Cabeza R, Nyberg L. Neural bases of learning and memory: functional neuroimaging evidence. Curr Opin Neurol 2000; 13(4): 415–421.

14. Brazdil M, Roman R, Urbanek T, Chladek J, Spok D, Marecek R et al. Neural correlates of affective picture processing – a depth ERP study. Neuroimage 2009; 47(1): 376–383.

15. Völlm BA, Taylor AN, Richardson P, Corcoran R, Stirling J, McKie S et al. Neuronal correlates of theory of mind and empathy: a functional magnetic resonance imaging study in a nonverbal task. Neuroimage 2006; 29(1): 90–98.

16. Bohbot VD, Kalina M, Stepankova K, Spackova N, Petrides M, Nadel L. Spatial memory deficits in patients with lesions to the right hippocampus and to the right parahippocampal cortex. Neuropsychologia 1998; 36(11): 1217–1238.

17. Glikmann-Johnston Y, Saling MM, Chen J, Cooper KA, Beare RJ, Reutens DC. Structural and functional correlates of unilateral mesial temporal lobe spatial memory impairment. Brain 2008; 131 (Pt 11): 3006–3018.

18. Killgore WD, Yurgelun-Todd DA. The right-hemisphere and valence hypotheses: could they both be right (and sometimes left)? Soc Cogn Affect Neurosci 2007; 2(3): 240–250.

19. Seidenberg M, Griffith R, Sabsevitz D, Moran M, Haltiner A, Bell B et al. Recognition and identification of famous faces in patients with unilateral temporal lobe epilepsy. Neuropsychologia 2002; 40(4): 446–456.

20. Ahern GL, Schwartz GE. Differential lateralization for positive versus negative emotion. Neuropsychologia 1979; 17(6): 693–698.

21. McClelland S 3rd, Garcia RE, Peraza DM, Shih TT, Hirsch LJ, Hirsch J et al. Facial emotion recognition after curative nondominant temporal lobectomy in patients with mesial temporal sclerosis. Epilepsia 2006; 47(8): 1337–1342.

22. Schacher M, Haemmerle B, Woermann FG, Okujava M, Huber D, Grunwald T et al. Amygdala fMRI lateralizes temporal lobe epilepsy. Neurology 2006; 66(1): 81–87.

23. Meletti S, Benuzzi F, Rubboli G, Cantalupo G, Stanzani Maserati M, Nichelli P et al. Impaired facial emotion recognition in early-onset right mesial temporal lobe epilepsy. Neurology 2003; 60(3): 426–431.

24. Meletti S, Benuzzi F, Cantalupo G, Rubboli G, Tassinari CA, Nichelli P. Facial emotion recognition impairment in chronic temporal lobe epilepsy. Epilepsia 2009; 50(6): 1547–1559.

25. Rapcsak SZ, Galper SR, Comer JF, Reminger SL, Nielsen L, Kaszniak AW et al. Fear recognition deficits after focal brain damage: a cautionary note. Neurology 2000; 54(3): 575–581.

26. Ammerlaan EJ, Hendriks MP, Colon AJ, Kessels RP. Emotion perception and interpersonal behavior in epilepsy patients after unilateral amygdalohippocampectomy. Acta Neurobiol Exp (Wars) 2008; 68(2): 214–218.

27. Benton AL, van Allen MW. Prosopagnosia and facial discrimination. J Neurol Sci 1972; 15(2): 167–172.

28. Bruce V, Young A. Understanding face recognition. Br J Psychol 1986; 77 (Pt 3): 305–327.

29. Glosser G, Salvucci AE, Chiaravalloti ND. Naming and recognizing famous faces in temporal lobe epilepsy. Neurology 2003; 61(1): 81–86.

30. Vuilleumier P, Mohr C, Valenza N, Wetzel C, Landis T. Hyperfamiliarity for unknown faces after left lateral temporo-occipital venous infarction: a double dissociation with prosopagnosia. Brain 2003; 126 (Pt 4): 889–907.

31. Gonsalves BD, Kahn I, Curran T, Norman KA, Wagner AD. Memory strength and repetition suppression: multimodal imaging of medial temporal cortical contributions to recognition. Neuron 2005; 47(5): 751–761.

32. Bowles B, Crupi C, Mirsattari SM, Pigott SE, Parrent AG, Pruessner JC et al. Impaired familiarity with preserved recollection after anterior temporal-lobe resection that spares the hippocampus. Proc Natl Acad Sci U S A 2007; 104(41): 16382–16387.

33. Todorov A, Olson IR. Robust learning of affective trait associations with faces when the hippocampus is damaged, but not when the amygdala and temporal pole are damaged. Soc Cogn Affect Neurosci 2008; 3(3): 195–203.

34. Mitchell JP. Inferences about mental states. Philos Trans R Soc Lond B Biol Sci 2009; 364(1521): 1309–1316.

35. Kirsch HE, Grossman M. Tracing the roots and routes of cognitive dysfunction in epilepsy. Neurology 2008; 71(23): 1854–1855.

36. Adolphs R. The social brain: neural basis of social knowledge. Annu Rev Psychol 2009; 60: 693–716.

37. Borod JC, Haywood CS, Koff E. Neuropsychological aspects of facial asymmetry during emotional expression: a review of the normal adult literature. Neuropsychol Rev 1997; 7(1): 41–60.

38. Leijten FS, Alpherts WC, Van Huffelen AC, Vermeulen J, Van Rijen PC. The effects on cognitive performance of tailored resection in surgery for nonlesional mesiotemporal lobe epilepsy. Epilepsia 2005; 46(3): 431–439.